Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity).
In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
宿主种属
小鼠(Mouse)
特异性
Human Galectin 3
种属反应性
人(Human)
免疫原
Recombinant full length protein corresponding human Galectin 3
Galectin 3 Mouse mAb (Ab225229) - Western Blot All lanes: Galectin 3 Mouse Antibody (Ab225229) at 1/10000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 26 kDa Observed band size: 30 kDa Exposure time: 92.1 s
ZJ25F0825654
危险品化学品经营许可证（带存储）