计算溶液所需的质量、体积或浓度。
提供 ≥99% 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
BRD7586 is a cell-permeable small-molecule inhibitor of SpCas9. BRD7586 is the smallest known anti-CRISPR.
In Vitro
BRD7586 specifically engages SpCas9 but not Cas12a in cells. BRD7586 (0-20 μM; 24 h) dose-dependently inhibits SpCas9 in the HiBiT-knock-in assay in HEK293T cells. BRD7586 (20 μM; 48 h) enhances the ratio of on-target versus off-target in HEK293T cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid