Saturated Bioisosteres of the Benzene Ring: Design Principles, Property Evaluation, and Scaffold Selection
The benzene ring provides a stable geometry, well-defined substitution vectors, an appropriate hydrophobic surface area, and aromatic interactions. It also benefits from mature synthetic and late-stage functionalization methods. Consequently, benzene rings are widely present in drug molecules ...
危险品化学品经营许可证（带存储）