A dual-mode electrochemiluminescence-electrochemical sensor based on Ru(bpy)32+@Ti3CN and Zn4Sn3O5 for highly sensitive detection of sodium saccharin

In this paper, a dual-mode electrochemiluminescence-electrochemical (ECL-EC) sensor was constructed using Ru(bpy) 3 2+ @Ti 3 CN and Zn 4 Sn 3 O 5 via multi-step amplification strategy for the detection of sodium saccharin (SS). The maximum ECL/EC initial signals were obtained by the synergistic action of Ru(bpy) 3 2+ @Ti 3 CN and Zn 4 Sn 3 O 5 in the tri-n-propylamine (TPrA) solution. Given that SS reacted with Ru(bpy) 3 2+ , the ECL/EC signal values both decreased. The relevant mechanism was investigated. Under the best optimization conditions, the ECL detection exhibited a linear range of 5.0 × 10 −15 to 5.0 × 10 −10  mol·L −1 with a limit of detection (LOD) of 1.67 × 10 −15  mol·L −1 (S/N = 3), while EC detection showed a linear range of 5.0 × 10 −9 to 5.0 × 10 −4  mol·L −1 with the LOD of 1.67 × 10 −9  mol·L −1 (S/N = 3). Satisfactory results were obtained in a variety of actual samples.