MICROCHIMICA ACTA
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2020
·Vol. 187
·期 6
·1-9
·
IF 6.232
Wang Xianfeng,Yang Yixia,Huo Danqun,Ji Zhong,Ma Yi,Yang Mei,Luo Huibo,Luo Xiaogang,Hou Changjun,Lv Jiayi
N-Doped silicon quantum dots (N-SiQD) were synthesized using N-[3-(trimethoxysily)propyl]-ethylenediamine and citric acid as silicon source and reduction agent, respectively. The N-SiQD shows a strong blue fluorescence with a high quantum yield of about 53%. It is found that a selective static quenching process occurs between N-SiQDs and Cu 2+ . Glyphosate can inhibit this phenomenon and trigger the rapid fluorescence enhancement of the quenched N-SiQDs/Cu 2+ system due to the specific interaction between Cu 2+ and glyphosate. With such a design, a turn-on fluorescent nanoprobe based on N-SiQD/Cu 2+ system was established for rapid determination of glyphosate. The determination signal of N-SiQD/Cu 2+ was measured at the optimum emission wavelength of 460 nm after excitation at 360 nm. Under optimal conditions, the turn-on nanoprobe showed a linear relationship between fluorescent response and glyphosate concentrations in the range 0.1 to 1 μg mL −1 . The limit of determination was calculated to 7.8 ng mL −1 (3σ/S). Satisfactory recoveries were obtained in the determination of spiked water samples, indicating the potential use for environmental monitoring.
Schematic representation of N-SiQD/Cu 2+ system for glyphosate determination. Fluorescence quenching of N-SiQDs induced by copper ions and the succedent fluorescent “turn on” triggered by glyphosate
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CHINESE JOURNAL OF POLYMER SCIENCE
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2020
·Vol. 38
·期 8
·867-876
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IF 3.154
Chen Qi,Wang Shun,Qin Feng,Liu Kuan,Liu Qian,Zhao Qing,Wang Xing-Yi,Hu Yan-Hong
Polyimide (PI) synthesized from aromatic diamine and dianhydrides via two-step poly-condensation method was highly soluble in TGDDM (MY-720) and DGEBA (E-51) at desirable temperature. TGDDM-PI (M-PI) and DGEBA-PI (E-PI) composites within 0.5%-3% PI loading could be prepared without organic solvent. On the cryogenically fractured surfaces of M-PI and E-PI composites, no obvious heterogeneous phase was observed by SEM. The mechanical properties were promoted significantly by PI, especially for impact strength. Adding 2% PI-2W into MY-720 and E-51 composites, the impact strength increased to 21 and 51 kJ/m 2 , the tensile strength increased by 62% and 19%, and the flexural strength by 18% and 13%, respectively, with slight increases in tensile modulus. These results were related to the promotion in plasticity of composites and changes in fragile→ductile fracture mode. Moreover, T g and thermal stability of M-PI and E-PI were increased effectively.
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Nano Convergence
·
2020
·Vol. 7
·期 1
·1-18
·
IF 2.919
Cao Dingding,Shu Xugang,Zhu Dandan,Liang Shengli,Hasan Murtaza,Gong Sheng
ZnO nanoparticles are widely used in biological, chemical, and medical fields, but their toxicity impedes their wide application. In this study, pristine ZnO NPs (~ 7 nm; ~ 18 nm; ~ 49 nm) and lipid-coated ZnO NPs (~ 13 nm; ~ 22 nm; ~ 52 nm) with different morphologies were prepared by chemical method and characterized by TEM, XRD, HRTEM, FTIR, and DLS. Our results showed that the lipid-coated ZnO NPs (~ 13 nm; ~ 22 nm; ~ 52 nm) groups improved the colloidal stability, prevented the aggregation and dissolution of nanocrystal particles in the solution, inhibited the dissolution of ZnO NPs into Zn2+ cations, and reduced cytotoxicity more efficiently than the pristine ZnO NPs (~ 7 nm; ~ 18 nm; ~ 49 nm). Compared to the lipid-coated ZnO NPs, pristine ZnO NPs (~ 7 nm; ~ 18 nm; ~ 49 nm) could dose-dependently destroy the cells at low concentrations. At the same concentration, ZnO NPs (~ 7 nm) exhibited the highest cytotoxicity. These results could provide a basis for the toxicological study of the nanoparticles and direct future investigations for preventing strong aggregation, reducing the toxic effects of lipid-bilayer and promoting the uptake of nanoparticles by HeLa cells efficiently.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 27
·期 19
·24013-24024
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IF 3.056
Zhang Zhaoxue,Zhang Nan,Li Haipu,Lu Yi,Yang Zhaoguang
The contents of total arsenic (tAs), inorganic arsenic (iAs), Cd, Cr, Cu, Mn, Ni, Pb, Sb, and Zn in 135 rice grain samples from Zijiang River basin were determined, and the probabilistic distribution of noncarcinogenic and carcinogenic risks associated with ingesting locally produced rice was determined by Monte Carlo simulation. Further, multivariate statistical analysis was used to analyze the potential sources of the heavy metals in rice grains. The average concentrations of the heavy metals in rice grains were ranked as follows: Mn (17.314 mg/kg) > Zn (16.043 mg/kg) > Cu (2.013 mg/kg) > Ni (1.332 mg/kg) > Cr (0.571 mg/kg) > Cd (0.283 mg/kg) > tAs (0.241 mg/kg) > Pb (0.145 mg/kg) > Sb (0.027 mg/kg). These heavy metals were significantly enriched in some rice grain samples. The analysis of potential sources indicated that As, Pb, Sb, and Zn were mainly derived from mining and smelting and agricultural activities; Cd, Cu, Mn, and Ni were mainly derived from the agricultural activities; Cr were mainly derived from the natural source. The results of Monte Carlo simulation indicated that ingestion of rice grown in the area may pose health risks for children, adult males, and adult females. The noncarcinogenic risks were mainly from As, Cd, Mn, Ni, and Sb, and the carcinogenic risk was mainly from As, Cd, and Ni. This study could provide basic information for land management and rice intake in the study area.
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Cancer Cell International
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2020
·Vol. 20
·期 1
·1-14
·
IF 4.175
Yuan Yin,Li Bo,Kuang Yanbin,Ni Shuo,Zhuge Aoxiang,Yang Jing,Lv Longxian,Gu Silan,Yan Ren,Li Yating,Wang Kaicen,Yang Liya,Zhu Xueling,Wu Jingjing,Bian Xiaoyuan,Li Lanjuan
Background Dietary fiber is effective for colorectal cancer (CRC) treatment. Interleukin-6 (IL-6) and its adaptors are potential targets for CRC therapy. Butyrate, a metabolite of dietary fiber, is a new, highly safe type of targeted drug. Methods In this study, Cell Counting Kit-8 cell viability and wound healing assays, western blot analysis, immunofluorescence staining, and xenograft tumor mouse models were used to evaluate the anticancer effect of butyrate and its possible mechanism in vivo and in vitro. Results Dietary fiber and sodium butyrate (NaB) decreased CRC burden by decreasing IL-6 receptor gp130 and blocking IL-6/JAK2/STAT3 axis activation in vitro and in vivo. Furthermore, NaB reduced the gp130 protein level by regulating its degradation rate via targeting TRAF5. Conclusions The fiber metabolite butyrate inhibits CRC development by reducing gp130 via TRAF5.
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NPG Asia Materials
·
2020
·Vol. 12
·期 1
·1-11
·
IF 8.131
Yuan Zihan,Guo Xiaoshuang,Wei Minyan,Xu Yang,Fang Zhiwei,Feng Yun,Yuan Wei-En
Small-interfering RNA (siRNA) can specifically silence disease gene expression, bringing hope for the effective treatment of gene-related diseases. However, its use in vivo is limited due to the lack of efficient carriers. Therefore, it is necessary to construct carriers with high efficiency, low toxicity and serum stability. As a promising polycation carrier, polyethylenimine (PEI) can be further modified with a fluorine-containing alkyl chain that brings hydrophobic and oleophobic characteristics to its surface. In this study, low molecular weight PEI 1.8 kDa was selected and fluorinated through an anhydride reaction, and the product was named PEIF. In vitro experiments have shown that PEIF/siRNA polyplexes have suitable and stable particle size and potential, compress nucleic acids at a very low w / w ratio, and have the ability to effectively silence specific genes with low cytotoxicity. Compared with the polyplexes prepared using PEI 25 kDa, the PEIF/siRNA polyplexes were more stable in serum, showed a better antiangiogenic ability in in vivo experiments, and had a better tumor inhibition effect. The above results indicate that fluoropolymers based on the fluorine effect have great potential as gene delivery carriers for tumor therapy.
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CELLULOSE
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2020
·Vol. 27
·期 9
·5169-5178
·
IF 4.21
Yang Jin,Xie Atian,Cui Jiuyun,Chen Yangyang,Lang Jihui,Li Chunxiang,Yan Yongsheng,Dai Jiangdong
With the increase of oil spills, leakage of chemical products and discharge of oily wastewater, oil–water separation has become an urgent problem. In this study, polydopamine (PDA) was first coated on the surface of paper fibers (PF@PDA) by CuSO 4 /H 2 O 2 triggering to accelerate the reaction rate. Then, the BaSO 4 nanosheets were deposited on the surface of PF@PDA membrane by alternating soaking process (ASP) to obtain superhydrophilic/underwater superoleophobic membrane (PF@PDA/BaSO 4 ) for oil/water separation. PF@PDA/BaSO 4 shows good separation efficiency (more than 99%) and high flux (more than 550 L m −2 h −1 ) for various oil–water mixtures. Importantly, the membrane shows excellent acid, alkali and salt resistance that maintains the high separation performance even under acid, base and salt solution environments. Moreover, the PF@PDA/BaSO 4 membrane has excellent antifouling property and outstanding reusability. Our PF@PDA/BaSO 4 with low cost, easy preparation and high performance has a good application prospect for oil/water separation even in harsh environments.
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ACTA PHARMACOLOGICA SINICA
·
2020
·Vol. 41
·期 9
·1208-1222
·
IF 5.064
Almoiliqy Marwan,Wen Jin,Xu Bin,Sun Yu-chao,Lian Meng-qiao,Li Yan-li,Qaed Eskandar,Al-Azab Mahmoud,Chen Da-peng,Shopit Abdullah,Wang Li,Sun Peng-yuan,Lin Yuan
Our preliminary study shows that cinnamaldehyde (CA) could protect against intestinal ischemia/reperfusion (I/R) injuries, in which p53 and NF-κB p65 play a synergistic role. In this study, we conducted in vivo and in vitro experiments to verify this proposal. SD rats were pretreated with CA (10 or 40 mg · kg −1 · d −1 , ig) for 3 days, then subjected to 1 h mesenteric ischemia followed by 2 h reperfusion. CA pretreatment dose-dependently ameliorated morphological damage and reduced inflammation evidenced by decreased TNF-α, IL-1β, and IL-6 levels and MPO activity in I/R-treated intestinal tissues. CA pretreatment also attenuated oxidative stress through restoring SOD, GSH, LDH, and MDA levels in I/R-treated intestinal tissues. Furthermore, CA pretreatment significantly reduced the expression of inflammation/apoptosis-related NF-κB p65, IKKβ, IK-α, and NF-κB p50, and downregulated apoptotic protein expression including p53, Bax, caspase-9 and caspase-3, and restoring Bcl-2, in I/R-treated intestinal tissues. We pretreated IEC-6 cells in vitro with CA for 24 h, followed by 4 h hypoxia and 3 h reoxygenation (H/R) incubation. Pretreatment with CA (3.125, 6.25, and 12.5 μmol · L −1 ) significantly reversed H/R-induced reduction of IEC-6 cell viability. CA pretreatment significantly suppressed oxidative stress, NF-κB activation and apoptosis in H/R-treated IEC-6 cells. Moreover, CA pretreatment significantly reversed mitochondrial dysfunction in H/R-treated IEC-6 cells. CA pretreatment inhibited the nuclear translocation of p53 and NF-κB p65 in H/R-treated IEC-6 cells. Double knockdown or overexpression of p53 and NF-κB p65 caused a synergistic reduction or elevation of p53 compared with knockdown or overexpression of p53 or NF-κB p65 alone. In H/R-treated IEC-6 cells with double knockdown or overexpression of NF-κB p65 and p53, CA pretreatment caused neither further decrease nor increase of NF-κB p65 or p53 expression, suggesting that CA-induced synergistic inhibition on both NF-κB and p53 played a key role in ameliorating intestinal I/R injuries. Finally, we used immunoprecipitation assay to demonstrate an interaction between p53 and NF-κB p65, showing the basis for CA-induced synergistic inhibition. Our results provide valuable information for further studies.
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JOURNAL OF THERMAL SPRAY TECHNOLOGY
·
2020
·Vol. 29
·期 5
·1172-1182
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IF 2.522
Zhai Mengjiao,Liu Yi,Huang Jing,Hou Wenjia,Wu Songze,Zhang Botao,Li Hua
Abstract A novel TiO 2 -SrCO 3 co-catalyst with a porous structure was fabricated by suspension plasma spraying. SrTiO 3 as revealed by high-resolution TEM was formed by the chemical reaction of TiO 2 with SrCO 3 during the high-temperature plasma spraying. A narrow band gap (2.58 eV) and reduction in the recombination speed of photoinduced carriers of the coatings were detected by UV–visible diffuse reflectance spectrometry and fluorescence spectrometry, respectively. The enhanced visible light-driven photodegradation properties of the coatings resulted in promoted degradation of methylene blue. The composite coatings also demonstrated significantly pronounced bactericidal activities against the Gram-negative bacterium Escherichia coli than the pure TiO 2 coatings, achieving a killing rate of over 99.7%. The results give insights on the potential to fabricate large-scale nano-TiO 2 -based porous photocatalytic coatings by suspension plasma spraying for versatile environmental applications. Graphic Abstract
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2020
·Vol. 31
·期 9
·6698-6705
·
IF 2.22
Xu Mingyuan,Yan Luting,Zhu Yanyun,Li Yuting,Song Xiaodong,Yin Lan
Polydopamine (PDA)-coated gold nanoparticles (Au@PDA) were used as electronic transport layer (ETL) modifiers in PTB7:PC71BM polymer solar cells. PDA can effectively modify the surface of gold nanoparticles (Au NPs) and improve the stability of them. In addition, PDA also effectively binds to ZnO ETL, reducing surface defect and improving the combination between the interface layer and the active layer. In this study, AuNPs with particle size of about 30 nm was prepared by Frens reduction method, and then the dopamine (DA) self-polymerized on the surface of them to obtain a core–shell structural material Au@PDA. By regulating the polymerization time of DA, different PDA shell thickness was obtained. The Au@PDA was introduced into ZnO ETL to generate local plasmon resonance adsorption. When dopamine polymerized for an hour, the short current density of the modified solar cells reached 13.98 mA/cm 2 , and the power conversion efficiency reached 6.03%, which was 130% of the device without Au@PDA.
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JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 26
·11856-11869
·
IF 3.553
Lu Yan,Chang Zhaosen,Zhang Shizhen,Wang Shunli,Chen Qi,Feng Lijuan,Sui Zhuyin
Abstract Cycloaddition reaction using CO 2 as a starting material to form a cyclic carbonate has been applied to chemical fixation of CO 2 . In order to further increase the reaction efficiency, herein, a bifunctional catalyst ( CPBrs ) containing metalloporphyrin and quaternary phosphonium salt groups was prepared, and the related catalytic performance for CO 2 conversion was also studied. The catalytic system possesses multiple active sites of zinc porphyrin (Lewis acids) and quaternary phosphonium bromide salts (nucleophilic reagents), which can cooperatively work together to enhance the efficiency of cycloaddition reaction. At the same time, CPBrs ( CPBr-1 and CPBr-2 ) are microporous polymers with permanent microporous pore structure and high specific surface areas (342–370 m 2 g −1 ). Their moderate capacities (5.76 and 8.81% at 1 bar/273 K) to capture carbon dioxide were also beneficial for CO 2 conversion. The activity of the bifunctional catalyst is higher than that of the catalyst with a single component. The corresponding highest yield to catalyze cycloaddition reaction between methyl substituented propylene oxide and CO 2 is up to 95% (2.5 MPa, 90 °C). What is more, the porous nature of catalysts provides the recoverability of the catalyst, and the efficiency of the catalyst CPBr-2 remains high (above 90% yield) after five catalytic recycle. Graphic abstract
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JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 24
·10942-10952
·
IF 3.553
Fan Chunying,Luo Yan
Plastic wastes have posed serious environmental and health issues. Recycling plastic wastes to produce value-added products, however, still remains challenging. Herein, porous nanocomposites derived from polyethylene film wastes were fabricated via thermally induced phase separation method, in which they were employed as supported substrates to self-assemble functional components into multifunctional materials with unique property profiles. The resulting polymeric porous nanocomposites consisting of hybrid nanoparticles and flexible polyethylene bulk not only provided excellent UV resistance, but also ensured superior mechanical robustness against external decomposition and injuries. Specific properties and functionalities, including the sequential combination of functional ink and superhydrophobic layer, were successfully incorporated into the porous nanocomposites by altering functional components. The self-assembly properties of these final multifunctional materials were demonstrated by different performance tests, such as indicating temperature, conductive electrode, superhydrophobic layer. It is found that our fabrication methodology holds great potential for efficient recovery of polyethylene film wastes toward advancing sustainability goals. Furthermore, the proposed self-assembly strategy provides a promising route to develop multifunctional materials with tunable functions and high performance for future designing of smart materials.
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危险品化学品经营许可证（带存储）