药物如何递送?脂质纳米颗粒
mRNA、siRNA等核酸分子易受核酸酶降解、难以跨越细胞膜,并可能在内吞后滞留于内体。脂质纳米颗粒(lipid ...
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mRNA、siRNA等核酸分子易受核酸酶降解、难以跨越细胞膜,并可能在内吞后滞留于内体。脂质纳米颗粒(lipid ...
Nucleic acid molecules such as mRNA and siRNA are susceptible to nuclease degradation, cannot readily cross cell membranes, and may become trapped within endosomes after endocytosis. Lipid nanoparticles (LNPs) establish a cytosolic delivery pathway through nucleic acid encapsulation, ...
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