Homologous recombination-IN-1 is a novel RAD51-BRCA2 protein-protein interaction inhibitor ( EC 50 =19 μM). Homologous recombination-IN-1 can interfere with homologous recombination.
In Vitro
Homologous recombination-IN-1 (10-40 μM; 5 h) reduces cell homologous recombination in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: BxPC3 cells Concentration: 10-40 μM Incubation Time: 5 hours Result: Led to homologous recombination inhibition with an EC 50 value of 18.4 μM.