Product Description
Diacylglycerol pyrophosphate (DGPP), involved in a novel signaling pathway, has been found in plants, Saccharomyces cerevisiae, and Escherichia coli and macrophage-activating factor, and suggests a potential role for this compound in triggering homeostatic cellular responses.Biological Applications: Short chain DGPP (DiC8) DiC8 DGPP is added to a test tube as a chloroform solution and the solvent is removed. Add water or buffer to the dry lipid residue followed by sonication. The solution is added to cells directly. The short chain DGPP is taken up by mammalian cells and by yeast. Long chain DGPP (DiC18:1) DiC18:1 DGPP is added to a test tube as a chloroform solution and the solvent is removed. Add 0.5% Tergitol (detergent) solution and add this to cells.Notes:Biological Application — "I am not sure how well the long chain DGPP is taken up in yeast cells, that is why we synthesized the DiC8 compound. We only use the long chain compound as a standard for TLC, HPLC and for DGPP phosphatase assays".Storage Conditions — "Store concentrated, ~25mg/ml in chloroform. Concentrations below 10mg/ml are not as stable".Personal communication, George M. Carman, Sept. 1999 Dioleoylglycerophosphate (DGPP) is mainly present in plants and yeast. It carries two phosphate groups in its headgroup. DGPP 18:1 (dioleoylglycerol pyrophosphate) has two oleyl chains and is a bioactive lipid. Product Application DGPP 18:1 (dioleoylglycerol pyrophosphate) may be used in biochemical assays to study its effects on transient receptor potential 1 (TRPV1) function. It may also be used in liposome binding studies.

规格

英文别名

diammonium 1,2-dioleoyl-sn-glyceropyrophosphate | Dioleoyl Diacylglycerol Pyrophosphate | 1,2-Dioleoyl-sn-glycero-pyrophosphate (ammonium salt) | Dioleoylglycerol pyrophosphate | diammonium (2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl hydrogen diphosphate | 18:1 DGPP, dioleoylglycerol pyrophosphate (ammonium salt), powder | diazanium;[[(2R 展开

规格或纯度

≥99%

英文名称

dioleoylglycerol pyrophosphate (ammonium salt)

生化机理

二油酰甘油磷酸酯（DGPP）能够刺激植物的胁迫相关反应。它还可能在脱落酸（ABA）信号传导中发挥作用。

储存条件

-20°C储存

运输条件

超低温运输

纯度

≥99%

名称和识别符

PubChem SID

528773149

分子类型

小分子

IUPAC Name

diazanium;[[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-oxidophosphoryl] hydrogen phosphate

INCHI

1S/C39H74O11P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)47-35-37(36-48-52(45,46)50-51(42,43)44)49-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;;/h17-20,37H,3-16,21-36H2,1-2H3,(H,45,46)(H2,42,43,44);2*1H3/b19-17-,20-18-;;/t37-;;/m1../s1

InChi Key

SIWIEYLZDXPRIY-AXQFFRRZSA-N

Smiles

CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)([O-])OP(=O)(O)[O-])OC(=O)CCCCCCCC=CCCCCCCCC.[NH4+].[NH4+]

Isomeric SMILES

CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OP(=O)(O)[O-])OC(=O)CCCCCCC/C=C\CCCCCCCC.[NH4+].[NH4+]

PubChem CID

24978513

分子量

815.01