浏览与细胞周期调控及DNA损伤通路相关的小分子，用于肿瘤学研究、检查点研究及检测方法开发。利用本分类比较与增殖调控、修复机制及应激反应信号传导相关的化合物。
细胞周期/DNA损伤
按类别选购
ATM/ATR ATM/ATR
95Aurora激酶 Aurora Kinase
153检查点激酶 (Chk) Checkpoint Kinase (Chk)
71CRISPR/Cas9 CRISPR/Cas9
26细胞周期蛋白G相关激酶 (GAK) Cyclin G-associated Kinase (GAK)
16DNA烷化剂/交联剂 DNA Alkylator/Crosslinker
161DNA/RNA合成 DNA/RNA Synthesis
1,578DNA-PK DNA-PK
68E2F转录因子 Early 2 Factor (E2F)
4真核起始因子 (eIF) Eukaryotic Initiation Factor (eIF)
82Haspin激酶 Haspin Kinase
16LIM激酶 (LIMK) LIM Kinase (LIMK)
35微管蛋白/微管 Microtubule/Tubulin
627核苷抗代谢物/类似物 Nucleoside Antimetabolite/Analog
1,628Polo样激酶 (PLK) Polo-like Kinase (PLK)
86聚(ADP-核糖)糖水解酶 (PARG) Poly(ADP-ribose) Glycohydrolase (PARG)
19Sirtuin Sirtuin
234SWI/SNF复合物 SWI/SNF Complex
6产品列表
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![1-[4-({4-[(5-cyclopentyl-1H-pyrazol-3-yl)imino]-1,4-dihydropyrimidin-2-yl}amino)phenyl]-3-[3-(trifluoromethyl)phenyl]urea](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/C/9/C999380.jpg)
1-[4-({4-[(5-cyclopentyl-1H-pyrazol-3-yl)imino]-1,4-dihydropyrimidin-2-yl}amino)phenyl]-3-[3-(trifluoromethyl)phenyl]ureaCAS: 1639009-81-6 分子式: C26H25F3N8O 分子量: 522.500期货 货号: C999380查看产品价格与包装技术标识符
- IUPAC名称
- 1-[4-[[4-[(5-cyclopentyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
- SMILES
- C1CCC(C1)C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC=C(C=C4)NC(=O)NC5=CC=CC(=C5)C(F)(F)F
- InChIKey
- GBMIFBVLJSCVJT-UHFFFAOYSA-N
- InChI
- 1S/C26H25F3N8O/c27-26(28,29)17-6-3-7-20(14-17)33-25(38)32-19-10-8-18(9-11-19)31-24-30-13-12-22(35-24)34-23-15-21(36-37-23)16-4-1-2-5-16/h3,6-16H,1-2,4-5H2,(H2,32,33,38)(H3,30,31,34,35,36,37)
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(2s)-3-(Biphenyl-4-Yl)-2-(Biphenyl-4-Yloxy)propanoic AcidCAS: 2252488-69-8 化合物 CID: 73167563期货 货号: S935649查看产品价格与包装技术标识符
- IUPAC名称
- (2S)-2-(4-phenylphenoxy)-3-(4-phenylphenyl)propanoic acid
- SMILES
- C1=CC=C(C=C1)C2=CC=C(C=C2)CC(C(=O)O)OC3=CC=C(C=C3)C4=CC=CC=C4
- InChIKey
- DGMLYRGMJHVKNC-SANMLTNESA-N
- InChI
- 1S/C27H22O3/c28-27(29)26(19-20-11-13-23(14-12-20)21-7-3-1-4-8-21)30-25-17-15-24(16-18-25)22-9-5-2-6-10-22/h1-18,26H,19H2,(H,28,29)/t26-/m0/s1
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![1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/H/1/H1073604.jpg)
1-[4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dioneCAS: 16053-52-4 化合物 CID: 1134期货 货号: H1073604查看产品价格与包装技术标识符
- IUPAC名称
- 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
- SMILES
- CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)O
- InChIKey
- IQFYYKKMVGJFEH-UHFFFAOYSA-N
- InChI
- 1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)
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(+/-)-9-hydroxy-5Z,7E,11Z,14Z,17Z-eicosapentaenoic acidCAS: 286390-03-2 化合物 CID: 16061129期货 货号: H1226153查看产品价格与包装技术标识符
- IUPAC名称
- (5Z,7E,11Z,14Z,17Z)-9-hydroxyicosa-5,7,11,14,17-pentaenoic acid
- SMILES
- CCC=CCC=CCC=CCC(C=CC=CCCCC(=O)O)O
- InChIKey
- OXOPDAZWPWFJEW-IMCWFPBLSA-N
- InChI
- 1S/C20H30O3/c1-2-3-4-5-6-7-8-10-13-16-19(21)17-14-11-9-12-15-18-20(22)23/h3-4,6-7,9-11,13-14,17,19,21H,2,5,8,12,15-16,18H2,1H3,(H,22,23)/b4-3-,7-6-,11-9-,13-10-,17-14+
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15-keto-prostaglandin E2期货 货号: K1065620查看产品价格与包装技术标识符
- IUPAC名称
- (Z)-7-[(1R,2R,3R)-3-hydroxy-5-oxo-2-[(E)-3-oxooct-1-enyl]cyclopentyl]hept-5-enoic acid
- SMILES
- CCCCCC(=O)C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O
- InChIKey
- YRTJDWROBKPZNV-KMXMBPPJSA-N
- InChI
- 1S/C20H30O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,16-17,19,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t16-,17-,19-/m1/s1
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2'-Chloro-2'-deoxyadenosineCAS: 2627-62-5 化合物 CID: 100327期货 货号: C996024查看产品价格与包装技术标识符
- IUPAC名称
- (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-ol
- SMILES
- C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)Cl)N
- InChIKey
- ADXUXRNLBYKGOA-QYYRPYCUSA-N
- InChI
- 1S/C10H12ClN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1
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2,4-dioxo-N-(4-(pyridin-3-yloxy)phenyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide期货 货号: D1330146查看产品价格与包装技术标识符
- IUPAC名称
- 2,4-dioxo-N-(4-pyridin-3-yloxyphenyl)-1H-quinazoline-6-sulfonamide
- SMILES
- C1=CC(=CN=C1)OC2=CC=C(C=C2)NS(=O)(=O)C3=CC4=C(C=C3)NC(=O)NC4=O
- InChIKey
- CNILPKOOBRBNEQ-UHFFFAOYSA-N
- InChI
- 1S/C19H14N4O5S/c24-18-16-10-15(7-8-17(16)21-19(25)22-18)29(26,27)23-12-3-5-13(6-4-12)28-14-2-1-9-20-11-14/h1-11,23H,(H2,21,22,24,25)
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2'-Azido-2'-deoxycytidine期货 货号: A1339046查看产品价格与包装技术标识符
- IUPAC名称
- 4-amino-1-[(2R,3R,4S,5R)-3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- SMILES
- C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)N=[N+]=[N-]
- InChIKey
- FEOYKPQEERVCAV-XVFCMESISA-N
- InChI
- 1S/C9H12N6O4/c10-5-1-2-15(9(18)12-5)8-6(13-14-11)7(17)4(3-16)19-8/h1-2,4,6-8,16-17H,3H2,(H2,10,12,18)/t4-,6-,7-,8-/m1/s1
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![(9,10,18-Trihydroxy-12,12-dimethyl-6-methylidene-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-15-yl) acetate](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/T/1/T1240643.jpg)
(9,10,18-Trihydroxy-12,12-dimethyl-6-methylidene-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-15-yl) acetateCAS: 28957-08-6 化合物 CID: 429192期货 货号: T1240643查看产品价格与包装技术标识符
- IUPAC名称
- (9,10,18-trihydroxy-12,12-dimethyl-6-methylidene-7-oxo-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-15-yl) acetate
- SMILES
- CC(=O)OC1CCC(C2C13COC(C2O)(C45C3CCC(C4O)C(=C)C5=O)O)(C)C
- InChIKey
- DJQLJZNVICMJRV-UHFFFAOYSA-N
- InChI
- 1S/C22H30O7/c1-10-12-5-6-13-20-9-28-22(27,21(13,16(10)24)17(12)25)18(26)15(20)19(3,4)8-7-14(20)29-11(2)23/h12-15,17-18,25-27H,1,5-9H2,2-4H3
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(3R,4S,5S)-tert-butyl 4-(((benzyloxy)carbonyl)amino)-3-hydroxy-5-methylheptanoate期货 货号: R1242327查看产品价格与包装技术标识符
- IUPAC名称
- tert-butyl (3R,4S,5S)-3-hydroxy-5-methyl-4-(phenylmethoxycarbonylamino)heptanoate
- SMILES
- CCC(C)C(C(CC(=O)OC(C)(C)C)O)NC(=O)OCC1=CC=CC=C1
- InChIKey
- AZTSBAWJROLRIQ-LESCRADOSA-N
- InChI
- 1S/C20H31NO5/c1-6-14(2)18(16(22)12-17(23)26-20(3,4)5)21-19(24)25-13-15-10-8-7-9-11-15/h7-11,14,16,18,22H,6,12-13H2,1-5H3,(H,21,24)/t14-,16+,18-/m0/s1
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![(2S,3R,5S)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/S/1/S1038122.jpg)
(2S,3R,5S)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol期货 货号: S1038122查看产品价格与包装技术标识符
- IUPAC名称
- (2S,3R,5S)-5-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)oxolan-3-ol
- SMILES
- C1C(C(OC1N2C=C(C3=C(N=CN=C32)N)I)CO)O
- InChIKey
- LIIIRHQRQZIIRT-CSMHCCOUSA-N
- InChI
- 1S/C11H13IN4O3/c12-5-2-16(8-1-6(18)7(3-17)19-8)11-9(5)10(13)14-4-15-11/h2,4,6-8,17-18H,1,3H2,(H2,13,14,15)/t6-,7+,8+/m1/s1
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(10E,12E)-9-oxooctadeca-10,12-dienoic acidCAS: 54232-58-5 化合物 CID: 5283011期货 货号: E1052284查看产品价格与包装技术标识符
- IUPAC名称
- (10E,12E)-9-oxooctadeca-10,12-dienoic acid
- SMILES
- CCCCCC=CC=CC(=O)CCCCCCCC(=O)O
- InChIKey
- LUZSWWYKKLTDHU-SIGMCMEVSA-N
- InChI
- 1S/C18H30O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6+,14-11+
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最后更新：2026年11月5日
选择细胞周期/DNA损伤时应比较哪些方面？
在细胞周期/DNA损伤分类中，需比较来源与表达系统、纯度及其检测方法、比活性和缓冲液组成。在灵敏度较高的实验中，缓冲液的影响可能与蛋白本身同样重要。
应该从哪个细胞周期/DNA损伤子类别开始？
细胞周期/DNA损伤分为抗叶酸剂、APC、ATF6、ATM/ATR、Aurora激酶等，另有48个子类别。建议按您所处的实验流程环节选择，而非按分子类型——多数流程会用到不止一个子类别的产品。
订购细胞周期/DNA损伤前应查看哪些质量数据？
请查阅该细胞周期/DNA损伤产品批次专属分析证书中的纯度、活性和内毒素数据，并确认缓冲液及是否含载体蛋白。若计划进行下游标记或偶联，建议明确选择无载体（carrier-free）剂型。所有产品仅供专业研发用途，不得用于人体、动物、诊断或治疗。
细胞周期/DNA损伤可提供哪些文件资料？
各细胞周期/DNA损伤产品页面均提供说明书和批次专属分析证书，涵盖纯度、活性和储存信息。如需批次预留、大包装或页面未展示的文件，请联系 compliance@aladdinsci.com。
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