计算溶液所需的质量、体积或浓度。
为什么选择此级别
，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 6 篇同行评审文献引用。
概述
味稍甜而后微苦。有吸湿性。对光敏感。溶于水、甘油和碱溶液，微溶于乙醇和丙酮，不溶于苯。5%水溶液pH7.2-8.0，在无二氧化碳的水中为8.7。生物合成辅酶A的前提物质，由于泛酸的易潮解等不稳定特性，故用钙盐作替代物。
Information
Calcium D-Panthotenate (D-Pantothenic Acid Calcium), also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.
In vitro
Pantothenic\xa0acid\xa0increases mainly the content of free\xa0glutathione, with little effect on protein-boundglutathione in human lymphoblastoic (Jurkat) cells.\xa0Pantothenic\xa0acid also increases\xa0cell\xa0respiration with pyruvate as the exogenous substrate. Pantothenic\xa0acid belongs to vitamin B group and is the building stone of coenzyme A. Pantothenic\xa0acid can be therefore infer that its beneficial effect in various kinds of cell damage by ROS is related to the increased content or stimulated biosynthesis of this coenzyme. Pantothenic\xa0acid increases the glutathione content by more than 50% and increases the GSH/GSSG ratio by approximately the same factor. Pantothenic\xa0acid\xa0and N-acetylcysteine alleviates the\xa0ultraviolet-induced decrease of glutathione content, diminished lipid peroxidation, and partly protects the\xa0cells\xa0against\xa0apoptosisproduced by\xa0ultraviolet\xa0irradiation.
In vivo
Pantothenic acid-treated rats exhibited higher basal levels of corticosterone and progesterone than control rats in Adrenal cells. The response of ACTH and/or PRL on corticosterone and progesterone release is higher in the pantothenic acid-treated rats than in the control rats. Pantothenic acid supplementation stimulates the ability of adrenal cells in male rats to secrete corticosterone and progesterone. Pantothenic acid supplementation induces adrenalhyperresponsiveness to ACTH stimulation, and PRL further stimulated adrenal sensitivity to ACTH. Pantothenic acid prior to valproic acid (VPA) significantly protects against VPA-induced neural tube defects (NTDs) in CD-1mice. Pantothenic acid prevents VPA-induced alterations in NF-kappaB, Pim-1, and c-Myb in CD-1 mice.
Cell Data
cell lines：
Concentrations：
Incubation Time：
Powder Purity:
规格
英文别名
D-Pantothenic Acid Calcium | N-[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]-β-alanine,calcium salt (2:1)
规格或纯度
10mM in DMSO
英文名称
Calcium D-Panthotenate
生化机理
D-泛酸钙（D-泛酸钙）又称维生素 B5 钙，是一种水溶性维生素，也是许多动物的必需营养素。
储存条件
-80℃储存
运输条件
特低温运输
作用类型
抑制剂
名称和识别符
EC号
205-278-9
分子类型
小分子
Isomeric SMILES
CC(C)(CO)[C@H](C(=O)NCCC(=O)[O-])O.CC(C)(CO)[C@H](C(=O)NCCC(=O)[O-])O.[Ca+2]
分子量
476.54
Beilstein号
4(3)1286
Reaxy-Rn
4049460
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4049460&ln=
技术文档
高级数据
化学和物理性质
比旋光度
27 ° (C=5, H2O)
熔点
195-196°C
安全和危险性（GHS）
RTECS
RU4375000
Merck Index
7015
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
技术文档和文章
此产品的引用文献
溶液计算器
产品仅提供给经过验证的企业、机构和合格的专业人员用于研发。不适用于人类、动物、诊断或治疗。
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