技术文章

(±)-1-(2-Furyl)ethanol: Properties, Handling & Lab Use

(±)-1-(2-Furyl)ethanol is a racemic secondary alcohol bearing a furan ring that serves as a versatile chiral building block and flavour-chemistry intermediate in organic synthesis research.

CAS Number
Not specified in source material — review required
Molecular Formula
C₆H₈O₂
Molecular Weight
112.13 g/mol
Appearance
Colourless to pale yellow liquid (typical for this compound class; verify with CoA)
Solubility
Miscible with common organic solvents (ethanol, diethyl ether, ethyl acetate, dichloromethane); limited water solubility
Storage Condition
Store in a cool, dry, well-ventilated location away from heat sources and incompatible oxidising agents; seal tightly
SKU
x170274

Physicochemical Properties

(±)-1-(2-Furyl)ethanol (molecular formula C₆H₈O₂, MW 112.13 g/mol) is a racemic mixture of the R- and S-enantiomers of 1-(furan-2-yl)ethanol. The compound features a furan heterocycle attached at position 1 of an ethanol backbone, giving it both aromatic character from the furan ring and the reactivity typical of secondary aliphatic alcohols.

The compound is generally a colourless to pale yellow liquid under standard conditions. It is miscible with common polar and non-polar organic solvents including ethanol, diethyl ether, dichloromethane and ethyl acetate, while its miscibility with water is limited due to the hydrophobic furan ring. Researchers should consult the certificate of analysis (CoA) supplied with each lot for confirmed purity, boiling point, refractive index and specific gravity values, as these can vary slightly between production batches.

Note: The CAS number and precise boiling point were not provided in the source material; these should be verified against the product CoA or a validated chemical database before use in protocols.

Safe Handling and Storage

As with all furan-containing organic liquids, (±)-1-(2-Furyl)ethanol should be handled with appropriate laboratory precautions. Always work in a well-ventilated fume hood to minimise inhalation of vapours. Wear chemically resistant gloves (nitrile recommended), safety glasses or goggles, and a laboratory coat during all handling operations.

Avoid contact with strong oxidising agents, strong acids and open flames. The furan ring can be susceptible to acid-catalysed ring-opening under harsh conditions, so keep the reagent away from concentrated mineral acids during storage.

For storage, keep the container tightly sealed in a cool (typically 2–8 °C or room temperature as specified on the product label), dry, and well-ventilated area away from direct sunlight and ignition sources. Consult the Safety Data Sheet (SDS) for this product for full hazard classification, first-aid measures, disposal guidance, and transport regulations before use. All local, national and institutional regulations for handling and disposal of organic solvents must be observed.

Review flag: Specific GHS hazard codes, flash point, and regulatory transport classification were not available in the source material; retrieve from the official Aladdin SDS for SKU x170274.

Laboratory Applications

(±)-1-(2-Furyl)ethanol finds application in several areas of synthetic and flavour chemistry research:

  • Chiral building block: The racemic mixture is commonly used as a substrate or starting material in asymmetric synthesis studies, including enzymatic resolution, biocatalytic kinetic resolution with lipases, and chemoenzymatic routes to enantiopure furanyl alcohols. The individual enantiomers obtained through such resolution can serve as chiral auxiliaries or intermediates in natural product synthesis.
  • Flavour and aroma chemistry: Furanyl alcohols and their esters are associated with characteristic aroma profiles in food science. (±)-1-(2-Furyl)ethanol and its derivatives are used as reference compounds or synthetic intermediates in flavour research.
  • Synthetic intermediate: The secondary hydroxyl group can be oxidised to the corresponding ketone, esterified, or subjected to other standard transformations, making this compound a versatile intermediate in multi-step organic synthesis.
  • Biotransformation studies: The compound is frequently employed as a model substrate to evaluate the stereoselectivity of oxidoreductases and hydrolases in biocatalysis research.

Review flag: Specific literature references for the above applications were not provided in the source material; citations should be added upon editorial review.

Purity, Quality and Ordering Information

Aladdin Scientific supplies (±)-1-(2-Furyl)ethanol under SKU x170274. Each shipment is accompanied by a certificate of analysis (CoA) documenting lot-specific purity and quality data. Researchers should verify that the purity grade is suitable for their intended application—higher purity grades are recommended for sensitive analytical methods or high-precision asymmetric synthesis.

For applications requiring enantiopure material, researchers should consider chiral resolution of the racemic compound using established protocols (enzymatic kinetic resolution, chiral HPLC preparative separation, or asymmetric synthesis). The racemic form supplied as x170274 is appropriate as a starting material for resolution studies or as a racemate reference standard.

For pricing, availability, bulk quantities, and current stock information, contact Aladdin Scientific directly or visit the product page. Custom purity grades or packaging may be available upon request.

Frequently asked questions

What is (±)-1-(2-Furyl)ethanol used for in the laboratory?

(±)-1-(2-Furyl)ethanol is used primarily as a chiral building block in asymmetric synthesis, as a substrate for enzymatic kinetic resolution studies, and as a synthetic intermediate in flavour chemistry research. Its secondary alcohol functionality also makes it suitable for oxidation, esterification, and other standard organic transformations.

How should (±)-1-(2-Furyl)ethanol be stored to maintain stability?

The compound should be stored in a tightly sealed container in a cool, dry, and well-ventilated location away from direct sunlight, heat sources, open flames, and strong oxidising agents. Refer to the product label and Safety Data Sheet (SDS) for lot-specific storage temperature recommendations.

Is the product supplied as a racemate or as a single enantiomer?

Aladdin Scientific supplies this product (SKU x170274) as the racemic mixture (±), containing equal amounts of the R- and S-enantiomers. Researchers requiring enantiopure material will need to perform chiral resolution using enzymatic, chromatographic, or asymmetric synthetic methods.

What solvents are compatible with (±)-1-(2-Furyl)ethanol?

(±)-1-(2-Furyl)ethanol is miscible with common organic solvents including ethanol, diethyl ether, ethyl acetate, and dichloromethane. It has limited miscibility with water due to the hydrophobic furan ring. Always verify solubility in your specific solvent system before use in sensitive applications.

Where can I find the Safety Data Sheet (SDS) for SKU x170274?

The Safety Data Sheet for (±)-1-(2-Furyl)ethanol (SKU x170274) is available through the Aladdin Scientific website on the product detail page. You may also contact Aladdin Scientific customer service to request a copy. Always consult the SDS before handling any chemical reagent.

References

  1. Aladdin Scientific product page for (±)-1-(2-Furyl)ethanol, SKU x170274. Retrieved from Aladdin Scientific catalogue.
  2. General physicochemical data for 1-(furan-2-yl)ethanol from standard chemical databases (e.g., PubChem, Reaxys). Specific values to be confirmed against lot CoA.
  3. Enzymatic resolution of furanyl alcohols using lipases: general methodology references to be added during editorial review.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.

目录: 技术文章

Da — 若无特别说明,分子量单位默认为道尔顿。   Mw — 重均分子量。   Mn — 数均分子量。

产品仅供科研与开发使用,不用于人体、动物、诊断或治疗。

引用本文

阿拉丁科学.《(±)-1-(2-Furyl)ethanol: Properties, Handling & Lab Use》. 阿拉丁知识库,更新于 2026年10月21日。 https://www.aladdin-e.com/zh_cn/faqs/pm-1-2-furyl-ethanol-properties-handling-lab-use-en.html
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