计算溶液所需的质量、体积或浓度。
EnzymoPure™ 级 提供 ≥95% 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
-20°C储存。超低温运输 。请查阅批次 COA 获取详细规格。
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Isovaleryl-CoA is a branched-chain acyl CoA and an intermediate in the metabolism of the essential amino acid L-leucine. It is formed from L-leucine by the branched-chain a-keto acid dehydrogenase (BCKAD) complex and is converted to 3-methylcrotonyI-CoA by isovaleryl-CoA dehydrogenase (IVD), an enzyme involved in the inbor error of metabolism isovaleric acidemia. Isovalery-CoA increases the oxidation rate of the branched-chain 2-0x0 acids 3-methyl-2-butanoate and 4-methyl-2-oxopentanoate in isolated rat muscle mitochondria in the absence of carnitine when used at a concentration of 1 mM. It also inhibits succinate-CoA ligase activity in rat liver mitochondria (IC5o = 273 μuM).
Precautions
lsovaleryl-coenzyme A (isovaleryl-CoA) (sodium salt) is supplied as a solid. A stock solution may be madeby dissolving the isovalery.-CoA (sodium salt) in water. We do not recommend storing the aqueous solutionfor more than one day.