计算溶液所需的质量、体积或浓度。
CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity
Appearance:Solid
IC50& Target:CRBN-DDB1 490 nM (IC 50 )
In Vitro:CCT367766 formic (50-1500 nM; 24 hours) demonstates the depletion of pirin protein as a the time-dependent hook-effect in SK-OV-3 human ovarian cancer cells. CCT367766 formic (0.5-50 nM; 2 hours) demonstrates the concentration-dependent depletion of
Biological Activity:CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity