Cell surface glycan modification research is mainly used to analyze how glycosylation structures on glycoproteins, glycolipids, and proteoglycans affect cell recognition, adhesion, migration, immune regulation, and receptor signaling. In experiments, it is not enough to detect glycan ...
Sialylation is a pivotal terminal modification of glycoproteins and glycolipids that can substantially influence charge distribution, three-dimensional presentation, receptor recognition, and in vivo clearance behavior. Sialyltransferases use CMP-activated sialic acid (cytidine ...