用于检测、定量和定位抗原与抗体的技术——ELISA、免疫印迹、免疫组化与流式细胞术。以下是我们知识库中标注该主题的实验方案、常见问题与技术文章。
“Cold” tumors are generally characterized by insufficient tumor antigen presentation, limited effector T-cell infiltration, and pronounced local immunosuppression, resulting in relatively poor responses to immune checkpoint blockade.
“冷”肿瘤通常表现为肿瘤抗原呈递不足、效应T细胞浸润缺乏及局部免疫抑制显著，对免疫检查点阻断治疗的响应相对有限；“热”肿瘤则具有较活跃的炎症反应、丰富的肿瘤浸润淋巴细胞及较完整的抗肿瘤免疫循环。
Intracellular DNA sensing is not always triggered directly by exogenous pathogens. In many noninfectious stress settings, its upstream origin is first a disruption of mitochondrial metabolic homeostasis.
细胞内DNA感知并非总由外源病原直接触发，在不少非感染性应激背景下，其上游首先是线粒体代谢稳态破坏。
常与免疫学实验一起研究的技术。
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