JOURNAL OF SOLID STATE CHEMISTRY
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2022
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IF 3.656
Rui Zhang,Xue Luo,Feiyu Zhao,Qiang Xu,Yang Xu,Yang Xu,Shuo Chen,Xianping Fan,Xvsheng Qiao
GeSe is a narrow band gap semiconductor with feasible application as infrared photoelectric devices . However, challenges are still maintained to improve their carrier concentration and conductivity for broader scope of photodetector applications. Aiming at such scope, the Ge 1- x Sn x Se (0 < x < 0.2) were synthesized via a facile “one-pot” wet chemical method and a lattice site substitution strategy. Compared to the pure GeSe micro-sheets the synthesized Ge 1- x Sn x Se micro-sheets possessed a smaller band gap (0.914 eV) and a better electrical conductivity (2.80 × 10 −5 Ω −1 cm −1 ), where the former exhibit greatly improved photo-current. The Ge 1- x Sn x Se micro-sheet was then assembled into a photodetector device to demonstrate its remarkable photo responsivities in visible to NIR spectral region (3614 A/W at 532 nm and 86 A/W at 1319 nm). The photo-detection range broadening and the responsivity enhancement can be attributed the carrier concentration increment as well as the band gap narrowing. Therefore, the Ge 1- x Sn x Se micro-sheets can be considered as an excellent candidate that can be applied as high performance photodetectors in the visible to near infrared region.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
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IF 6.953
Wenyu Wang,Huan Sheng,Daihong Cao,Fenglian Zhang,Weifen Zhang,Fang Yan,Dejun Ding,Ni Cheng
Nitric oxide (NO) has aroused wide interest in the treating infected wounds due to its characteristic functionalities. However, its utilization is limited due to its volatile properties, high reactivity, direct potential toxicity, and byproducts of NO donors limited its application. Herein, endogenously NO donor S-nitrosoglutathione (GSNO) was connected covalently to polydopamine nanoparticles (PDA-GSNO NPs) to minimize the loss of NO in aqueous medium. Meanwhile, near-infrared (NIR)-controlled NO release and photothermal therapy (PTT) was obtained through the photothermal conversion by PDA. Then chitosan (CS)/gelatin (GE) biocomposite hydrogel films with preferable biocompatibility, surface hydrophilicity, hydroabsorptivity, and mechanical adhesive properties were constructed. By embedding PDA-GSNO NPs into the films, a multifunctional wound dressing was fabricated. Under NIR light irradiation, the combination of PTT, NO-releasing, and CS antibacterial agents can strengthen the in vitro antimicrobial efficacy and in vivo wound healing activities. Meanwhile, the obtained wound dressing presented good biocompatibility. This work outlines an approach for combating bacterial infections and demonstrating the possibility for synergistic NO-releasing wound healing.
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Materials Advances
·
2022
·Vol. 3
·期 5
·2568-2582
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IF 0
Qing Zhong,Gen Li,Hui Long,Jingxian Zhang,Suiping Deng,Langhuan Huang,Shaozao Tan
Temperature-sensitive hydrogels are always hotspot and have shown great potential in the field of biomedicine. Herein, we report N,N-diethylacrylamide (DEA) temperature-sensitive nanocomposite hydrogels with improved mechanical properties composed of carbon nanotubes (CNT) and glycidyl methacrylate functionalized quaternized chitosan (QCGM), followed by deciphering the synergy between CNT and QCGM for the influence on the properties of the hydrogels. The prepared hydrogels not only present a temperature-stimulus response but also feature in NIR-stimulus response performance due to the addition of CNT. In particular, the DQ0.5C1 hydrogel exhibits the optimal performance, including high mechanical strength and thermal behavior, and was subjected to examine the photothermal conversion ability, as well as loading the model drug ciprofloxacin hydrochloride (CIP) to investigate the drug release and antibacterial ability under different conditions. Moreover, the biocompatibility experiments and the in vivo full-thickness skin defect model results signify that the hydrogels have excellent biocompatibility and also can promote wound closure with accelerated wound contraction and improve the wound-healing process. All in all, the prepared temperature-sensitive nanocomposite hydrogels with improved mechanical properties, high biological safety, and accelerated wound healing have considerable practicability in the fields of drug delivery and wound dressing.
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BIOMATERIALS
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2020
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IF 10.317
Junjie Ren,Lei Zhang,Jiayi Zhang,Wei Zhang,Yang Cao,Zhigang Xu,Hongjuan Cui,Yuejun Kang,Peng Xue
Glucose oxidase (GOx)-mediated starvation circumvents the energy supply for tumor growth, which has been proved as a potent tumor treatment modality. However, tumor hypoxia negatively affects the efficacy of oxygen-involved glucose decomposition reaction . Moreover, curative effect via glucose depletion is not usually satisfactory enough and adjuvant remedies are always required for a promoted tumor ablation. Herein, a multifunctional nanoreactor based on hollow Bi 2 Se 3 nanoparticles was developed by loading oxygenated perfluorocarbon (PFC) and surface modification with GOx, which was exploited for an enhanced tumor starvation and highly sensitive photothermal therapy (PTT). GOx-mediated tumor starvation could impede the adenosine triphosphate (ATP) generation and further downregulate the expression of heat shock protein (HSP) to decrease the thermoresistance of cells. Afterwards, near infrared (NIR) laser irradiation was performed not only to trigger sensitized PTT but also to initiate the release of encapsulated oxygen to relieve local hypoxia. Then, such GOx-mediated tumor starvation would be further amplified, accompanying with secondary enhanced suppression of HSP. Both in vitro and in vivo investigations demonstrated that such nanoreactor can realize a fascinating therapeutic outcome with minimal adverse effects in virtue of the improved synergistic starvation therapy and PTT. Taken together, the proposed treatment paradigm may inspire the future development of more intelligent nanoplatforms toward high efficient cancer therapy.
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高影响因子
Inorganic Chemistry Frontiers
·
2025
·
IF 6.4
Taizhong Xiao,Wen Song,Chongbing Mou,Jinke Wang,Liang Xu,Yongjin Li,Rui Hu,Zhaoyi Yin,Zhengwen Yang,Jianbei Qiu,Zhiguo Song
Crystal field engineering is currently the most significant method for enhancing the near-infrared (NIR) emission intensity and thermal stability of Cr3+ ions. However, this approach is inevitably accompanied by a pronounced blue shift in NIR emission, presenting a considerable challenge for spinel phosphors to achieve efficient and stable long-wavelength NIR emission of Cr3+ ions due to the inherent limitations imposed by a strong crystal field. In this study, we propose a novel pivot-polyhedron linkage engineering strategy based on the LiZnNbO4 (LZNO) spinel crystal to tackle this issue. Supported by the X-ray diffraction (XRD) refinement data, density functional theory (DFT) simulation results and Debye temperature analysis results, our findings reveal that the substitution of [ZnO4] by [MgO4] generates a unique pivot–polyhedron linkage effect. This occurs because the [ZnO4] tetrahedra share angles but not edges with all other polyhedra. Consequently, the simple incorporation of Mg2+ ions leads to a significant increase in NIR emission intensity and thermal stability by enhancing structural rigidity and bandgaps. Simultaneously, this modification allows the weak crystal field of [NbO6] octahedra to be maintained adequately through anomalous lattice expansion and reduced symmetry, which effectively preserves the long-wavelength emission characteristics of Cr3+ ions. The results of our research will establish a distinct structural principle for Cr3+-activated NIR phosphors, facilitating the achievement of exceptional long-wavelength emission and thermal stability.
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高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2025
·Vol. 27
·期 45
·24273-24283
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IF 2.9
Jin Zou,Daoyun Zhu,Zhongfei Mu,Song Xu,Nurahmat Wali,Fugen Wu,Huafeng Dong,Xin Zhang,Xiao Wu,Yifei Luo,Yuchun Zhan
Near-infrared (NIR) spectroscopic technology has shown extensive application prospects. However, developing NIR phosphors with tunability and high thermal stability is a huge challenge. In this work, a highly promising phosphate compound, K3Ga2(PO4)3, has been successfully synthesized. When doped with Cr3+ ions, it is particularly noteworthy that Cr3+ exhibits highly efficient and thermally stable broadband NIR luminescence in the tetrahedral coordination environment. This unique property makes K3Ga2(PO4)3:Cr3+ a compelling candidate for advanced photonic applications. Therefore, studying the luminescent properties of Cr3+ rare earth ions doped into tetrahedral sites is of great significance. In the tetrahedral coordination environment of K3Ga2(PO4)3:Cr3+ ions exhibit broadband near-infrared emission spanning from 700 to 1100 nm (λem = 822 nm, FWHM = 124 nm) under 452 nm blue light excitation. Remarkably, the quantum efficiency reaches as high as 70.9%, demonstrating its exceptional potential for advanced photonic applications. In addition, the phosphors demonstrated exceptional thermal stability with near-zero thermal quenching. The NIR luminescence intensity at 373 K and 423 K retained 109.0% and 90.4% of its initial room-temperature value, respectively. This remarkable performance can be attributed to the material's ultra-wide band gap, and minimal electron–phonon coupling. The NIR pc-LED devices, fabricated by integrating the optimized K3Ga1.93(PO4)3:0.07Cr3+ phosphors with a blue LED chip (λex = 455 nm), achieved a near-infrared output power of 274 mW with a conversion efficiency of 5.42% under a driving current of 100 mA. Experimental results demonstrate that the fabricated NIR pc-LED exhibits significant potential for applications in night vision and vein imaging technologies. This study provides a strategic framework for designing high-performance NIR pc-LED devices, utilizing K3Ga2(PO4)3:Cr3+ as an efficient phosphor-converted light source, and offers valuable insights for practical implementation in advanced optical systems.
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PubMed
高影响因子
DALTON TRANSACTIONS
·
2014
·Vol. 44
·期 1
·237-246
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IF 4.097
Ying Liu,Lining Sun,Jinliang Liu,Yu-Xin Peng,Xiaoqian Ge,Liyi Shi,Wei Huang
A novel mesoporous nanosphere functionalized with 3-(aminopropyl)triethoxysilane (APTES) and 2-(5-bromothiophen)imidazo[4,5-f][1,10]phenanthroline (5-Br-Tip) was synthesized (denoted as Tip-MSS). With the coordinating function of the 5-Br-Tip to lanthanide (Ln) ions, for the first time, LnL3(5-Br-Tip) complexes were linked to the mesoporous nanospheres. The derived materials, named Ln-Tip-MSS (Ln = Eu, Tb, Sm, Nd, Yb), were characterized by Fourier-transform infrared (FT-IR) spectroscopy, TEM, XRD (wide-angle and small-angle), N2 adsorption/desorption analysis, and fluorescence spectroscopy. Upon excitation in the ligand absorption, the Ln-Tip-MSS nanomaterials show characteristic visible (Eu, Tb, Sm) and NIR (Sm, Nd, Yb) luminescence (multicolor emission covered from 450 nm to 1400 nm spectral region). Of importance is that, with low cytotoxicity and good biocompatibility given by the methyl thiazolyl tetrazolium (MTT) assay, the Eu-Tip-MSS was successfully applied to cell imaging in vitro based on the Eu3+ luminescence (under 405 nm excitation).
研究领域:
纳米医学
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生物成像
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材料科学
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分子探针
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化学生物学
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TALANTA
·
2026
·
IF 6.1
Hui Ma,Shaobing Yang,Yuanzhong Wang
The nine-steaming and nine drying process is the traditional preparation method for Polygonatum sibiricum , involving repeated steaming and drying nine times to optimize its dual medicinal and edible value, making it the preferred technique. Though costly, unscrupulous merchants cut corners by reducing production steps to lower costs, yet the differences are nearly undetectable to the naked eye. Therefore, it is urgently necessary to establish a rapid and accurate identification method. This study employed a combination of Fourier transform near-infrared (FT-NIR) spectroscopy and attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy with deep learning to identify nine processed samples of nine steaming and nine drying of Polygonatum kingianum . The results demonstrated that the residual neural network (ResNet) model based on synchronous two-dimensional correlation spectroscopy (2DCOS) images exhibited stable performance and high accuracy. Both the test set and training set achieved an accurate rate of 100 %. Subsequently, to explore the critical factors in different treated samples, we employed principal component analysis (PCA) to interpret the spectral variables and identified that the key variables were related to carbohydrates. Therefore, we analyzed the sugar metabolites of nine treatments using gas chromatography-mass spectrometry (GC-MS) and identified d -Xylulose, d -Ribose, d -Arabinose, and l -Rhamnose as the key metabolites distinguishing the ninth steaming of Polygonatum kingianum . Ultimately, the rapid identification of Polygonatum kingianum processed by the traditional “nine steaming and nine drying” method based on FTIR and deep learning was achieved, and its identification features were analyzed using metabolomics.
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CERAMICS INTERNATIONAL
·
2026
·
IF 6
Wei Xu,Futao Li,Ruichen Xu,Xiaochen Fang,Xiaohui Ruan,Shuru Zhong,Jun Wang,Hai Huang,Cheng Zhang,Biao Zheng
Lead-free double perovskites (DPs) are emerging as sustainable luminescent materials owing to their low-cost synthesis, low toxicity, and superior stability. However, their practical applications are impeded by low luminescence efficiency and a single emission center. To overcome these challenges, we reported a structure-modulation strategy to develop Sb/Er: Cs 2 Na 0 . 95 Ag 0 . 05 YbCl 6 (Sb/Er: CNAYC) DPs by co-doping Cs 2 NaYbCl 6 with Sb 3+ /Er 3+ ions and substituting Na + with Ag + ions. The Sb 3+ /Er 3+ co-doping can introduce multiple emission centers from visible to near-infrared (NIR). Meanwhile, the Na + -Ag + alloying-induced lattice distortion not only enhances the photoluminescence efficiency by breaking the parity-forbidden transitions, but also enables the color of emission to be tuned to the white light range. The Sb/Er: CNAYC DPs simultaneously deliver efficient blue (460 nm@Sb 3+ ), green/red (552/667 nm@ Er 3+ ) and NIR (980/1540 nm@Yb 3+ /Er 3+ ) emissions, providing a promising luminescent material for single-component white/NIR LEDs. Furthermore, the Sb/Er: CNAYC DPs also display pronounced temperature-sensitive fluorescence intensity ratio (FIR) and lifetime characteristics, enabling them well-suited for dual-mode temperature sensing. This study is expected to establish a universal lattice-modulation strategy that yields single-component luminescent materials exhibiting both high-efficiency white/NIR emission and accurate multimode thermometry for next-generation optoelectronic applications.
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Small
·
2026
·
IF 11.8
Yanni Luo,Lixian Huang,Jingjin Zhao,Yuzhen Ma,Xuecai Tan,Fanggui Ye,Shulin Zhao,Shengqiang Hu,Liangliang Zhang
Atherosclerosis (AS) is a risk factor for various cardiovascular diseases (CVD), and early diagnosis and plaque removal are challenges in the management of AS and CVD. To address these challenges, we designed a tungsten‑doped polydopamine nanoparticle (W-PDA NPs). The near-infrared (NIR) optical absorption and enzymatic properties of W-PDA were tuned by adjusting the ratio of W 6+ to PDA. It was found that the W-PDA NPs contain a mixture of W 6+ and W 5+ , which generated large amounts of free electrons, thus conferring both second near-infrared (NIR-II) light absorption capability and superoxide dismutase (SOD)- and catalase (CAT)-like activities. Plaque-targeting was conferred by appending an anti-osteopontin antibody via coordination between carboxyl moieties of the antibody with W 6+ ions on the W-PDA surface. The NIR-II light absorption ability can be utilized for photoacoustic diagnosis of AS, while the SOD- and CAT-like activities facilitate the conversion of superoxide into H 2 O 2 and subsequently O 2 , thereby clearing reactive oxygen species and mitigating inflammation, enabling therapy of AS. Thus, the proposed theranostic agent not only can dynamically report the progression of AS but also can effectively treat AS plaques. This strategy holds broad application prospects in the early and accurate diagnosis and treatment of AS.
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高影响因子
MATERIALS & DESIGN
·
2026
·
IF 8.2
Shaoyou Wang,Quan Zhou,Jiachen Hong,Xinrong Wang,Baocai Zhang,Huihui Wang,Yong Shi,Ayesha Younas,Shuanghu Wang,Shujiao Lu
A CD44-targeted, NIR-II-responsive nanoplatform (CuS@ZIF-8/HA NPs) was developed for TNBC therapy. • Acidic TME triggers ZIF-8 decomposition, releasing Cu 2+ for sustained mitochondrial copper overload. • Cu + drives lipoylated DLAT oligomerization, the core event of cuproptosis. • NIR-II photothermal therapy (55.6 °C) synergizes with cuproptosis for enhanced tumor ablation. • In vivo : pronounced tumor suppression without relapse or toxicity. Triple-negative breast cancer (TNBC) lacks targetable receptors and rapidly expels cytotoxic copper via ATPase copper–transporting alpha/beta (ATP7A/B) pumps, rendering conventional cuproptosis inducers ineffective. We report an acid-activatable, CD44-directed nanoplatform (CuS@ZIF-8/HA NPs) that converts NIR-II irradiation into a synchronized mitochondrial “copper flood–heat shock” event. In the acidic tumor microenvironment, ZIF-8 decomposes and releases Cu 2+ , which is reduced to cytotoxic Cu + , triggering oligomerization of lipoylated dihydrolipoamide S-acetyltransferase (DLAT), the core driver of cuproptosis. Concomitant ferredoxin 1 (FDX1) protein degradation serves as a downstream biochemical marker of cuproptotic injury. The photothermal effect (55.6 °C at 1 W cm −2 ) simultaneously accelerates copper release, amplifies oxidative damage, and ablates cells by hyperthermia. In 4 T1 tumor mice model, eight i.v. doses (10 mg kg −1 ) plus NIR-II light achieved profound tumor suppression without relapse or systemic toxicity, outperforming either monotherapy. Thus, CuS@ZIF-8/HA NPs turns NIR-II light into a spatially confined cuproptotic-photothermal double hit, offering a safe, precise, and translatable strategy against therapy-refractory TNBC. Download: Download high-res image (174KB) Download: Download full-size image
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CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
·
2026
·
IF 10.5
Xingyu Li,Jian Peng,Zihao Xu,Wanyuan Li,Biao Xu,Chunyu Li,Wubin Dai
Simultaneous realizations of high thermal stability and quantum efficiency (QE) in phosphors with near-infrared (NIR) photoluminescence (PL) and long-persistent PL (LPL) attributes are a daunting task. Herein, we have come up with a dual-site co-substitution scheme in Ca 3 Sc 2 Ge 3 O 12 : Cr 3+ /Ni 2+ to concurrently actualize high-quality NIR-I/II (L)PL via either equivalent or aliovalent co-substitution at indirect lattice A/C sites of [Y 3+ + Al 3+ ] or [Y 3+ + Si 4+ ] for [Ca 2+ + Ge 4+ ]. Both Cr 3+ and Ni 2+ are colonized at B site (Sc 3+ ) under weak crystal field environment and emitting continuous PL across NIR-I/II regions via energy transfer from Cr 3+ to Ni 2+ under blue-light excitation. Due to inequivalent replacement of Ni 2+ at Sc 3+ site and consequential production of defects, a charming NIR LPL is also gained. Further incorporation of [Y 3+ + Al 3+ ] unit begets densified robust framework with [Sc(Cr/Ni)O 6 ] octahedral distortion, elucidating the mechanism of improved properties in PL QE (76.23%) and stability (89.5%@423 K). While [Y 3+ + Si 4+ ] modulation in Ca 3 Sc 2 Ge 3 O 12 not only brings rigid structure but also suppresses defects (LPL) because of equivalent triple-unit between Y 3+ /Si 4+ /Ni 2+ and Ca 2+ /Ge 4+ /Sc 3+ . A NIR pc-LED based on the designed phosphor with a commercial 460 nm blue LED chip is fabricated and reveals multi-applications in nondestructive detection, bioimaging, and anticounterfeiting. This work provides new perspectives for developing high-performance NIR-emitting phosphor materials. This study reveals the state-of-the-art researches on both NIR-I/II-emitting (L)PL phosphors with high QE and thermal stability from Cr/Ni-activated in garnet Ca 3 Sc 2 Ge 3 O 12 and their multiple applications in the NIR pc-LED, non-destructive detection, and anticounterfeiting. The proposed A/C-site regulation and ET from Cr to Ni pave a new way to design NIR-I/II phosphor and expands their related optoelectronic applications. Download: Download high-res image (298KB) Download: Download full-size image
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危险品化学品经营许可证（带存储）