BioReagent 级 提供 ≥90%(HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
hsa-miR-181b-5p antagomir is a chemically modified single-stranded oligonucleotide complementary to the mature miRNA. It is fully 2'-O-methylated over the entire sequence, with 2 phosphorothioate modifications at the 5' end and 4 phosphorothioate modifications at the 3' end, and is conjugated with high‑affinity cholesterol‑TEG at the 3' terminus. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
miRBase ID: MIMAT0000257
Mature miRNA sequence: AACAUUCAUUGCUGUCGGUGGGU
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ26F0636001 |
分析证书 | H1470995 |
| ZJ26F0636000 |
分析证书 | H1470995 |
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