May have a pivotal role in cell differentiation of different cell types. May have a specific role in early thymocyte development. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses (By similarity).
In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.
Plays a role in the control of autoimmunity.
宿主种属
大鼠(Rat)
特异性
Mouse CD24
种属反应性
小鼠(Mouse)
免疫原
C57BL/10 Mouse Splenic T Lymphocytes
阳性对照
Flow Cytometry: C57BL/6 Mouse splenocytes
偶联
Unconjugated
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 6.0
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃(1-2周);长期储存-20℃(24个月);收货后建议分装,避免反复冻融.
图片
Recombinant CD24 Antibody (Ab222913) - Flow Cytometry Flow Cytometry analysis of C57BL/6 Mouse splenocytes labelling CD24 with Recombinant CD24 Antibody (Ab222913) (right panel) at 1.0 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Ab141774) (left panel) and detected with AF 647 - conjugated affinipure goat anti-Rat IgG.
Recombinant CD24 Antibody (Ab222913) - Flow Cytometry Flow Cytometry analysis of C57BL/6 Mouse splenocytes labelling CD24 (red) with Recombinant CD24 Antibody (Ab222913) at 1.0 μg/mL for 1 hour at 4°C and detected with AF 647 - conjugated affinipure goat anti-Rat IgG. Blue - Rat IgG Isotype Control Antibody (Ab141774). Black - Unlabelled control, cells without incubation with primary antibody.
Recombinant CD24 Antibody (Ab222913) - SEC The purity of Recombinant CD24 Antibody (Ab222913) is more than 95% verified by HPLC.