What Is SCGB3A2 and Why Is It Studied?

SCGB3A2 (Secretoglobin Family 3A Member 2), also referred to as uteroglobin-related protein 2 (UGRP2) in some literature, is a small secreted protein belonging to the secretoglobin superfamily. It is predominantly expressed in airway epithelial cells and has been associated with lung development, innate immune modulation, and potential roles in allergic airway disease. Researchers study SCGB3A2 as a biomarker candidate and functional mediator in pulmonary biology.

Because SCGB3A2 expression is linked to airway homeostasis, antibodies against this target enable scientists to detect, localize, and quantify the protein in tissue sections, cell lysates, and other biological matrices. The Aladdin Scientific SCGB3A2 Mouse mAb (Ab351068) provides a monoclonal tool for such investigations.

Product Specifications and Formulation Details

The SCGB3A2 Mouse mAb (Ab351068) is sourced from absea (clone reference KC-1703) and is supplied in a PBS-only formulation. This means the antibody solution contains phosphate-buffered saline as the sole buffer with no added carrier proteins (such as BSA) and no stated preservative (such as sodium azide). Key implications for end users include:

• Compatibility: The absence of BSA or other carrier proteins makes this formulation suitable for direct conjugation workflows and functional assays where exogenous protein interference must be minimized.
• Preservative-free consideration: Users should confirm current lot-specific documentation for any preservative content, handle accordingly, and adhere to recommended storage conditions to maintain antibody integrity.
• Concentration and volume: Consult the product datasheet for lot-specific concentration, total volume, and recommended working dilutions, as these parameters may vary between lots.

Recommended Storage and Handling

To preserve the activity and specificity of SCGB3A2 Mouse mAb (Ab351068), follow standard monoclonal antibody storage best practices:

• Store the antibody at -20 °C for long-term storage, or at 4 °C for short-term use (typically up to four weeks), in accordance with the product datasheet.
• Avoid repeated freeze-thaw cycles, which can denature the antibody and reduce binding performance. Aliquot into single-use volumes upon first thaw.
• Because the formulation is PBS-only with no stated preservative, keep samples on ice during experimental setup and minimize prolonged exposure to room temperature.
• Centrifuge briefly before opening the vial to collect any solution from the cap or walls.

Always refer to the current lot-specific Certificate of Analysis (CoA) and product datasheet for authoritative storage instructions.

Ordering, Availability, and Support

SCGB3A2 Mouse mAb is available from Aladdin Scientific under catalog number Ab351068. To place an order or request a quotation, visit the Aladdin Scientific website product page or contact your regional sales representative. For procurement teams, bulk or custom orders may be available — please enquire via the customer service portal.

Technical support resources available to customers include:

• Lot-specific Certificates of Analysis (CoA) downloadable from the product page.
• Product datasheets detailing validated applications, recommended dilutions, and positive controls.
• Technical application support from Aladdin Scientific scientists for troubleshooting staining, blotting, or assay optimization questions.

For returns or quality concerns, please consult the Aladdin Scientific Returns and Refunds policy and retain all original packaging and documentation.