计算溶液所需的质量、体积或浓度。
为什么选择此级别
提供 ≥98% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
2-8°C储存,干燥。低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
DDO-2093 dihydrochloride is a potent MLL1-WDR5 protein-protein interaction inhibitor ( IC 50 =8.6 nM; K d =11.6 nM) with antitumor activity. DDO-2093 dihydrochloride selectively inhibits the catalytic activity of MLL complex.
Appearance:Solid
In Vitro:DDO-2093 (5 μM; pretreated 7 days) dihydrochloride inhibits MLL-fusion protein dependent genes expression ( HOXA9 and Meis1 ). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisC
In Vivo:DDO-2093 (20-80mg/kg; i.p.; every other day for 21 days) dihydrochloride significantly suppresses the tumor size and weight in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. A
Biological Activity:DDO-2093 dihydrochloride is a potent MLL1-WDR5 protein-protein interaction inhibitor ( IC 50 =8.6 nM; K d =11.6 nM) with antitumor activity. DDO-2093 dihydrochloride selectively inhibits the catalytic activity of MLL complex.
规格
别名
DDO-2093 二盐酸盐
规格或纯度
≥98%
英文名称
DDO-2093 dihydrochloride
储存条件
2-8°C储存,干燥
运输条件
低温运输
作用类型
抑制剂
纯度
≥98%
名称和识别符
分子类型
小分子
分子量
687.04
技术文档
高级数据
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
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溶液计算器
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