Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells.
Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man.
Binds to serum IgG.
Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells.
May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells.
May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
宿主种属
小鼠(Mouse)
特异性
Human CLEC4C
种属反应性
人(Human)
阳性对照
Flow Cytometry: Human peripheral mononuclear cells
偶联
Unconjugated
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.4
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融.
图片
Recombinant CLEC4C/CD303 Antibody (Ab222898) - Flow Cytometry Multicolor flow cytometric analysis of CLEC4C/CD303 expression on human peripheral blood mononuclear cells. Human PBMC were stained with Recombinant CD19 Antibody (FITC) (Ab224671), IL3RA/CD123 Mouse mAb (APC) (Ab181967) and either Mouse IgG (Biotin) (Ab180306; Left panel) or Recombinant CLEC4C/CD303 Antibody (Ab222898; Right panel) conjugated with biotin at 1.0 μg/mL for 1 hour at 4°C and detected with SA-PE (rp156150). A bivariate pseudocolor density plot showing the correlated expression of CLEC4C/CD303 (or Isotype control staining) was derived from CD19- gated events with the forward and side light-scatter characteristics of PBMC.
Recombinant CLEC4C/CD303 Antibody (Ab222898) - SEC The purity of Recombinant CLEC4C/CD303 Antibody (Ab222898) is more than 95% verified by HPLC.
ZJ25F0926640
危险品化学品经营许可证（带存储）