LP 12 hydrochloride hydrate is a potent and selective 5-HT7 receptor agonist with a K i of 0.13 nM. LP 12 hydrochloride hydrate displays selectivity for 5-HT7 over D2, 5-HT1A and 5-HT2A receptors ( K i values are 224 nM, 60.9 nM and >1000 nM, respectively).