Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Weirui Chen,Weijie Chen,Yimin Luo,Yanqi Feng,Xukai Li,Jing Wang,Ping Li,Liying Bin,Bing Tang,Laisheng Li
g-C 3 N 4 (CN) based catalysts were effective for photocatalytic ozonation (PCO), but their stability during reaction remained a mystery. This study investigated the change on PCO activity and stability of CN induced by F or I doping. Compared with CN, F-CN had the greater VB potential while I-CN had a greater CB position, which both led to their better O 3 activation. F-CN and I-CN PCO showed the greater oxalic acid (OA) degradation than that of CN PCO process. Though the enhanced activity, both F-CN and I-CN demonstrated the lower stability compared with that of CN. Because of the existing of reactive oxygen species (ROS) like •OH, •O 2 - and h vb + , CN, F-CN and I-CN were partially oxidized, generating NO 3 - and organic molecules such as cyanuric acid. h vb + and •OH mainly accounted for the decomposition of three CN. Triazine ring oxidation resulted in internal tearing and edge fracture as well as the formation of O-containing groups on all CN-based catalysts. O contents in catalysts initially increased and then decreased with reaction time, indicating that surface O-containing groups were unstable. The structural destroy could be eased with the present of organic pollutants. This study deepened the understanding of fate of CN based catalysts during PCO application.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2017
·
IF 3.359
Fuyin Ma,Zheng Li,Haogui Zhao,Yiyun Geng,Wei Zhou,Qingnuan Li,Lan Zhang
As a new carbon-based membrane material used for ionic and molecular sieving, the graphene oxide (GO) membrane also has potential application in radiochemical separation. In this work, the permeation performances of some typical metallic elements in high level-liquid waste (HLLW) through the ionic sieving 5-μm-thick GO membranes were investigated. It was found that the permeation rates of ions through GO membranes markedly decreased with the increase of hydrated ionic radii. Cs(I) and Sr(II) permeated through GO membranes quickly, whereas lanthanide ions and actinide ions infiltrated much more slowly, thus providing the feasibility of separation according to the difference of hydrated ionic radii. Moreover, the concentrations of initial metal ions and acidity in feed solutions also had influences on the permeation of ions through GO membranes, and higher initial metal ions and feed solution acidity were favorable to the removal of Cs(I) and Sr(II). The barrier separation test indicated that GO membranes had promising ability for the separation of Cs(I) and Sr(II) from lanthanide and actinide ions due to the difference of hydrated ion radius, and the separation factor of Cs(I)/U(VI) and Sr(II)/U(VI) would reach about 10 and 3 in single penetration. The presented results demonstrated that the membrane separation based on GO membrane would be a promising candidate for the removal of Cs(I) and Sr(II) from HLLW.
研究领域:
放射化学
·
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Yiping Guo,Wei Xie,He Li,Jianping Li,Jun Hu,Honglai Liu
The adsorption desulfurization (ADS) is a promising technology for deep removing thiophene-type sulfurs, yet it remains challenges in maintaining good performance for real applications in the presence of water. Guided by theoretical calculations, we constructed hydrophobic selective channels by crosslinking porous aromatic framework (PAF) of PAF-56 on the surface of adsorbent MOF-199 with Cu nodes reduced. The optimized Cu(I)-BTC@PAF30 shows a high saturated dibenzothiophenes (DBT) adsorption capacity of 61.7 mgS g −1 from the dehydrated model oil. Attributed to the good DBT-affinity (with binding energy (BE) of −90.52 KJ mol −1 ) and water-repulsion (with BE of −14.72 KJ mol −1 ), PAF-56 coating layer significantly improves the hydrophobicity , and keeps the DBT adsorption capacity as high as 50.8 mgS g −1 in the presence of 0.5% (v/v) water, the decline of 17.6% was much smaller than the dramatical 70.9% decrease in pristine Cu(I)-BTC. More importantly, it effectively prevents Cu(I) nodes from the oxidation , and exhibits a superior stable cyclic performance with the removal efficiency above 91% after 20 cycles. Therefore, Cu(I)-BTC@PAF30 can be a good representative of this surface modification strategy to achieve promising application in industrial ADS.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2019
·
IF 6.35
Xinfeng Zhang,Xiaoya Fan,Yanying Wang,Fengjie Lei,Lin Li,Juewen Liu,Peng Wu
Aggregation of plasmonic gold nanoparticles (AuNPs) has been widely used for label-free colorimetric sensing. Adding salt is a commonly used method to induce a color change, but salt-induced aggregation by charge screening is a slow kinetic process, making quantitative and reproducible measurement difficult. Herein, we explored an alternative method by charge neutralization using positively charged molecules, such as a DNA-staining dye, SYBR Green I (SG), for efficient and stable assembly of AuNPs. Even submicromolar SG effectively triggered the aggregation of AuNPs in less than 1 min, and the resulting intense blue color was stable for over 10 h. The charge neutralization effect of SG was confirmed with zeta potential measurements. Besides, pH-dependent aggregation of AuNPs by SG agreed well with the pKa of the nitrogen atoms responsible for the positive charges in the SG structure. Moreover, the charge neutralization effect was also observed from polycations such as polyamines. The SG-induced assembly of AuNPs was developed into a label-free colorimetric sensing platform. Benefiting from the intense blue color, this new sensing strategy allowed visual detection of as low as 0.1 nM DNA, 50-fold lower than that by salt. Such a charge neutralization strategy may inspire further thinking on fundamental colloidal science and its applications in analytical chemistry. This work itself significantly improved AuNP-based colorimetric sensors in terms of detection time, signal stability, and sensitivity.
研究领域:
分析化学
·
胶体科学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Marine Drugs
·
2017
·Vol. 15
·期 7
·217
·
IF 3.503
Lan-Ting Xin,Lu Liu,Chang-Lun Shao,Ri-Lei Yu,Fang-Ling Chen,Shi-Jun Yue,Mei Wang,Zhong-Long Guo,Ya-Chu Fan,Hua-Shi Guan,Chang-Yun Wang
Currently, DNA topoisomerase I (Topo I) inhibitors constitute a family of antitumor agents with demonstrated clinical effects on human malignancies. However, the clinical uses of these agents have been greatly limited due to their severe toxic effects. Therefore, it is urgent to find and develop novel low toxic Topo I inhibitors. In recent years, during our ongoing research on natural antitumor products, a collection of low cytotoxic or non-cytotoxic compounds with various structures were identified from marine invertebrates, plants, and their symbiotic microorganisms. In the present study, new Topo I inhibitors were discovered from low cytotoxic and non-cytotoxic natural products by virtual screening with docking simulations in combination with bioassay test. In total, eight potent Topo I inhibitors were found from 138 low cytotoxic or non-cytotoxic compounds from coral-derived fungi and plants. All of these Topo I inhibitors demonstrated activities against Topo I-mediated relaxation of supercoiled DNA at the concentrations of 5–100 µM. Notably, the flavonoids showed higher Topo I inhibitory activities than other compounds. These newly discovered Topo I inhibitors exhibited structurally diverse and could be considered as a good starting point for the development of new antitumor lead compounds.Keywords:virtual screening;molecular docking;Topo I inhibitor;low toxic;natural product
研究领域:
药理学
·
分子生物学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2017
·
IF 2.714
Yong Cheng,Feifei Sun,Qichun Feng,Qiang Zhao,Yinghua Zhou
In this study, we describe the successful fabrication of silver nanoparticles (AgNPs) within Ag(I)-AMTD metal-organic gel matrix. The resulting composite (AgNPs@Ag(I)-AMTD) was characterized by 1 H NMR, IR, SPR, SEM, TEM, EDX, XPS, and XRD. This material exhibited a remarkable and durable activity for the catalytic reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) and other nitroarenes by NaBH 4 in aqueous solution. This method affords a facile means of embedding the active silver nanoparticles within the metal-organic gel matrix and offers the necessary stability of the resulting silver nanostructure for catalytic transformation.
研究领域:
材料科学
·
催化化学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Shuai Wang,Anzhe Wang,Pan Gao,Rui Bai,Junjie Liu,Peng Zhou,Dazhao Liu
Strength prediction under the action of pores is crucial for the safety of ceramics. Here, a quantitative prediction model of pore-strength response under mode-I loading was developed based on the new mapping relationship between stress intensity factor and tip radius. The new model was proved to have great application after comparison and analysis of the pore-strength test data of three typical ceramics as well as the pertinent data as-reported in the literature. Results indicated that when the tip radius of pore ( ρ ) exceeds the critical value ( ρ c = K Ic 2 /(π σ 0 2 )), the stress intensity factor increases as a power function with increasing ρ , at which point the strength decay is significantly weakened, and when the ρ is lower than the ρ c , the pore can be equated to a crack problem. This work can not only forecast and assess the failure strength of ceramics containing pores, but also provide guidance for the design of extremely dependable ceramics.
研究领域:
材料科学
·
力学工程
✓ 已验证
产品关联
DOI
高影响因子
Microorganisms
·
2023
·Vol. 12
·期 1
·38
·
IF 4.5
Kun Geng,Ying Lin,Xueyun Zheng,Cheng Li,Shuting Chen,He Ling,Jun Yang,Xiangyu Zhu,Shuli Liang
Acetaldehyde is an important carbonyl compound commonly detected in wines. A high concentration of acetaldehyde can affect the flavor of wines and result in adverse effects on human health. Alcohol dehydrogenase I (ADH1) inSaccharomyces cerevisiaecatalyzes the reduction reaction of acetaldehyde into ethanol in the presence of cofactors, showing the potential to reduce the content of acetaldehyde in wines. In this study,ADH1was successfully expressed inPichia pastorisGS115 based on codon optimization. Then, the expression level ofADH1was enhanced by replacing its promoter with optimized promoters and increasing the copy number of the expression cassette, with ADH1 being purified using nickel column affinity chromatography. The enzymatic activity of purified ADH1 reached 605.44 ± 44.30 U/mg. The results of the effect of ADH1 on the content of acetaldehyde in wine revealed that the acetaldehyde content of wine samples was reduced from 168.05 ± 0.55 to 113.17 ± 6.08 mg/L with the addition of 5 mM NADH and the catalysis of ADH1, and from 135.53 ± 4.08 to 52.89 ± 2.20 mg/L through cofactor regeneration. Our study provides a novel approach to reducing the content of acetaldehyde in wines through enzymatic catalysis.Keywords:alcohol dehydrogenase I;Pichia pastoris;cofactor regeneration;multicopy;acetaldehyde;wine
研究领域:
微生物学
·
生物技术
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2023
·Vol. 11
·期 12
·6168-6180
·
IF 11.9
Yifan Chen,Jinze Wang,Youran Hong,Yusi Yang,Lulu Tan,Nan Li,Can Ma,Jiangwei Wang,Xiulin Fan,Yujie Zhu
Recently, to enhance the low-temperature performance of lithium-ion batteries (LIBs), significant efforts have been devoted to developing novel electrolytes with low viscosities, high conductivities, and facile Li-ion desolvation, while much less attention is paid to exploring optimum electrode materials for low-temperature LIBs. In this contribution, we discover that commercial microsized Cu2S exhibits a remarkably high performance toward lithium storage under ultra-low temperatures. Under room temperature, it delivers a reversible specific capacity of 318.8 mA h g−1 with very flat lithiation–delithiation plateaus around 1.75 V in Li metal cells. At −60 °C and a galvanostatic charge–discharge rate of 0.3C, it could still provide a reversible specific capacity of 168.8 mA h g−1 with stable cycling performance, promising its application in ultra-low-temperature Li-based batteries. Through a combination of microscopic, spectroscopic, and electrochemical characterization bolstered by theoretical calculations, the detailed reaction mechanisms and mechanistic understanding of the excellent low-temperature performances are proposed. This work points out the great opportunities to enhance the low-temperature performance of LIBs by discovering suitable electrode materials.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
PHYTOMEDICINE
·
2022
·
IF 6.656
Qianqian Jiang,Xu Chen,Xue Tian,Jingmei Zhang,Siming Xue,Yanyan Jiang,Tiantian Liu,Xiaoping Wang,Qianbin Sun,Yiqin Hong,Chun Li,Dongqing Guo,Yong Wang,Qiyan Wang
Background Doxorubicin (DOX) is a powerful anti-tumor anthracycline drug . However, its clinical use is limited due to the side effect of cardiotoxicity . Tanshinone I (Tan I) is one of the major tanshinones isolated from Salvia miltiorrhiza . Studies have shown that Tan I is effective in the treatment of cardiovascular diseases. However, the potential effects of Tan I against DOX-induced cardiotoxicity (DIC) have yet to be explored. Purpose This study aimed to explore whether Tan I can protect against DIC and to reveal whether Tan I can exert anti-oxidative effect by regulating nuclear erythroid factor 2-related factor 2 (Nrf2) pathway. Methods DIC models were established in vivo by intravenous injection of DOX. Echocardiography was used to monitor the cardiac function of mice. Transmission electron microscopy was used to assess mitochondrial damage. Oxidative stress was measured by dihydroethidium (DHE) staining and western blotting . The accumulation and nuclear translocation of Nrf2 was detected by immunofluorescence. H9C2 cellular DIC model was established in vitro to explore the pharmacological mechanism. Nrf2 small interfering (si)-RNA was applied to H9C2 cells to explore whether Tan I exerted protective effect against DIC through Nrf2 signaling pathway . The protective effects of Tan I on mitochondrial function and mitochondrial membrane permeability were measured by MitoSOX™ Red and JC-1 staining assays, respectively. Results In vivo experiments revealed that Tan I could improve cardiac function and protect against DOX-induced myocardial structural damages in mice models. The oxidative stress induced by DOX was suppressed and apoptosis was mitigated by Tan I treatment. Tan I protected against DOX-induced mitochondrial structural damage. Meanwhile, key proteins in Nrf2 pathways were upregulated by Tan I treatment. In vitro studies showed that Tan I attenuated DOX-induced generation of reactive oxygen species (ROS) in cultured H9C2 cells, reduced apoptotic rates , protected mitochondrial functions and up-regulated Nrf2 signaling pathway. Tan I promoted accumulation and nuclear translocation of Nrf2 protein. In addition, interference of Nrf2 abrogated the anti-oxidative effects of Tan I and reversed the expressions of key proteins in Nrf2 pathway. The protective effects of Tan I on mitochondrial integrity was also mitigated by Nrf2 interference. Conclusion Tan I could reduce oxidative stress and protect against DIC through regulating Nrf2 signaling pathway. Nrf2 is a potential target and Tan I is a novel candidate agent for the treatment of DIC.
研究领域:
药理学
·
心血管疾病
·
分子生物学
·
细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2022
·
IF 11.504
Weiwei Hu,Huan Cheng,Dongmei Wu,Jianle Chen,Xingqian Ye,Shiguo Chen
The rhamnogalacturonan I (RG-I) region of pectin shows health benefits and novel gel applications. Commercial pectin is extracted from citrus peel in most instances, whereas they are homogalacturonan (HG)-dominated productions and the methods to extract pectin targeting RG-I are limited. To take full advantage of citrus wastes and upgrading this pectin resources, a new extraction method based on a diluted NaOH assisted by a combination of ultrasound (US) and pressure, namely manosonication (MS), was established for RG-I enriched pectin extraction. MS significantly enhanced the pectin yield (21.47 ± 0.11%) while reducing the use of NaOH reagents (50 mmol/L) and processing time (50 min). Structurally, the MS (300 kPa) resulting products achieved nearly a 2-fold greater RG-I content (58.61 mol%) than that of commercial pectin (30.12 mol%). Moreover, for the investigation of the extraction mechanism, external pressure enhanced the cavitation effect, as the calorimetric intensity increased from 1.28 W/mL (100 kPa) to 3.3 W/mL (350 kPa). A sufficient ultrasonic mechanical action allowed for obtaining RG-I enriched products with large molecular weight (9.506 × 10 4 –2.813 × 10 5 ) and low degree of methoxylation. Transmission electron microscopy (TEM) and scanning electron microscopies (SEM) verified the increased disintegration of the cell wall tissue by MS. Raman imaging and immunofluorescence labeling suggested the synergistic effect of pressure and ultrasound on enhancing the yields and RG-I content. This new method provided alternations in functional polysaccharides extraction, and the yield and structure of citrus RG-I enriched pectin strongly indicates the potentials of MS in other RG-I rich vegetables applications.
研究领域:
食品科学
·
植物化学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2015
·
IF 4.097
Ling Wang,Ran Yang,Jianjun Li,Lingbo Qu,Peter de B. Harrington
In this work, a very sensitive electrochemical sensor for Sudan I was established based on nanohybrids of graphene-ZnSe quantum dots . Positively charged cetyltrimethyl-ammonium bromide (CTAB) functionalized graphene was used as a template-directed building block to self-assemble negatively charged ZnSe quantum dots (QDs). The hybrids of ZnSe-CTAB-graphene exhibited strong enrichment effect on Sudan I and gave superior electrocatalytic activity towards the oxidation of Sudan I. Applying differential pulse voltammetry (DPV), the peak current of Sudan I is proportional to its concentration in the range from 0.004 to 2.0 μM and 2.0 to 15.0 μM. This report is the first on applying graphene-ZnSe hybrids for electrochemical sensing.
研究领域:
分析化学
·
纳米技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）