Conversion of soluble fibrinogen to the insoluble fibrin is the final step in the blood coagulation cascade. Aladdin offers three types of purified fibrinogen prepared by a combination of salt precipitation, affinity chromatography and immunoaffinity chromatography methods to suit the individual researcher’s needs. All three forms are >95% clottable (by functional assays) and purity is >95% by SDS-PAGE.
Fibrinogen, Plasminogen Depleted
Fibrinogen, Plasminogen and vWF depleted
Fibrinogen, vWF, Plasminogen & Fibronectin Depleted
Extinction Coefficient (1%) = 15.1
Molecular Weight = 330,000 daltons
The Human Fibrinogen, Plasminogen, vWF and Fibronectin Depleted is homogeneous as judged on a 4-20% gradient gel and is greater than 95% clottable. The plasminogen, von Willebrand Factor and Fibronectin were depleted using affinity chromatography. Protein must be thawed in a 37℃ water bath, then aliquot and freeze the unused portion at -80℃.
The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.
Fibrinogen MUST be thawed in a 37℃ water bath. Once thawed, do not chill. Remaining protein may be aliquoted into single use size and frozen at -80℃.
规格
产品名称
纤维蛋白原，去除纤溶酶原、血管性血友病因子及纤连蛋白
规格或纯度
BioReagent, ≥95%(SDS-PAGE), from Human plasma; Protein concentration: See COA
危险品化学品经营许可证（带存储）