May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity).
宿主种属
小鼠(Mouse)
特异性
Human CD24
种属反应性
人(Human)
免疫原
Human CD24
阳性对照
Flow Cytometry: Human peripheral blood lymphocytes
偶联
Unconjugated
克隆类型
重组抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 6.0
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃(1-2周);长期储存-20℃(24个月);收货后建议分装,避免反复冻融.
图片
Recombinant CD24 Antibody (Ab222919) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphcytes labelling CD24 with Recombinant CD24 Antibody (Ab222919) (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Mouse IgG Isotype Control Antibody (Ab170221) (left panel) and detected with AF 488-conjugated affinipure goat anti-Mouse IgG.
Recombinant CD24 Antibody (Ab222919) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphcytes labelling CD24 (red) with Recombinant CD24 Antibody (Ab222919) at 0.2 μg/mL for 1 hour at 4°C, and detected with AF 488-conjugated affinipure goat anti-Mouse IgG. Blue - Mouse IgG Isotype Control Antibody (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
Recombinant CD24 Antibody (Ab222919) - SEC The purity of Recombinant CD24 Antibody (Ab222919) is more than 95% verified by HPLC.