Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make antibody agent conjugate (ADC)
In Vitro
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be conjugated to an anti-c-Met antibody to form an anti-c-Met topoisomerase 1 Inhibitorsantibody drug conjugate (ADC). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:Drug-Linker Conjugates for ADC
规格
别名
Br-Val-Ala-NH2-双环[1.1.1]戊烷-7-MAD-MDCPT
英文别名
ABBV-969 Payload
规格或纯度
Moligand™, ≥98%
英文名称
Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT
生化机理
Br-Val-Ala-NH2-双环[1.1.1]戊烷-7-MAD-MDCPT(式 V)是一种药剂-连接体共轭物,由一种强效拓扑异构酶 I 抑制剂和一种连接体组成,可制成抗体药剂共轭物(ADC)。