CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits T reg cell development.
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In Vitro:CMD178 TFA (100 μM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells. CMD178 TFA (100 μM) inhibits the development of T reg cells induced by IL2/sIL-2Rα signaling. MCE has not independently confirmed the acc
Biological Activity:CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits T reg cell development.