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BioReagent 级 ,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
EPO mRNA 编码人类促红细胞生成素(EPO)蛋白,这是一种控制红细胞生成的激素。EPO 还在伤口愈合和大脑对神经损伤的反应中发挥作用。Karikó 等人展示,在体内转染 EPO mRNA 后,网织红细胞计数和血细胞比容显著增加。EPO mRNA 作为一种模型药物,可用于研究 mRNA 药物的设计和优化策略。
本产品模拟了具有 5’Cap 1 结构和 3’poly (A) 尾巴的成熟 mRNA,能在体内、体外高效表达。
产品属性
| 产品浓度: | 1mg/mL |
| 储存溶液: | 1 mM 柠檬酸钠,pH6.5 |
| mRNA 序列全长: | 859nt |
| 完整性: | ≥85% |
| 产品纯度: | mRNA 电泳条带单一 |
| 转染效率: | 293T 细胞转染 |
运输和储存
注意事项
Storage buffer: 1 mM Sodium citrate, pH 6.5
EPO mRNA encodes human erythropoietin (EPO) protein, a hormone that regulates red blood cell production. EPO also plays a role in wound healing and the brain's response to nerve injury. Karikó et al. showed that after in vivo transfection of EPO mRNA, reticulocyte count and hematocrit increased significantly. As a model drug, EPO mRNA can be used to study the design and optimization strategies of mRNA drugs.
This product mimics mature mRNA with a 5'Cap 1 structure and a 3'poly(A) tail, and can be efficiently expressed both in vivo and in vitro.
Product Attributes
| Product Concentration: | 1mg/mL |
| Storage Solution: | 1 mM Sodium Citrate, pH6.5 |
| Full Length of mRNA Sequence: | 859nt |
| Integrity: | ≥85% |
| Product Purity: | Single mRNA Electrophoresis Band |
| Transfection Efficiency: | 293T Cell Transfection |
Transportation and Storage
Precautions
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | E1506464 |