Autoantigens, Core Signaling Pathways, and Organ Damage Mechanisms in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by disruption of immune tolerance, persistent exposure of nucleic acid autoantigens, autoantibody production, and immune-complex-mediated tissue injury. Its pathology is not driven by a single immune-cell ...
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