1,8-Naphthyridine-Based Aldose Reductase Inhibitors: Scaffold Construction, In Vitro Inhibitory Activity, and Directions for Structural Optimization
Aldose reductase (ALR2) is a reduced nicotinamide adenine dinucleotide phosphate-dependent enzyme in the polyol pathway. The human enzyme is encoded by the aldo-keto reductase family 1 member B1 gene (AKR1B1). The molecular design of aldose reductase inhibitors (ARIs) generally requires ...
危险品化学品经营许可证（带存储）