浏览与细胞周期调控及DNA损伤通路相关的小分子，用于肿瘤学研究、检查点研究及检测方法开发。利用本分类比较与增殖调控、修复机制及应激反应信号传导相关的化合物。
细胞周期/DNA损伤
按类别选购
ATM/ATR ATM/ATR
95Aurora激酶 Aurora Kinase
153检查点激酶 (Chk) Checkpoint Kinase (Chk)
71CRISPR/Cas9 CRISPR/Cas9
26细胞周期蛋白G相关激酶 (GAK) Cyclin G-associated Kinase (GAK)
16DNA烷化剂/交联剂 DNA Alkylator/Crosslinker
161DNA/RNA合成 DNA/RNA Synthesis
1,578DNA-PK DNA-PK
68E2F转录因子 Early 2 Factor (E2F)
4真核起始因子 (eIF) Eukaryotic Initiation Factor (eIF)
82Haspin激酶 Haspin Kinase
16LIM激酶 (LIMK) LIM Kinase (LIMK)
35微管蛋白/微管 Microtubule/Tubulin
627核苷抗代谢物/类似物 Nucleoside Antimetabolite/Analog
1,628Polo样激酶 (PLK) Polo-like Kinase (PLK)
86聚(ADP-核糖)糖水解酶 (PARG) Poly(ADP-ribose) Glycohydrolase (PARG)
19Sirtuin Sirtuin
234SWI/SNF复合物 SWI/SNF Complex
6产品列表
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![4-Oxo-1,4-dihydrobenzo[h]quinoline-3-carboxylic acid](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/O/1/O1369142.jpg)
4-Oxo-1,4-dihydrobenzo[h]quinoline-3-carboxylic acid期货 货号: O1369142查看产品价格与包装技术标识符
- IUPAC名称
- 4-oxo-1H-benzo[h]quinoline-3-carboxylic acid
- SMILES
- C1=CC=C2C(=C1)C=CC3=C2NC=C(C3=O)C(=O)O
- InChIKey
- QGOKEDVMXJBTAR-UHFFFAOYSA-N
- InChI
- 1S/C14H9NO3/c16-13-10-6-5-8-3-1-2-4-9(8)12(10)15-7-11(13)14(17)18/h1-7H,(H,15,16)(H,17,18)
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![5-(4-Methylphenyl)-4-pyrrolidin-1-ylthieno[2,3-d]pyrimidine](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/M/1/M1311454.jpg)
5-(4-Methylphenyl)-4-pyrrolidin-1-ylthieno[2,3-d]pyrimidineCAS: 342595-74-8 化合物 CID: 693939期货 货号: M1311454查看产品价格与包装技术标识符
- IUPAC名称
- 5-(4-methylphenyl)-4-pyrrolidin-1-ylthieno[2,3-d]pyrimidine
- SMILES
- CC1=CC=C(C=C1)C2=CSC3=NC=NC(=C23)N4CCCC4
- InChIKey
- VOAWQTDHSSKEKA-UHFFFAOYSA-N
- InChI
- 1S/C17H17N3S/c1-12-4-6-13(7-5-12)14-10-21-17-15(14)16(18-11-19-17)20-8-2-3-9-20/h4-7,10-11H,2-3,8-9H2,1H3
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![5-(3-Hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/H/1/H1352700.jpg)
5-(3-Hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one期货 货号: H1352700查看产品价格与包装技术标识符
- IUPAC名称
- 2-(3-hydroxyphenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one
- SMILES
- C1CCC2=C(C1)C3=C(S2)N=C(NC3=O)C4=CC(=CC=C4)O
- InChIKey
- YEBWEMIJOWUBEM-UHFFFAOYSA-N
- InChI
- 1S/C16H14N2O2S/c19-10-5-3-4-9(8-10)14-17-15(20)13-11-6-1-2-7-12(11)21-16(13)18-14/h3-5,8,19H,1-2,6-7H2,(H,17,18,20)
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5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamideCAS: 1314118-92-7 分子式: C27H25ClN4O2 分子量: 473期货 货号: C1352055查看产品价格与包装技术标识符
- IUPAC名称
- 5-(4-chlorophenyl)-N-(4-piperazin-1-ylphenyl)-N-(pyridin-2-ylmethyl)furan-2-carboxamide
- SMILES
- C1CN(CCN1)C2=CC=C(C=C2)N(CC3=CC=CC=N3)C(=O)C4=CC=C(O4)C5=CC=C(C=C5)Cl
- InChIKey
- LIPNXDIBECKOMJ-UHFFFAOYSA-N
- InChI
- 1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2
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5-Ethyluridine期货 货号: E1345591查看产品价格与包装技术标识符
- IUPAC名称
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethylpyrimidine-2,4-dione
- SMILES
- CCC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
- InChIKey
- LNVBVDVUTCPLIZ-FDDDBJFASA-N
- InChI
- 1S/C11H16N2O6/c1-2-5-3-13(11(18)12-9(5)17)10-8(16)7(15)6(4-14)19-10/h3,6-8,10,14-16H,2,4H2,1H3,(H,12,17,18)/t6-,7-,8-,10-/m1/s1
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![5-(3,4-Dimethoxyphenyl)-2-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/D/1/D1016058.jpg)
5-(3,4-Dimethoxyphenyl)-2-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidineCAS: 883003-62-1 化合物 CID: 2823337期货 货号: D1016058查看产品价格与包装技术标识符
- IUPAC名称
- 5-(3,4-dimethoxyphenyl)-2-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
- SMILES
- COC1=C(C=C(C=C1)C2=NC3=CC(=NN3C(=C2)C(F)(F)F)C4=CC=CS4)OC
- InChIKey
- CLFOYJSEPPNFQZ-UHFFFAOYSA-N
- InChI
- 1S/C19H14F3N3O2S/c1-26-14-6-5-11(8-15(14)27-2)12-9-17(19(20,21)22)25-18(23-12)10-13(24-25)16-4-3-7-28-16/h3-10H,1-2H3
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5'-O-DMT-rICAS: 119898-59-8 化合物 CID: 135497173期货 货号: O1313714查看产品价格与包装技术标识符
- IUPAC名称
- 9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-1H-purin-6-one
- SMILES
- COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=NC6=C5N=CNC6=O)O)O
- InChIKey
- PQXVLEMIGAJLIN-BQOYKFDPSA-N
- InChI
- 显示更多
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![4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4-azatricyclo[5.2.1.0^{2,6}]dec-8-ene-3,5-dione](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/D/1/D1305670.jpg)
4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-4-azatricyclo[5.2.1.0^{2,6}]dec-8-ene-3,5-dioneCAS: 301298-87-3 分子式: C20H19N3O3 分子量: 349.4期货 货号: D1305670查看产品价格与包装技术标识符
- IUPAC名称
- 4-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
- SMILES
- CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N3C(=O)C4C5CC(C4C3=O)C=C5
- InChIKey
- QOOKFECIGXERRL-UHFFFAOYSA-N
- InChI
- 1S/C20H19N3O3/c1-11-17(20(26)23(21(11)2)14-6-4-3-5-7-14)22-18(24)15-12-8-9-13(10-12)16(15)19(22)25/h3-9,12-13,15-16H,10H2,1-2H3
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![4-(2,4-Dichlorophenyl)-1,4-dihydro[1,3,5]triazino[1,2-a]benzimidazol-2-amine](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/D/1/D1328168.jpg)
4-(2,4-Dichlorophenyl)-1,4-dihydro[1,3,5]triazino[1,2-a]benzimidazol-2-amineCAS: 305343-00-4 化合物 CID: 4186742期货 货号: D1328168查看产品价格与包装技术标识符
- IUPAC名称
- 4-(2,4-dichlorophenyl)-1,4-dihydro-[1,3,5]triazino[1,2-a]benzimidazol-2-amine
- SMILES
- C1=CC=C2C(=C1)N=C3N2C(N=C(N3)N)C4=C(C=C(C=C4)Cl)Cl
- InChIKey
- NFLCLMQFIWHNOP-UHFFFAOYSA-N
- InChI
- 1S/C15H11Cl2N5/c16-8-5-6-9(10(17)7-8)13-20-14(18)21-15-19-11-3-1-2-4-12(11)22(13)15/h1-7,13H,(H3,18,19,20,21)
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![4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone hydrochloride](https://www.aladdin-e.com/media/catalog/product/cache/16359f9c8ddfa823fcb5503b1e11b7ae/A/1/A1325626.jpg)
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-2-pyrimidinone hydrochloride期货 货号: A1325626查看产品价格与包装技术标识符
- IUPAC名称
- 4-amino-1-[(2S,4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride
- SMILES
- C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl
- InChIKey
- OKKDEIYWILRZIA-DNSZWREKSA-N
- InChI
- 1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6+,7+;/m1./s1
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4,4a,4b,5,6,7,8,8a,9,10-decahydro-4b,8-dimethyl-2-(1-methylethyl)-3H-3,10a-ethanophenanthrene-8,11,12-tricarboxylic acidCAS: 730960-98-2 化合物 CID: 249748期货 货号: A1245834查看产品价格与包装技术标识符
- IUPAC名称
- 5,9-dimethyl-16-propan-2-yltetracyclo[10.2.2.01,10.04,9]hexadec-15-ene-5,13,14-tricarboxylic acid
- SMILES
- CC(C)C1=CC23CCC4C(C2CC1C(C3C(=O)O)C(=O)O)(CCCC4(C)C(=O)O)C
- InChIKey
- PXYRCOIAFZBLBN-UHFFFAOYSA-N
- InChI
- 1S/C24H34O6/c1-12(2)14-11-24-9-6-15-22(3,7-5-8-23(15,4)21(29)30)16(24)10-13(14)17(19(25)26)18(24)20(27)28/h11-13,15-18H,5-10H2,1-4H3,(H,25,26)(H,27,28)(H,29,30)
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4-Thio-2'-deoxyuridine期货 货号: T1326011查看产品价格与包装技术标识符
- IUPAC名称
- 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one
- SMILES
- C1C(C(OC1N2C=CC(=S)NC2=O)CO)O
- InChIKey
- PHNDUXLWAVSUAL-SHYZEUOFSA-N
- InChI
- 1S/C9H12N2O4S/c12-4-6-5(13)3-8(15-6)11-2-1-7(16)10-9(11)14/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,16)/t5-,6+,8+/m0/s1
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最后更新：2026年11月5日
选择细胞周期/DNA损伤时应比较哪些方面？
在细胞周期/DNA损伤分类中，需比较来源与表达系统、纯度及其检测方法、比活性和缓冲液组成。在灵敏度较高的实验中，缓冲液的影响可能与蛋白本身同样重要。
应该从哪个细胞周期/DNA损伤子类别开始？
细胞周期/DNA损伤分为抗叶酸剂、APC、ATF6、ATM/ATR、Aurora激酶等，另有48个子类别。建议按您所处的实验流程环节选择，而非按分子类型——多数流程会用到不止一个子类别的产品。
订购细胞周期/DNA损伤前应查看哪些质量数据？
请查阅该细胞周期/DNA损伤产品批次专属分析证书中的纯度、活性和内毒素数据，并确认缓冲液及是否含载体蛋白。若计划进行下游标记或偶联，建议明确选择无载体（carrier-free）剂型。所有产品仅供专业研发用途，不得用于人体、动物、诊断或治疗。
细胞周期/DNA损伤可提供哪些文件资料？
各细胞周期/DNA损伤产品页面均提供说明书和批次专属分析证书，涵盖纯度、活性和储存信息。如需批次预留、大包装或页面未展示的文件，请联系 compliance@aladdinsci.com。
危险品化学品经营许可证（带存储）