Imlunestrant (LY-3484356) tosylate is an orally active, potent and selective estrogen receptor degrader (SERD) with pure antagonistic properties. Imlunestrant tosylate results in sustained inhibition of ER-dependent gene transcription and cell growth. Imlunestrant tosylate can be used for the research of ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC).
In Vitro
LY3484356 shows favorable pharmacokinetic (PK) properties, including antitumor activity in ESR1 mutants. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
规格
别名
免疫抑制剂甲磺酸盐
规格或纯度
≥98%
英文名称
Imlunestrant tosylate
生化机理
伊伦司琼(LY-3484356)对甲苯磺酸盐是一种具有纯粹拮抗特性的口服活性、强效和选择性雌激素受体降解剂(SERD)。对甲苯磺酸依仑司群可持续抑制 ER 依赖性基因转录和细胞生长。伊莫司群