5(6)-EET-d11在16、16',17、17',18、18',19、19',20、20和20位含有11个氘原子。它旨在用作定量5(6)-EET bcy气相色谱或液相色谱质谱(MS)的内标。5(6)-EET通过cCYP450在大鼠和兔肝微粒体中生物合成。在神经内分泌细胞中,例如垂体前叶和胰岛,5(6)-EET与Ca2 +的动员和激素分泌有关。
5(6)-EET-d11 contains 11 deuterium atoms at the 16, 16', 17, 17', 18, 18' ,19, 19' ,20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of 5(6)-EET bcy GC- or LC-mass spectrometry (MS). 5(6)-EET is biosynthesized in rat and rabbit liver microsomes by cCYP450. In neuroendocrine cells, such as the anterior pituitary and pancreatic islet, 5(6)-EET has been implicated in the mobilization of Ca2+ and hormone secretion.
(±)5(6)-EET-d11is an internal standard of 5(6)-EET bcy GC- or LC-mass spectrometry