Roles of Interferon-Stimulated Genes in Antiviral Immunity: RIG-I, MDA5, IFI35, and ISG Expression Regulation
Interferon-stimulated genes (ISGs) constitute the core effector layer for establishing the cellular antiviral state. After viral RNA is recognized by pattern recognition receptors such as RIG-I and MDA5, type I/type III interferon production can be induced through MAVS, TBK1, IRF3/IRF7, and ...
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