Bimetallic PdNi Synergized MOF Catalysts for Efficient One-Pot Tandem Reactions via Pickering Interface Microenvironment

The application of Pickering emulsions in interfacial catalysis provides a promising platform for biphasic reactions. Metal–organic frameworks (MOFs), owing to their high surface area, tunable porosity, and flexible functionalization, have emerged as ideal stabilizers for Pickering emulsions in such catalytic systems. Herein, we report the incorporation of PdNi alloy nanoparticles into MIL-101, where the Lewis acidity of the MOF combined with the catalytic activity of PdNi NPs enables two-step one-pot reactions. Interestingly, the resulting bimetallic PdNi@MIL-101 not only acts as an effective emulsifier to stabilize Pickering emulsions, but also exhibits superior performance in the reductive amination of Nitroarenes compared with the corresponding monometallic@MOFs. Moreover, PdNi@MIL-101 demonstrates excellent stability, maintaining high reproducibility after five consecutive cycles. This work not only reduces the catalyst cost, but also exploits the synergistic effect of bimetallic components and interfacial catalysis, which opens up new avenues for efficient and environmentally friendly organic synthesis.