BIOSENSORS & BIOELECTRONICS
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2020
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IF 10.257
Juncong Miao,Kang Du,Xuan Li,Xiaoting Xu,Xue Dong,Jinglong Fang,Wei Cao,Qin Wei
Procalcitonin (PCT) as a disease marker is of great significance in the early diagnosis of septicemia and pyemia. Biosensor have good prospects for analysis and detection of disease markers, but developing highly sensitive detection methods for detecting PCT remains a daunting task. In this paper, we develop a ratiometric electrochemical immunosensor with Au NPs modified SiO 2 -Fc-COOH complex as matrix and UiO-66 loaded with Toluidine blue (TB) as a marker for quantitative detection of procalcitonin (PCT). The SiO 2 modified by APTES not only has a large specific surface area but also contains abundant amino groups, which can be connected to the electrochemical probe of ferrocenecarboxylic acid (Fc-COOH). UiO-66 has the advantages of large specific surface area, high porosity and adjustable structure, which can adsorb toluidine blue electrochemical probe through electrostatic attraction . Measurement and analysis of the prepared immunosensor by Differential Pulse Voltammetry (DPV) show that the oxidation peak currents of Fc-COOH and TB appear at potentials of 0.30 V and −0.30 V respectively. As the PCT concentration increases, the oxidation peak current of TB increases and the oxidation peak current of Fc-COOH decreases. The ratios ( ΔI = ΔI TB /ΔI Fc-COOH ) between the double signals could show a certain linear relationship with the concentration of the PCT within a certain range. Under optimal conditions, the linear range of detection obtained by the immunosensor was 1 pg/mL-100 ng/mL and the detection limit was 0.3 pg/mL. In this work, the developed ratiometric electrochemical immunosensor not only provides a simple, reliable and sensitive strategy for quantitative detection of PCT but also provides a useful method for clinical detection of other disease markers.
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PubMed
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Mengmeng Zhang,Wei Zhou,Qingqing Wang,Ning Wang,Xin Wang,Youping Liu,Xin Di
In this work, a novel water compatible core–shell magnetic molecularly imprinted nanocomposite (Fe3O4–COOH@MIPs) was synthesized in an acetonitrile–water reaction system by adopting carboxyl group-functionalized Fe3O4 nanoparticles as the magnetic core, olaquindox as the template molecule and acrylamide as the functional monomer. The resulting Fe3O4–COOH@MIPs was characterized and applied as an adsorbent for magnetic solid-phase extraction (MSPE) of three quinoline-1,4-dioxides (QdNOs). The Fe3O4–COOH@MIPs possessed strong magnetic responsiveness, fast adsorption equilibrium rate (equilibrium within 5 min) and excellent selectivity. By coupling Fe3O4–COOH@MIPs based MSPE with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), good linearity (R2 ≥ 0.9985) and low limits of detection (0.83–5.0 ng L−1) for QdNOs were obtained. Finally, the proposed method was applied to determine trace QdNOs in environmental water samples, and the recoveries were in the range of 68.08–99.88% with RSD less than 12.5%.
研究领域:
环境科学
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分析化学
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纳米技术
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PubMed
高影响因子
CATALYSIS COMMUNICATIONS
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2021
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IF 3.626
Jianan Li,Wenbo Sun,Xinyong Li,Hangfan Ma,Yaxuan Li,Chong Peng
Photocatalysis is an effective means to convert CO 2 and solar energy into high value-added chemicals. Herein, the surface gradient S doped CuCo 2 O 4 microflowers were fabricated by an in situ topotactic engineering strategy. This photocatalyst presented CO 2 photoreduction with a satisfying activity (5 h, 181 μmol) and stability (94.5% retention). Additionally, the theoretical calculations indicated the fomated M-S bond could be favorbale to facilitate the initial CO 2 ⁎ binding and promote the formation of COOH ⁎ intermediates. This work provides a novel strategy for the fabrication of effective photocatalysts and highlights an in-depth understanding of micro-level regulation towards photocatalytic overall performance.
研究领域:
材料科学
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化学
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环境科学
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纳米技术
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高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-9
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IF 14.7
Zhai Jianxin,Xia Zhanghui,Zhou Baowen,Wu Haihong,Xue Teng,Chen Xiao,Jiao Jiapeng,Jia Shuaiqiang,He Mingyuan,Han Buxing
Upcycling of CO 2 into fuels by virtually unlimited solar energy provides an ultimate solution for addressing the substantial challenges of energy crisis and climate change. In this work, we report an efficient nanostructured Ru/MnO x catalyst composed of well-defined Ru/MnO/Mn 3 O 4 for photo-thermal catalytic CO 2 hydrogenation to CH 4 , which is the result of a combination of external heating and irradiation. Remarkably, under relatively mild conditions of 200 °C, a considerable CH 4 production rate of 166.7 mmol g −1 h −1 was achieved with a superior selectivity of 99.5% at CO 2 conversion of 66.8%. The correlative spectroscopic and theoretical investigations suggest that the yield of CH 4 is enhanced by coordinating photon energy with thermal energy to reduce the activation energy of reaction and promote formation of key intermediate COOH* species over the catalyst. This work opens up a new strategy for CO 2 hydrogenation toward CH 4 .
研究领域:
化学
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材料科学
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环境科学
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能源科学
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PubMed
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Molecular Catalysis
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2025
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IF 4.9
Yibo Zhang,Yang Liu,Wei Wang,Chunlai Liu,Hongyu Zhou,Na Wang,Jianglei Hu,Fengwei Shi
Metal-organic framework (MOF)-based composites have received significant attention for catalytic applications and are believed excellent heterogeneous catalysts. In this article, we prepared a new type of material, HPW@MOF-199/SBA-15C (PMS-15C). For this material, the MOF-199 encapsulating Keggin-type phosphotungstic acid (HPW) was grown inside the pores of the SBA-15 functionalized by carboxylic acids. The N 2 adsorption-desorption isotherms and pore size distributions, X-ray powder diffraction, transmission electron microscopy, and scanning electron microscopy analyses showed that the PMS-15C composites had an ordered two-dimensional hexagonal mesoporous structure, in which HPW encapsulating by MOF-199 loaded into the SBA-15C. Fourier-transform infrared spectroscopy and X-ray photoelectron spectroscopy indicated that HPW was successfully loaded, and the Keggin structure of HPW in PMS-15C remained unchanged. With the reaction of acetic acid and ethanol, the catalytic performance of PMS-15C was studied. Under the optimal conditions, ethyl acetate yield reached 81.4 %. The forward reaction rate was 0.432 mL mol −1 min −1 , and the activation energy was 38.35 kJ mol −1 . And the data were found to be consistent with the second-order reversible reaction kinetic model. The catalytic activity of the PMS-15C-0.2 composites remained stable after five catalytic cycles. In addition, the esterification of n-octanol/acetic acid and ethanol/oleic acid were studied using PMS-15C-0.2 as the catalyst. The results suggested that the catalytic activity of PMS-15C-0.2 was weakened upon increasing the substrates’ alkyl chain length.
研究领域:
材料科学
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催化化学
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JOURNAL OF MEMBRANE SCIENCE
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2025
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IF 9
Zhiyuan Huang,Ye Yuan,Weifan Wang,Hao Zheng,Zhi Wang
Mixed matrix membranes (MMMs) have demonstrated remarkable advantages in gas separation applications through the synergistic integration of polymeric matrices and nanostructured reinforcements. While these advanced composite thin-film materials exhibit substantial potential for CO 2 separation, their industrial-scale implementation confronts threefold challenges: elevated manufacturing costs, interfacial compatibility optimization between nanofillers and polymer matrices, and performance enhancement requirements for achieving superior separation efficiency. In this study, the green and economical nanofiller UIO-66-(COOH) 2 (denoted as UC) was strategically selected. A novel strategy involving synergistic modification using Zn 2+ and polyvinylamine (PVAm) was developed to address the critical challenge of severe particle agglomeration and sedimentation. This phenomenon, caused by intense electrostatic interactions between the strongly negatively charged UC and the cationic polymer PVAm during surface modification, was effectively mitigated through the proposed cooperative modification mechanism, resulting in the successful synthesis of P@UC-Zn exhibiting exceptional dispersibility and enhanced compatibility with the polymeric matrix. The fabricated P@UC-Zn-PVAm/mPSf MMMs containing 35 wt% filler exhibited remarkable CO 2 permeance (3250 GPU) and selectivity (166) under feed gas conditions (CO 2 /N 2 = 15/85 vol%, feed pressure: 2 bar). Furthermore, the optimized MMMs demonstrated robust operational stability in simulated flue gas tests and showed potential for applications in carbon dioxide-methane and carbon dioxide-hydrogen separations.
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JOURNAL OF MEMBRANE SCIENCE
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2017
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IF 6.035
Chunli Liu,Hongchao Mao,Jifu Zheng,Suobo Zhang
Carboxylated cardo poly(arylene ether ketone)s (PAEK-COOH) is a thermally stable and hydrophilic membrane fabrication material. Herein, PAEK-COOH was employed as membrane material, being dissolved in N-methyl-2-pyrrolidone (NMP) and 1,4-dioxane (DO) mixed solvent and activated by adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS) to prepare polymer casting solution . Then the activated polymer film was immersed into polyethylenimine (PEI) aqueous solution that served as coagulation bath for taking the one-step chemical reaction-involved phase inversion process. As illustrated by the SEM images, the fabricated crosslinked tight ultrafiltration membrane had a dense and integrally skinned separation skin layer. Chemical composition and hydrophilicity of membrane surface were studied by ATR-FTIR and water contact angle , respectively. Those results revealed that, via the in situ crosslinking of activated carboxylic acid group and PEI along with the phase inversion process, the PEI molecules had been covalently bonded onto membrane surface and resulted in the increase of membrane hydrophilicity. The optimized membrane had a molecular weight cut off (MWCO) of 12.7 kDa and an isoelectric point of 7.4, indicating which is slightly positively charged. The one-step chemical reaction involved phase inversion between reactive macromolecules, i.e., activated PAEK-COOH original polymer film and PEI crosslinker in coagulant, was an efficient and convenient approach for fabrication of highly permeable and selective tight ultrafiltration membranes. Membrane had a dye solution permeability of 80–84 L m −2 h −1 bar −1 and Congo red (CR) rejection of 99.9% in 100 h long-term filtration testing, being capable for dye removal from textile wastewater .
研究领域:
材料科学
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环境工程
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高影响因子
ACS Applied Materials & Interfaces
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2022
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IF 10.383
Qi Liang,Bin Jiang,Na Yang,Longfei Zhang,Yongli Sun,Luhong Zhang
The integration of membranes with additives such as functionalized nanomaterials can be recognized as an effective method to enhance membrane performance. However, to obtain an efficient nanoparticle-decorated membrane, the compatibility of nanomaterials remains a challenge. Hydrophilic carboxylated covalent organic frameworks (COF–COOH) might be expected to avoid the drawbacks of aggregation and easy shedding of inorganic materials caused by the poor interfacial compatibility. Herein, a highly compatible dip-coating strategy was proposed for the superhydrophilic modification of polyvinylidene fluoride membrane via COF–COOH integrated with dopamine. COF–COOH together with polydopamine nanoparticles were uniformly and stably attached to the membrane due to the high interfacial compatibility, constructing a coating with rough hierarchical nanostructures and abundant carboxyl groups. The synergistic effects of multiscale structures and chemical groups endow the membrane with superhydrophilicity and underwater superoleophobicity, the water contact angle decreased from 123 to 15°, and the underwater oil contact angle increased from 132 to 162°. Accordingly, the modified membrane exhibits an ultrahigh oil rejection ratio (>98%), a high flux (the maximum reaches 1843.48 L m–2 h–1 bar–1), attractive antifouling ability, and impregnable stability. This work would provide a momentous reference for the application of COF–COOH in practical oily wastewater treatment.
研究领域:
材料科学
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环境工程
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高影响因子
GREEN CHEMISTRY
·
2023
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IF 9.8
Yuhua Chen,Chengqi Feng,Chenkai Jin,Yuxin Zhu,Juncheng Huang,Haining Na,Jin Zhu
Pyruvaldehyde as a carbon source is synthesized together with boric acid to produce a carbon-based solid catalyst with in situ bifunctional groups of adsorptive boron hydroxyls and carboxyls in a single-step hydrothermal carbonization process, which is mainly utilized to induce the hydrolysis of cellulose to sugar in pure water. The obtained catalyst exhibits a strong adsorption capacity of 532 mg g−1 with cotton cellulose and possesses good water dispersibility. It can effectively break the aggregated structure of cellulose through the strong interfacial adsorption interaction to induce the hydrolysis of cellulose to sugar with high efficiency in the pure aqueous system. The cellulose conversion and the glucose yield reach 97.3% and 40.0%, respectively. Additionally, the catalyst demonstrates excellent hydrothermal stability and reusability. As a result, a high-yield, acid-free, green, and environmentally friendly hydrolytic process of cellulose to sugar in pure water is successfully established.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2022
·
IF 4.598
Wei Zhong,Jin Zou,Yanyu Xie,Jing Yang,Mingfang Li,Shuwu Liu,Yansha Gao,Xiaoqiang Wang,Limin Lu
Herein, a highly sensitive and selective electrochemical sensor for the detection of benomyl (BN), a typical benzimidazole fungicide was proposed based on hierarchical nano-Cu x O decorated MWCNTs-COOH/MXene (nano-Cu x O-MWCNTs-COOH /MXene) composite. The ternary heterostructure presents good electrical conductivity, large specific surface area, and high catalytic activity, exhibiting excellent electrocatalytic activity with enhanced electrochemical signals towards the oxidation of BN. Besides, the embedded nano-Cu x O particles possess strong affinity toward benzimidazole molecules, which could promote the preconcentration of BN, further enhancing the sensitivity, as well as ensuring the high selectivity. Benefitting from the synergistic effect of components in the composite, the developed sensor presents a broad linear range from 10.0 nM to 10.0 μM with a low limit of detection of 3.0 nM (S/N = 3). Meanwhile, the nano-Cu x O-MWCNTs-COOH/MXene electrode also displays good long-term stability and repeatability. Furthermore, this method was successfully applied for the detection of BN in apple samples, illustrating its promising practicability.
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TALANTA
·
2017
·
IF 4.162
Xiaofang Ma,Yali Wu,Samrat Devaramani,Caizhong Zhang,Qixia Niu,Mahgoub Ibrahim Shinger,Wenqi Li,Duoliang Shan,Xiaoquan Lu
The GO-COOH/AuNPs/ZnAPTPP nanocomposites were constructed using zinc monoamino porphyrin (ZnAPTPP) through π–π conjugation with carboxylated graphene oxide (GO-COOH) loaded with Au nanoparticles (AuNPs). Prepared materials were characterized by 1 H NMR spectra, UV–vis absorption spectroscopy and electrochemical impedance spectroscopy . ITO electrode surface was modified with the prepared nanocomposites showed a good photocurrent response when the bias potential, −0.1 V was applied. Nanocomposites modified ITO electrode exhibited good photo-response to the 4-nitrophenol (4-NP). ZnAPTPP were excited from HOMO to LUMO under light irradiation , the photoexcited electrons injected into the conduction band of GO-COOH, and then transferred to AuNPs further to the ITO. The presence of GO-COOH and AuNPs improved the separation of photogenerated charges due to their synergetic effect and excellent conductivity. Externally added 4-NP scavenges the photogenerated holes i.e. it acts as a sacrificial electron donor thereby it enhances the photocurrent of the system. Based on this interaction, a novel method for photoelectrochemical detection of 4-NP was developed with a linear range from 0.1 to 15 nmol/L (r = 0.996) and detection limit of 0.04 nmol/L (S/N = 3). Proposed method is simple and sensitive and this was successfully applied for the quantification 4-NP in river water sample matrices.
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ACS Applied Polymer Materials
·
2025
·
IF 4.7
Kai Gou,Minghui Wei,Jingzhi Tang,Yijing Nie,Gengsheng Weng
Shape-morphing polymer hydrogels that mimic humidity-change-triggered shape transformations are of interest for developing soft robotics and actuators. Yet, covalent cross-links limit accessible curvature for three-dimensional shape-morphing, especially when generating Gaussian curvatures on two-dimensional (2D) thin plates. Herein, we demonstrate a bilayered shape-morphing polymer material composed of a thermoplastic polymer passive layer and a poly(acrylic acid) hydrogel active layer cross-linked only by Fe3+-COOH coordination bonds (PAA/Fe), which exhibited remarkable Gaussian curvature shape deformation on a 2D thin polymer film. The PAA/Fe hydrogel first underwent anisotropic dehydration and then swelled in water to achieve shape-morphing. During the entire shape-morphing process, the well-maintained stiffness and elasticity of the PAA/Fe hydrogel provide sufficient internal stress to drive deformation. This anisotropic dehydration-mediated hygroscopic expansion-triggered shape-morphing can be applied for printable and rewritable patterning, soft gripping, and impact resistance. The alternating assembly of the PAA/Fe hydrogel and covalent hydrogel sheets on a thermoplastic film enables various wavy-shaped hygroscopic shape transformations with potential actuation and impact resistance applications. Our work demonstrates a design strategy to fabricate shape-morphing materials with potential applications in multifunctional soft robotics and actuators.
研究领域:
材料科学
·
高分子科学
·
软体机器人
·
水凝胶
·
机械工程
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高影响因子
危险品化学品经营许可证（带存储）