The Methodological Value of TPS-Cl: The Logic of Selective Activation and Representative Transformations in Nucleoside and Nucleotide Chemistry
The central role of 2,4,6-triisopropylbenzenesulfonyl chloride (TPS-Cl) in nucleoside and nucleotide chemistry is that it breaks down certain complex transformations into steps that are clearer and easier to control: an identifiable activated state is formed first, and subsequent nucleophiles ...
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