Frontiers in Bioengineering and Biotechnology
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2024
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IF 4.3
Ruijie Wang,Ning Zhou,Jinfang Xue,Yan Li,Yang Wang,Huadong Zhu,Chuanzhu Lv
Background: In sepsis, the lung is one of the worst affected organs, often leading to acute lung injury (ALI). More and more evidence suggests that macrophages are also involved in the pathogenesis of ALI. In our previous study, we successfully synthesized Iron-capsaicin-based nanoparticles (Fe-CAP NPs) and found that it could inhibit the secretion of inflammatory cytokines to alleviate ALI. Here, we further explore the anti-inflammatory mechanism of Fe-CAP NPs.Methods: Bone marrow-derived macrophages (BMDM) and C57 mice were divided into four groups: control group, lipopolysaccharide (LPS) group, CAP + LPS group and Fe-CAP + LPS group. Western blot and Immunofluorescence were used to detect the expression of macrophage phenotypic markers CD86 and CD206 in BMDM and lung tissue. Fluorescence microbeads, Transwell and ROS kit were used to detect the phagocytosis, migration and ROS clearing capability of BMDM. Western blot was used to detect the expression of JAK2/STAT3 pathway and apoptosis proteins in BMDM. TUNEL kit and H&E staining were used to evaluate apoptosis and pathological changes in lung tissue.Results: In vitro, CD86 expression was increased in LPS, but decreased after Fe-CAP pretreatment. CD206 expression was the opposite. Fe-CAP reduced phagocytosis, migration and scavenged ROS in LPS-treated BMDM. Fe-CAP inhibited P-JAK2 and P-STAT3 expression and reduced apoptosis. In vivo, Fe-CAP improved lung histopathology and reduced apoptosis in lung tissue of LPS group. CD86 expression was increased in lung tissue of LPS group, but decreased in Fe-CAP preconditioning, and CD206 expression was reversed.Conclusion: Fe-CAP NPs could alleviate sepsis-induced ALI by regulating the polarization and function of macrophages, reducing ROS level and apoptosis.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yuxuan Shao,Junjie Ni,Jie Yin,Xinqing Liu,Yulai Song,Yue Xu,Shuai Guo,Laima Luo
The construction of heterojunctions between non-noble-metal based compounds affords a scheme for accelerating the reaction kinetics of oxygen evolution reaction (OER) without using precious mental materials, which is extremely important but remains challenging. Herein, the heterogeneous structure between Fe 60 Co 10 Ni 10 Cr 10 Mn 10 medium-entropy alloy (MEA) and FeS 2 is developed by a mechanical alloying approach. The resulting MEA-30 wt%FeS 2 delivers a high OER activity with a low overpotential of 261.6 mV at 10 mA/cm 2 , along with Tafel slope of 52.7 mV/dec in 1.0 mol/L KOH solution, superior to the commercial RuO 2 . The combination of detailed characterization techniques and density functional theory (DFT) calculation reveals that the heterojunctions between Fe-based MEA and FeS 2 generates the synergistic effect on the activation and formation steps of OOH*, thus promoting the OER reaction kinetics. Furthermore, the abundant active sites provided by the reconstructions of MEA-30 wt%FeS 2 during OER process also contributes to the catalytic performance. This work greatly expands the application scope of medium-entropy materials and provides a new method for the fabrication of novel heterogeneous electrocatalyst of Fe-based MEA and FeS 2 .
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SURFACE & COATINGS TECHNOLOGY
·
2024
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IF 5.3
Zhijie Jing,Peng Xu,Ling Wang,Rou Liang,Chi Pang
In this work, ultrasonic-assisted laser cladding technology was employed to fabricate shape memory alloy (SMA) coatings composed of Fe-Mn-Si-Cr-Ni on the surface of 304 stainless steel. Both experimental and simulated results unequivocally demonstrate a substantial improvement in both microhardness and wear resistance of the metal surface. Subsequently, a superhydrophobic coating with an “armor-like” structure was comprehensively prepared by integrating femtosecond laser (FSL) and nano SiO 2 spray-coating techniques. The creation of this microstructure on the coating surface efficiently facilitated the high-efficiency embedding of nano SiO 2 particles. Notably, the modified SMA coating exhibited stable superhydrophobic properties and exceptional corrosion resistance. This research not only provides novel approaches and methods for the preparation and modification of Fe-based memory alloy coatings but also highlights potential applications in the corrosion-resistant field. The work offers valuable insights for researchers in the field of materials science, emphasizing the synergistic effects of ultrasound-assisted laser cladding technology, femtosecond laser, and nano SiO 2 spraying techniques. It provides robust support for the development of new functional coatings.
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ChemCatChem
·
2024
·
IF 3.8
Chengzhuo Yu,Jin Xu,Yarui Wang,Silong Wang,Li Xiong,Fanglan Geng,Zesen Shang,Huasheng Wu,Jitao Lv,Lixia Zhao,Yawei Wang
Graphical Untill now, reactive oxygen species (ROS) are difficult to generate in the natural light conditions, since most photocatalysts require external strong stimuli. We surprisingly found the ROS generation on MIL-100(Fe)/TiO 2 driven by mild natural light. The ROS generation patterns and mechanism of MIL-100(Fe)/TiO 2 was revealed by chemiluminescence (CL) and density functional theory (DFT). Reactive oxygen species (ROS), as one kind of the most highly oxidizing oxidants, are difficult to generate and utilize in the natural light conditions, since many materials require external strong stimuli for ROS release to be effective as pollutant degradation or biocide. In this work, we surprisingly found the ROS generation on MIL-100(Fe)/TiO 2 driven by mild natural light. Then ROS generation patterns and mechanism was revealed by chemiluminescence (CL) and density functional theory (DFT). Meanwhile, rhodamine B (RhB) can also be removed by MIL-100(Fe)/TiO 2 under natural light, which further evidence the ROS generation under the natural light. This work provides a new direction for spontaneously generating ROS releasing without external strong stimuli and has the broad potential applications in the field of pollutant degradation or antimicrobials under natural conditions.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Xin Li,Wanrong Bu,Ke Zhu,Yuwen Chen,Xiaoying Liang,Bin Wang,Yuchen Wang,Kai Yan
Single-atom catalysts (SACs) as photo-Fenton-like catalysts have attracted widespread attention in water purification. However, the development of SACs with renewability, cleanliness, high mass loading, and raw material abundance is a formidable challenge to achieve efficient pollutant removal. In this study, we fabricated high-performance Fe-nanocluster embedded biomass-derived carbon (Fe/Bio-C) from Ficus altissima wastes for quinolone antibiotics degradation. The high-angle annular dark-field scanning transmission electron microscopy with aberration correction (AC-HAADF-STEM) and X-ray absorption fine structure spectroscopy (XAFS) revealed that the Fe/Bio-C exhibited a porous structure with abundant Fe-N 4 active sites. The Fe/Bio-C catalysts achieved an exceptional efficiency of 98.6 % for the removal of the representative quinolone antibiotic, namely lomefloxacin (LOM), within 30 min. Furthermore, an in-depth exploration was conducted to assess the influence of reaction parameters on degradation performance, kinetics, toxicity, and mechanism. The free radical quenching experiments and electron paramagnetic resonance (EPR) spectra demonstrated the existence of ·O 2 − , 1 O 2 , ·OH, SO 4 · − in the reaction system and the ·O 2 − radicals played a relatively important role in the degradation progress. This work broaden the avenue for constructing metal-nanocluster photocatalysts with the high reactivity, low metal leaching, and universality to various pollutants.
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Surfaces and Interfaces
·
2025
·
IF 6.3
Bolong Liang,Xiaoyu Huang,Xi Zhu,Hongbin He,Shu-xuan Liang
Ciprofloxacin accumulates in aqueous environment due to its non-degradability. Photocatalysis, as an economical and efficient treatment technology for organic matter, is mostly used to remove antibiotics from water environment. However, the photocatalytic performance is limited by photocatalysts, which suffer from wide band gap and severe recombination of photogenerated electrons and holes. Therefore, we developed a Z-scheme heterojunction photocatalyst Fe-ZIF-8@AgCl, which was synthesized by combining pre-prepared Fe-ZIF-8 with AgCl. Meanwhile, the X-ray diffractometer, scanning electron microscopy, transmission electron microscopy, Brunauer-Emmett-Teller analysis and X-ray photoelectron spectroscopy were employed to characterize the structure of Fe-ZIF-8@AgCl, and a series of photoelectric tests were conducted to demonstrate the photocatalytic properties of Fe-ZIF-8@AgCl. The results revealed that Fe-ZIF-8@AgCl had a remarkable 71.9 % removal efficiency of ciprofloxacin by photodegradation in 120 min. Fe-ZIF-8@AgCl could help reduce band gap energy, inhibit the recombination of photoelectrons and holes, lower the charge transfer resistance, and enhance the photocurrent response. Furthermore, Fe-ZIF-8@AgCl still maintained a high photocatalytic performance after 4 cycles, and ·O 2 - was detected and identified as the main photocatalytic active factor. Subsequently, the charge transfer mechanism of direct Z-scheme heterojunction was proposed, and the photocatalytic degradation pathways of ciprofloxacin were analyzed. In this study, Z-scheme heterojunction photocatalyst was prepared and showed great potential for efficient photodegradation of ciprofloxacin.
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Regenerative Biomaterials
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2024
·
IF 5.6
Yang Shuaikang,Wang Weiqiang,Xu Yanan,Yuan Yonghui,Hao Shengzhi
Fe-based biodegradable materials have attracted significant attention due to their exceptional mechanical properties and favorable biocompatibility. Currently, research on Fe-based materials mainly focuses on regulating the degradation rate. However, excessive release of Fe ions during material degradation will induce the generation of reactive oxygen species (ROS), leading to oxidative stress and ferroptosis. Therefore, the control of ROS release and the improvement of biocompatibility for Fe-based materials are very important. In this study, new Fe–Zn alloys were prepared by electrodeposition with the intention of using Zn as an antioxidant to reduce oxidative damage during alloy degradation. Initially, the impact of three potential degradation ions (Fe2+, Fe3+, Zn2+) from the Fe–Zn alloy on human endothelial cell (EC) activity and migration ability was investigated. Subsequently, cell adhesion, cell activity, ROS production and DNA damage were assessed at various locations surrounding the alloy. Finally, the influence of different concentrations of Zn2+ in the medium on cell viability and ROS production was evaluated. High levels of ROS exhibited evident toxic effects on ECs and promoted DNA damage. As an antioxidant, Zn2+ effectively reduced ROS production around Fe and improved the cell viability on its surface at a concentration of 0.04 mmol/l. These findings demonstrate that Fe–Zn alloy can attenuate the ROS generated from Fe degradation thereby enhancing cytocompatibility.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2024
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IF 20.2
Qiang Zhong,Yan Xue,Zihao Qi,Yue Sun,Leliang Wu,Dunyu Sun,Chenmin Xu,Kwangchol Ri,Shaogui Yang,Jiandong Zhu,Qiuyi Ji,Yazi Liu,Shiyin Li,Huan He
Two-dimensional cage-in-cage carbon-coated FeSeS superlattices with varying degrees of sulfidation (FeSeS@C) are developed for activating peroxymonosulfate (PMS) to effectively degrade diatrizoic acid (DTZ), and the intrinsic origin that govern the activity of FeSeS@C are deeply elucidated. Experimental and theoretical analyses manifested that proper sulfidation led to increased surface acidity of FeSeS@C. The high surface acidity can optimize the exposure and spin state of Fe sites for FeSeS@C-4, a high spin state of Fe (6.27 μ B ) not only regulating PMS adsorption for enhancing the charge density, but also expediting interfacial charge deliver to trigger the efficient PMS activation. Therefore, among FeSeS@C, FeSeS@C-4 exhibited the best degradation performance for DTZ, with first-order kinetic rate constants (k obs ) of 0.232 min −1 and degradation rate of 100 %. This study demonstrates a novel application of cage-in-cage superlattices in environmental remediation and offers new insights into the mechanism of PMS activation by sulfur modification Fe-based catalysts.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2024
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IF 9.4
Yuzhen Zhang,Huajun Zhou,Peihua Zhao,Kai Yuan,Rui Zhou,Yongping Qu,Yanzhong Wang
The oxygen evolution reaction (OER) is a complex four-electron transfer process that poses a significant challenge to the efficient production of hydrogen through water splitting. However, developing non-noble metal electrocatalyst with excellent OER performance is still a big challenge. Herein, we propose a new strategy for the in-situ growth of two-dimensional amorphous/crystalline thiophene-based Ni-Fe metal–organic frameworks (MOFs) using Ni-Fe foam (NFF) as metal source and current collector, and thiophene-2,5-dicarboxylic acid (TDC) as corrosion agent and ligand. TDC was ionized at high temperature to produce H + ions that etch NFF to release Ni 2+ and Fe 2+ ions, which were coordinated with TDC to in situ synthesize two-dimensional Ni-Fe thiophenedicarboxylate coordination polymer (NiFe-TDC) nanobelts on NFF. The unique structure and synergistic effect of Ni and Fe ions of NiFe-TDC 0.05 result in the excellent OER performance with an overpotential of 224 and 256 mV at current densities of 10 and 100 mA cm −2 , respectively, and it can run stably for 100 h at a current density of 100 mA cm −2 , indicating the outstanding stability. Furthermore, NiFe-TDC 0.05 remains the excellent OER performance with an extremely low potential of 196 and 271 mV at current densities of 10 and 100 mA cm −2 in seawater with 1 mol L -1 (M) KOH, respectively. The assembled NiFe-TDC 0.05 || Pt/C water electrolysis cell achieves a current density of 100 mA cm −2 at a low voltage of 1.78 V. The work provides a new method to prepare two dimensional MOFs for efficient water oxidation.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Hanmeng Yuan,Zhimin Zhao,Chenguang Wang,Hongshuai Gao,Yi Nie
With the rising prevalence of lithium-ion batteries, efficient recovery of metal ions, particularly those potentially released from LiFePO 4 anodes, has become critical. Given that both Fe 3+ and Li + ions can form electrostatic adsorptive interactions, achieving effective separation of conventional adsorbent materials becomes challenging. This study presents an amino acid-functionalized nanocellulose hydrogel (ANH) synthesized by incorporating L-threonine, which significantly enhances the selective adsorption of Fe 3+ in a mixed-ion environment by leveraging coordination differences between Li + and Fe 3+ . The morphology, functional groups, and pore structure of ANH were extensively characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, and mercury intrusion porosimetry techniques. Through batch experiments, the adsorption thermodynamics and isotherms of ANH for Fe 3+ were examined. Furthermore, the adsorption selectivity of ANH for Li + and Fe 3+ was evaluated in a mixed-ion system, revealing that the adsorption capacity for Fe 3+ was four times higher than for Li + at elevated concentrations. The adsorption mechanism of Li + /Fe 3+ was elucidated through multi-scale simulations, and the influence of varying amino acid grafting degree on adsorption metrics, such as solvent-accessible area and hydrogen bonding numbers, was investigated. The combination of experimental and theoretical results demonstrates the potential of ANH to inform the development of high-performance, selective adsorbents.
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CHEMICAL ENGINEERING SCIENCE
·
2024
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IF 4.1
Chongyang Wei,Xiaoxue Han,Shouying Huang,Haoting Liang,Yidan Wang,Ting Li,Yong Wang,Yue Wang,Xinbin Ma
In the Fischer–Tropsch synthesis (FTS) reaction, the intricate reaction conditions are prone to induce phase transitions in iron carbides, which markedly affect catalytic performance. Manipulating and stabilizing the active phase is paramount for ensuring the catalyst efficiency. In this study, we regulated the Fe-Zn interaction to investigate the influence of iron carbides and the characteristics of surface carbon species. The strong interaction significantly enhanced the adsorption and dissociation of CO on the catalyst surface, thereby facilitating the formation of carbon-rich Fe 2(.2) C. Consequently, the FeZn-s catalyst exhibited the highest iron time yield (FTY) of 959 μmol CO ·g Fe - 1 ·s - 1 . But meanwhile, the stronger Fe-Zn interaction also accelerated the carbon deposition rate and elevated the graphitization degree of the surface carbon, expediting the catalyst deactivation. These results provide an insight into the modulation and stabilization of iron carbides by adjusting the interaction between the Fe and supports, which inspires the further development of Fe-based catalysts for FTS applications.
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MOLECULES
·
2025
·Vol. 30
·期 1
·177
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IF 4.6
Zhi Lu,Yifan Guo,Shilin Li,Jiaqi Ding,Yingzi Ren,Kun Tang,Jiefeng Wang,Chengxin Li,Zishuo Shi,Ziqi Sun,Hongbo Meng,Guangxin Wang
Water electrolysis is a promising path to the industrialization development of hydrogen energy. The exploitation of high-efficiency and inexpensive catalysts become important to the mass use of water decomposition. Ni-based nanomaterials have exhibited great potential for the catalysis of water splitting, which have attracted the attention of researchers around the world. Here, we prepared a novel Mo-doped NiFe-based layered double hydroxide (LDH) with a nanoarray microstructure on Ni foam. The doping amount of Mo can significantly change the microstructure of the electrocatalysis, which will further affect the oxygen evolution reaction (OER) performance of water splitting. This novel nanomaterial required only an overpotential of 227 mV for 10 mA cm−2and a Tafel slope of 54.8 mV/dec in 1 M KOH. Meanwhile, there was no Mo, and the NiFe-LDH needed 233 mV to attain to 10 mA cm−2. Compared to the NiFe-LDH without Mo, the NiFeMo-LDH nanosheet arrays exhibited enhanced activities with 17.1 mV/dec less Tafel in OER. The good performance of the electrocatalyst is ascribed to the special nanosheet arrays and the heterostructure of the Ni-Fe-Mo system. These features help to increase the active surface, enhancing the efficient charge transfer and the reactive activity in OER.
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