EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from the immunocytes. EMT inhibitor-2 inhibits CYP3A4 testosteron and CYP2C9 with IC 50 s of 49.72 and 5.54 μM, respectively.
Form:Solid
规格
别名
EMT抑制剂-2
规格或纯度
≥99%
英文名称
EMT inhibitor-2
生化机理
EMT 抑制剂-2(化合物 1)可抑制免疫细胞释放的 IL-1β 和 TGF-β 等物质诱导的上皮-间质转化(EMT)。EMT 抑制剂-2 可抑制 CYP3A4 睾酮和 CYP2C9,其 IC 50 s 分别为 49.72 和 5.54 μM