“Mimic” means “simulator” or “mimetic molecule.” In molecular biology experiments, a miRNA mimic usually refers to an artificially synthesized small RNA molecule used to simulate the function of an endogenous mature miRNA. Its main purpose is to enhance the functional level of a specific miRNA, ...
Small interfering RNA (siRNA) is a double-stranded RNA molecule typically 20–25 nt in length. Within the RNA interference (RNAi) pathway, siRNA directs post-transcriptional gene silencing by promoting target mRNA cleavage and degradation or by suppressing translation, thereby reducing protein ...