With the acceleration of population aging, age-related cancers, cardiovascular diseases, neurodegenerative diseases, and metabolic abnormalities continue to increase, making the mechanisms of aging an important direction in life science and disease research. Cellular senescence is an important ...
Lipids are not synonymous with fats. Fats mainly refer to energy-storage lipids such as triacylglycerols, whereas lipids comprise a much broader range of structural classes, including fatty acids, glycerophospholipids, sphingolipids, and sterol lipids. Different lipids participate not only in ...
Cellular senescence is a stable state of proliferative arrest induced by cellular damage or stress. Persistent accumulation of senescent cells and their senescence-associated secretory phenotype can promote chronic inflammation and tissue dysfunction, whereas senolytics selectively induce ...