BMSpep-57 hydrochloride

CAS: B659281 货号: B659281 分子式: C89H127ClN24O19S 分子量: 1904.63
有货
级别和纯度: ≥99%
别名
BMSpep-57 盐酸盐
储存条件
干燥,-80℃储存
运输条件
特低温运输
★
规格
库存
价格
数量
1mg
B659281-1mg
期货 Stock Image
¥8,000.90
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概述


BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hy

Appearance:Solid

IC50& Target:IC50: 7.68 nM (PD-1/PD-L1 interaction)

In Vitro:In a ELISA competition assay, BMSpep-57 inhibits PD-1/PD-L1 binding up to 98.1% 300 nM. And it shows a concentration dependent inhibition of PD-1/PD-L1 binding with an IC 50 of 7.68 nM. BMSpep-57 induced high levels of IL-2 at 1 µM and 500 nM concent

Biological Activity:BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC 50 of 7.68u2009nM. BMSpep-57 hydrochloride binds to PD-L1 with K d s of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-5

规格

别名
BMSpep-57 盐酸盐
规格或纯度
≥99%
英文名称
BMSpep-57 hydrochloride
储存条件
干燥,-80℃储存
运输条件
特低温运输
作用类型
抑制剂
纯度
≥99%
名称和识别符
分子类型
小分子
分子量
1904.63

高级数据

质检证书(CoA,COO,BSE/TSE 和分析图谱)
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