主题

Lysosome

用于检测、定量和定位抗原与抗体的技术——ELISA、免疫印迹、免疫组化与流式细胞术。以下是我们知识库中标注该主题的实验方案、常见问题与技术文章。

4 项资源 · 实验方案、常见问题与文章
article

LYSET: The Lysosomal Enzyme Trafficking Hub Behind Cancer Cell Survival

LYSET is an important Golgi membrane protein that maintains the correct trafficking of lysosomal enzymes by regulating GNPT and the mannose-6-phosphate pathway. Under nutrient-limited conditions, some cancer cells depend on lysosomal degradation of extracellular proteins to obtain amino acids, ...

更新于 2026年9月阅读12分钟
article

Molecular Mechanisms, Selective Degradation, and Disease Regulation of Autophagy

Autophagy is an essential lysosome-dependent quality-control process through which cells degrade and recycle intracellular material. Based on how substrates enter degradative compartments, autophagy is primarily classified into macroautophagy, microautophagy, and chaperone-mediated autophagy. ...

更新于 2026年9月阅读12分钟
article

The Role of Lysosomes in Metabolic and Autoimmune Diseases

Lysosomes are core organelles for cellular catabolism and quality control. They are responsible for degrading materials derived from intracellular autophagy, extracellular endocytosis, phagocytosis, and macropinocytosis. In addition to degradation, lysosomes participate in nutrient sensing, mTOR ...

更新于 2026年8月阅读12分钟

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常与免疫学实验一起研究的技术。