Kallikrein-related peptidases regulate the skin barrier, neural plasticity, vascular homeostasis, and reproductive function through limited proteolysis. Dysregulated KLK expression, activation, or inhibition can remodel the extracellular matrix and receptor signaling and contribute to tumors, ...
Proteases are widely present in cells and play a critical role in protein degradation and homeostasis regulation. However, during biochemical and molecular biology experiments, samples are susceptible to degradation by endogenous proteases during lysis or purification, which can lead to loss or ...
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