Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
宿主种属
兔(Rabbit)
特异性
GOPC
种属反应性
人(Human),小鼠(Mouse)
免疫原
A synthetic peptide derived from human GOPC (AA 1-80).
阳性对照
WB: HeLa, Hep G2, HEK293, THP-1, NIH/3T3 and C6 cell lysates.
偶联
Unconjugated
克隆类型
重组抗体
Format
Whole IgG
纯化方法
Protein A purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.4
防腐剂
No
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
图片
Recombinant GOPC Antibody (Ab337945) - Western Blot
All lanes: Recombinant GOPC Antibody (Ab337945) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 51 kDa
Observed band size: 56 kDa
Exposure time: 112.0 s
Recombinant GOPC Antibody (Ab337945) - Western Blot
All lanes use Recombinant GOPC Antibody (Ab337945) at 1/1000 dilution for 1 hour at room temperature.
ZJ26F0737498
危险品化学品经营许可证（带存储）