Dextran sulfate can interact and bind to lipids making it useful in protein isolation techniques to remove contaminating lipid molecules Dextran sulfate is supplied as a white powder which dissolves freely in water or salt solutions giving a clearsolution.Dextran sulfates may be produced with a wide range of molecular weights and degrees of sulfation. Each of the products within this range is supplied with sulphur contents of 16-20%. Dextran sulfates act as potent polyanions and offer many interesting pharmacological and biophysical properties. Dextran sulfates are produced by sulfating selected dextran fractions. The dextran sulfate is supplied as the sodium salt and is stabilised by a small addition of phosphate salts. A certificate of analysis is supplied with each batch. The molecular weight range, sulfur content, moisture etc. are carefully controlled. Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of sidechains linked to the 3-carbon of glucose. Dextran sulfate is a sulfated derivative of selected dextran fraction.
Dextran sulfate have a wide range of applications areas and properties. Some examples are:Anti-coagulation agent in cell media Selective precipitation of lipoproteins Acceleration of DNA hybridisation.Releasing DNA from DNA-histones complexesInhibition tRNA-binding to ribosomes Inhibition of ribonucleasesAnti-viral propertiesUsed in cosmetics for anti-inflammation properties and osmotic retention of water Separation of microorganisms and macromolecules Adjuvant in vaccines Studies of perm selectivity of membranes.
SKU
NAME
Molecular Weight
D1524769-5K
Dextran sulfate sodium salt(DSS)
5000
规格
规格或纯度
BioReagent
英文名称
Dextran sulfate sodium salt(DSS)
生化机理
葡聚糖硫酸钠通过与结肠中链脂肪酸结合并诱导炎症，在小鼠和大鼠体内引发结肠炎。
应用
Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.
危险品化学品经营许可证（带存储）