COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
·
IF 4.9
Chengmin Hou,Weimin Yan,Hanxiao Ma,Yuan Bai,Zhiting Yuan
Heavy metal ion (Cu(II)) wastewater will do great harm to human body and environment, and the adsorption materials used in traditional adsorption methods are easy to hydrolyze, resulting in secondary pollution to water. In this paper, an adsorption material poly(glycidyl methacrylate-random-hydroxyethyl methacrylate) grafted ferric oxide@starch (St/Fe 3 O 4 - g -p(GMA- r -HEMA)) was prepared, which had epoxy and hydroxyl group , easy to produce crosslinking, reduce the sensitivity of starch to pH and prevent hydrolysis. Infrared spectroscopy (FTIR), thermogravimetric analysis (TG), scanning electron microscopy (SEM) and magnetometer (VSM) were used to characterize the structure and morphology of the adsorbent. The adsorption properties of the adsorbent for removal of Cu(II) ions were studied via changing the experimental conditions, including the amount of adsorbent, Cu(II) ions solution concentration, pH value, adsorption time, adsorption temperature and so on. Under the optimal adsorption conditions of pH value 7, initial Cu(II) concentration 20 mg/L and adsorption time 160 min, the maximum unit adsorption capacity of St/Fe 3 O 4 - g -p(GMA- r -HEMA) was 94.15 mg/g, and the adsorption performance was good. The adsorption process followed Langmuirm model and second-order kinetic model , and was dominated by chemisorption . The thermodynamic model showed that the adsorption process of St/Fe 3 O 4 - g -p(GMA- r -HEMA) was endothermic. After 8 adsorption cycles, 93.5% of the first adsorption effect can still be retained, and the renewable performance had been improved.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
·
2022
·
IF 3.571
Haizhu Shi,Mengzhao Wen,Xuhui Lin,Lingqiang Zhou,Lianhai Shan,Chungu Zhang,Shun Feng
Recently, metal mediated molecularly imprinted polymers (MMIPs) raise extensive attention due to their special adsorption/desorption mechanism. And the metal ion plays a key role both for MMIPs preparation and molecular recognition . But it is still a big question to select one suitable metal ion. To overcome above problem, one computational approach was proposed by calculating interaction energy (ΔE) of ternary complexes (monomer-M 2+ -template) with GAMESS software at the PBE0 level. Finally Cu(II) was screened from four doubly charged metal ions with different radii. Then Cu mediated MIP was prepared via surface imprinting technique with Fe 3 O 4 as the core in a water system. Subsequently, the adsorption behavior of the MMIP immobilized Cu(II) was investigated in detail. The results indicated the microspheres own excellent specificity and selectivity towards tetracycline (TC), as well as long-term stability and good reproducibility. The apparent maximum binding capacity and the imprinting factor were as high as 163.5 mg g − 1 and 19, respectively. Coupled with HPLC-PDA, the microspheres was successfully used as a dispersed solid phase extraction material to extract trace TC in chicken liver. At three spiking levels, mean recoveries ranged from 89.3% to 97.1% with relative standard deviations less than 4.0% (n = 3). Limits of detection and quantitation were 0.0073 mg kg − 1 and 0.024 mg kg − 1 , respectively, which can meet the strict requirement of the regulations stipulated by EU. Moreover, preliminary studies showed the radius of the metal ion and ΔE of the complexes all affect the adsorption capacity, specificity and mass transfer rate of the MMIP.
研究领域:
化学
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材料科学
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环境科学
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DOI
PubMed
高影响因子
Catalysts
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2022
·Vol. 12
·期 10
·1147
·
IF 4.501
Haowen Dai,Tian Ye,Kewei Wang,Meng Zhang,Li-Ming Wu,Gangfeng Ouyang
Bioethanol to butadiene is currently the most promising non-oil-based butadiene production route. Here, copper is introduced into the conventional bimetallic zeolite catalyst to partially substitute for zinc; the isolated tetracoordinated Cu(II) species are formed, with weak and strong basic sites transformed into medium acid sites in trimetallic CuZnY/SiBEA catalyst. A partial substitution of zinc by copper increases the dispersion of metal, reduces the formation of ZnO clusters, decreases the pore blockage, and enhances the total pore volume of catalyst. The Cu1Zn2Y5/SiBEA catalyst with an appropriate 0.33 Cu/(Cu + Zn) mass ratio, a highest medium acid sites/(weak + strong) basic sites value of 6.17, and largest total pore volume of 0.251 cm3/g in all samples presents excellent catalytic performance in the ethanol to butadiene reaction: 99.01% ethanol conversion and 73.36% butadiene selectivity, higher than most reported ethanol to butadiene catalysts. The isolated tetracoordinated Cu(II) structure is stable, which is beneficial to the stability of trimetallic catalyst; when the reaction time is 60 h, the butadiene selectivity is 45.95%, 14% higher than corresponding bimetallic catalyst. The butadiene productivity of Cu1Zn2Y5/SiBEA catalyst reaches up to 1.68 gBD·gcat−1·h−1at WHSV = 6 h−1and time-on-stream = 8 h. Increasing reaction temperature could linearly increase the ethanol conversion, while the butadiene selectivity increases first and then decreases, the suitable temperature is 375 ℃ for the highest butadiene yield.Keywords:ethanol;butadiene;CuZnY/SiBEA catalyst;acid/base ratio;isolated tetracoordinated Cu(II) structure
研究领域:
催化
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化学工程
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材料科学
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Yuhang Zhang,Donglei Li,Liang She,Furong Guo,Falong Jia,Lizhi Zhang,Zhihui Ai,Xiao Liu
Heavy metal complexes in industrial wastewater are challenging to be removed by conventional methods arising from their stable chelating structure. In this study, zero-valent iron (ZVI) was ball-milled with tiny formic acid (FA), and the as-prepared sample (FA-ZVI bm ) was attempted to eliminate a model heavy metal complex of Cu(II)-ethylenediaminetetraacetic acid (Cu(II)-EDTA). The addition of FA to ball-milling could dramatically enhance the performance of ball-milled ZVI (ZVI bm ) towards Cu(II)-EDTA removal and increase the removal rate constant by 80 times. This conspicuous improvement of Cu(II)-EDTA elimination was attributed to the ferrous formate (Fe(HCOO) 2 ) shell formed on the surface of FA-ZVI bm . Results revealed that the Fe(HCOO) 2 shell facilitated the activation of O 2 to reactive oxygen species (ROS) and the leaching of Fe 3+ . Cu(II)-EDTA was decomplexed through both oxidative destruction and Fe 3+ replacement, and the released Cu 2+ was reduced by FA-ZVI bm and immobilized synchronously. Meanwhile, the ligands underwent oxidative degradation by ROS, thus avoiding the re-chelation ecological risk. Impressively, FA-ZVI bm could achieve cyclic treatment of actual copper complex wastewater and possessed promising advantage in treatment cost. This study would offer a promising approach for eliminating Cu(II)-EDTA through EDTA ligands degradation and synchronous Cu(II) removal, moreover to shed light on the decomplexation mechanism.
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DOI
PubMed
高影响因子
Journal of Industrial Textiles
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2017
·
IF 1.75
Quan Feng,Xin Li,Dingsheng Wu,Suo Liu,Mao Ye,Shan Huan
AOPAN nanofibers were prepared by electrospinning and amidoxime modification, subsequently, HEMA was used as the monomers for surface grafting via atom transfer radical polymerization, followed by coordination with Cu(II) ions, thereafter, the nanofibers AOPAN-poly(HEMA)-Cu(II) were explored as the novel support for laccase immobilization. Scanning electron microscopy was used to visualize the morphology of the nanofibers, and Fourier transform infrared spectroscopy was used to provide information on the surface chemistry of nanofibers. At the same time, the optimization of immobilization conditions and the relative properties of the immobilized laccase were also studied in this paper. The study showed the largest amount of immobilized laccase while the reaction time of atom transfer radical polymerization was 4 h. The immobilized laccase showed a better stability resistance to temperature and pH change, and the initial activity of immobilized laccase retained (60.3 ± 3.1)%, that of the free laccase retained only (21.3 ± 2.1)% when stored at 4℃ for 24 days. Immobilized laccase maintained its initial activity after 10 repeated batches of 64.5%.
研究领域:
生物材料学
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酶工程
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高分子化学
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DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2018
·
IF 2.011
Yi-Chun Chu,Tian-Tian Wang,Xiang-Yu Ge,Peng-Hao Yang,Wei Li,Jing Zhao,Hai-Liang Zhu
Two Cu(II) complexes of the non-steroidal anti-inflammatory drug Naproxen were synthesized, characterized and evaluated for anti-inflammatory, analgesic, ulcerogenic and urease inhibition activities. The complex 1 [Cu(nap) 2 (H 2 O) 3 ]·H 2 O was reported previously, and the crystal structure of complex 2 [Cu(nap) 2 (dap)(H 2 O)] (nap = Naproxen, dap = 1,3-diaminopropane) was confirmed by X-ray diffraction crystallography . The anti-inflammatory and ulcerogenic study showed that the compounds 1 and 2 were the promising anti-inflammatory agents and demonstrated significant gastric tolerance when compared with Naproxen, especially for complex 1 with the edema inhibition of 93.6% after 3 h, and ulcer index of 15 ± 2. Analgesic and urease inhibition assay showed that complex 2 was a potent urease inhibitor with the IC 50 value of 1.69 ± 0.08 μ M and pain inhibition value of 65%. As effective urease inhibitors, molecular docking study was performed to investigate the binding mode of the complexes with urease.
研究领域:
药物化学
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生物无机化学
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药理学
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DOI
高影响因子
JOURNAL OF PHYSICAL CHEMISTRY B
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2014
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IF 3.377
Wei Li,Xiongfei Chen,Yan Fu,Jinli Zhang,Wei Li
The specific interactions of Cu2+ with self-complementary DNA sequences involving d[G4C4(GC)2G4C4], d[(GC)10], and d[(AT)10], as well as the chiral recognition mechanism of ofloxacin enantiomers via the CuII-modulated DNAs, were investigated using characterizations of circular dichroism, gel electrophoresis, FT-IR spectroscopy, UV melting measurement, electron paramagnetic resonance, and HPLC. The CuII-coordinated GC-rich DNAs exhibit amplified enantioselectivity toward the S-enantiomer of ofloxacin. Especially in the case of d[G4C4(GC)2G4C4], ofloxacin enantiomers intercalate into the two adjacent guanine bases through the minor groove mediated by Cu2+, which leads to a more favorable binding between S-ofloxacin and DNA. The highest ee value of ofloxacin enantiomers in the permeate after being adsorbed by the CuII–DNA complex is obtained as 49.2% in the R-enantiomer at the [Cu2+]/[base] molar ratio of 0.25, while at the [Cu2+]/[base] molar ratio of 0.05 the highest ee value of ofloxacin enantiomers in the retentate reaches 26.3% in the S-enantiomer. This work illustrates a novel promising route to construct DNA-based chiral selectors toward certain drug enantiomers through the programmable enantioselective recognition on the basis of DNA chirality and the specific binding of transition metal ions.
研究领域:
化学
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生物化学
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药学
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分析化学
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DOI
PubMed
高影响因子
FREE RADICAL BIOLOGY AND MEDICINE
·
2024
·
IF 7.1
Ya-Long Zheng,Yuan Ji,Yan Li,Shuai Yan,Xiao-Rong Ren,Wei Tang,Fang Dai,Bo Zhou
The development of Cu(II) ionophores for targeted disruption of aberrant redox homeostasis in cancer cells has been considered an appealing strategy in the field of anticancer research. This study presents the first identification of tanshinone I ( Ts1 ), a natural o -quinone, as a Cu(II) ionophore. Structure-activity relationship studies on tanshinones and mechanistic investigations reveal that the presence of Cu(II) effectively promotes the tautomerization of Ts1 from its diketo to keto-enol forms, thereby facilitating its sequential proton-loss Cu(II) chelation, and enabling it to function as a Cu(II) ionophore due to its structural features including the presence of an o -quinone moiety, a benzyl hydrogen, and a large conjugated system. The unique property allows Ts1 to preferentially induce copper accumulation in human hepatoma HepG2 cells over human umbilical vein endothelial cells, by releasing copper driven by reduced glutathione (GSH). This copper accumulation leads to a reduction in the GSH-to-oxidized glutathione ratio and the generation of reactive oxygen species, ultimately triggering apoptosis of HepG2 cells. The findings not only provide support for o -quinones as innovative types of anticancer Cu(II) ionophores, but also shed light on the previously unrecognized role of Ts1 as a potent Cu(II) ionophore for eradicating cancer cells by selectively disrupting their redox regulation programs, resembling a "Trojan horse".
研究领域:
肿瘤学
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药理学
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化学生物学
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Shuwei Liu,Lu Wang,Min Lin,Dandan Wang,Ziqi Song,Shuyao Li,Rui Ge,Xue Zhang,Yi Liu,Zhimin Li,Hongchen Sun,Bai Yang,Hao Zhang
Gold nanorods (AuNRs) are potentially useful in tumor theranostics, but the poor stability, high toxicity, and rapid removal by the immune system seriously limit their theranostic applications. In our study, we demonstrate the fabrication of Cu(II)-doped polydopamine-coated AuNR (AuNR@CuPDA), which significantly improves the potentials in tumor theranostics. Besides the improvement of physiological stability and biocompatibility, the PDA shell increases the photothermal performance and prolongs the blood circulation time of AuNRs. The half-life of AuNRs during blood circulation increases from 0.7 to 4.5 h after PDA coating, and the injected dose per gram of tumor tissue is 4.6% ID g–1 for AuNR@CuPDA. In addition to computer tomography imaging, the loading of Cu(II) in PDA shell endows AuNR@CuPDA with magnetic resonance imaging function. Cu(II) doped in PDA shell also exhibits chemotherapeutic behavior, and the tumor inhibitor rate is 31.2%. Further combining 808 nm laser-driven photothermal therapy, tumors were completely ablated, and no recurrence was observed. Liver and renal functions tests and histological analysis of major organs confirm that AuNR@CuPDA is in good safety.
研究领域:
纳米技术
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生物医学工程
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癌症治疗
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材料科学
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产品关联
DOI
PubMed
高影响因子
TRANSITION METAL CHEMISTRY
·
2020
·Vol. 45
·期 7
·493-500
·
IF 1.366
Yang Xinda,Gu Shunxin,Jiang Qin,Wang Yanqing,Wang Daqi,Shi Pengfei
Abstract A Cu(II) complex [Cu 2 (phen) 2 (NAB) 2 (HO)] n (phen = 1, 10-phenanthroline and NABH = p -N, N-(2-hydroxyethyl)amino benzoic acid) was synthesized, and its structure was confirmed by X-ray diffraction. The structure of the complex appeared to be clamp-like, in which Cu(II) atoms adopt distorted square pyramidal geometry. Each Cu(II) is coordinated by two nitrogen atoms in phen ligand and two carboxyl oxygen atoms from each of the two NABH ligands. The clamp-like coordination units are bridged by adjacent hydroxyethyl groups into infinite 1D chain, which are further linked by extensive O···H hydrogen bonds and π–π interactions to form 3D networks. The titled complex displayed weak double-stranded DNA interaction activity. Spectroscopic and theoretical simulation results indicated that the complex attached onto DNA surface through hydrogen bonding with base pairs. Graphic abstract A novel benzoic acid derivative with two extremity hydroxyethyl groups was designed and used as auxiliary ligand to synthesize mixed coordinating clamp-like Cu(II)-phenanthroline complex. Hydrogen bonding played crucial role in bridging the clamps into infinite 1D chain and also the DNA complex interaction mode.
研究领域:
无机化学
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生物化学
·
分子生物学
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产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 27
·期 1
·812-822
·
IF 2.914
Xu Suyun,Yan Ning,Cui Minghao,Liu Hongbo
In this study, ozone-oxidation was used to treat synthetic chemical plating solution containing Cu(II)/Ni(II)-EDTA solution to realize the purpose of decomplexation. The effects of solution pH, initial concentration of Cu(II)/Ni(II)-EDTA, the molar ratio of EDTA to Cu(II)/Ni(II), and the coexistence of Cu(II)/Ni(II) on their removal efficiencies were investigated. The degradation of EDTA-Cu(II) and EDTA-Ni(II) were mainly attributed to OH oxidation, and the removal rates of Cu(II)/Ni(II) depend on the complete decomplexation. The removal rates of Cu(II) and Ni(II) was affected by the pH of solution, and the optimal pH was found to be 7–9; nevertheless, their removal rates can still be up to 90% even in acidic pHs of 3~5. When the molar ratio of EDTA to Cu(II)/Ni(II) increased from 1:1 to 3:1, the kinetics of metal ion removal rate declined from 0.0788 and 0.1139 min -1 to 0.0250 and 0.0271 min -1 . The synergistic effect was found in the Cu(II)/Ni(II) blended system due to the higher catalytic capability and the lower complexation affinity toward EDTA for Ni(II). In summary, ozone oxidation can be considered as an effective technology to realize the complete decomplexation of Cu(II)/Ni(II)-EDTA that contained in chemical plating industry wastewater.
Graphical Abstract
研究领域:
环境科学
·
化学工程
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DOI
高影响因子
Scientific Reports
·
2025
·Vol. 15
·期 1
·1-11
·
IF 3.9
Wahid Ehtisham,Ocheja Ohiemi Benjamin,Oguntomi Sunday Olakunle,Pan Run,Grattieri Matteo,Guaragnella Nicoletta,Guaragnella Cataldo,Marsili Enrico
Electrodes functionalised with weak electroactive microorganisms offer a viable alternative to conventional chemical sensors for detecting priority pollutants in bioremediation processes. Biofilm-based biosensors have been proposed for this purpose. However, biofilm formation and maturation require 24–48 h, and the microstructure and coverage of the electrode surface cannot be controlled, leading to poorly reproducible signal and sensitivity. Alternatively, semiconductive biocompatible coatings can be used for viable cell immobilization, achieving reproducible coverage and resulting in a stable biosensor response. In this work, we use a polydopamine (PDA)-based coating to immobilize Saccharomyces cerevisiae yeast viable cells on carbon screen printed electrodes (SPE) for Cu(II) detection, with potassium ferricyanide (K 3 [Fe (CN) 6 ]) as a redox mediator. Under these conditions, the current output correlates with Cu (II) concentration, reaching a limit of detection of 2.2 µM, as calculated from the chronoamperometric response. The bioelectrochemical results are supported by standard viability assays, microscopy, and electrochemical impedance spectroscopy. The PDA coatings can be functionalised with different mutant strains, thus expanding the toolbox for biosensor design in bioremediation.
研究领域:
微生物学
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环境科学
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生物技术
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）