APPLIED ORGANOMETALLIC CHEMISTRY
·
2022
·Vol. 36
·期 6
·e6693
·
IF 4.072
Jiale Liu,Mengyao Huang,Zhongyu Hua,Jiatong Ni,Yi Dong,Zeran Feng,Tiedong Sun,Chunxia Chen
Chemodynamic therapy (CDT) uses the conversion of H 2 O 2 to ·OH triggered by Fenton-like reactions to treat tumors, but the treatment is not complete due to insufficient intracellular H 2 O 2 content. Photothermal therapy (PTT) uses photothermal materials for photothermal conversion to kill tumors, but it is limited by the extent of exogenous light transmission and cannot achieve satisfactory therapeutic effects. Therefore, designing a composite nanomaterial that amplifies CDT and couples it with PTT for tumor treatment is a major challenge. Herein, we designed a W-POM NCs@HKUST-1 nanoplatform that combines PTT and CDT and has better targeting properties. It shows high stability and photothermal conversion efficiency under the irradiation of near-infrared light and efficiently catalyzes the generation of intracellular hydroxyl radicals, this composite material exhibits higher lethality than single therapeutic strategies. This study expands the application area of POM@MOF composite nanomaterials and provides a promising means of enhanced tumor therapy.
研究领域:
纳米技术
·
癌症治疗
·
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Qunfeng Chen,Daobin Tang,Qi Zhang,Zhiyuan Tang,Longlong Ma,Xinghua Zhang
Electron-metal support interactions (EMSI), which can tailor the microenvironment through electron transfer and coordination structure design, are an effective strategy to augment the intrinsic catalytic activity of catalysts. However, it remains challenging to establish the interfacial structure and interfacial electron configuration of catalysts to precisely regulate and enhance EMSI. In this work, the spatially defective sites and specific electronic states of Pd-UiO-66 were modified by in-situ constructing a W-O-Zr interface to strengthen the EMSI between Pd nanoparticles (Pd NPs) and UiO-66 support via implanting W into the defective Pd-UiO-66, realizing the effective hydrodeoxygenation (HDO) of vanillin (VAN) at room temperature (RT). The as-prepared catalyst Pd-UiO-66–0.24 W achieved > 99 % conversion of VAN and > 99 % yield of 2-methoxy-4-methylphenol (MMP) within 12 h, which surpassed the previous reports. The DFT analysis revealed that the narrow band-gap energy between Pd-UiO-66–0.24 W and H 2 molecule, along with the σ or π coordination adsorption between p and d orbitals of the implanted W and O in C=O, facilitated the activation of the H 2 molecules and reactant molecules. In addition, the constructed electron-deficient W-O-Zr interfacial sites provided more acidic sites that favor the cleavage of C-O bonds, promoting the HDO process of VAN. This work provides important insights into the modulation of EMSI, structural defects and acidic sites of metal–organic frameworks (MOFs)-based catalysts for efficient HDO of lignin-derived oxygenated compounds.
研究领域:
催化化学
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材料科学
·
理论计算化学
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Han-Bing Gao,Yue-Lun Wang,Dao-Ran Liu,Jin-Xuan Xie,Le-Le Qiu,Jian Xiao,Jing Liang,Fang-Jing Liu,Yun-Peng Zhao
Achieving high efficiency and selectivity in cleaving aryl C–O bonds is critical for lignin valorization and the production of aromatic chemicals. A green and sustainable approach has been developed using bimetallic Ni–W catalysts, which controlled the hydrogen supply and mediated hydrogen transfer via in situ hydrogen donors. An appropriate W/Ni ratio is essential for enhancing the supply of active hydrogen, the adsorption capacity for reactive molecules, and the efficiency of hydrogen transfer, thereby optimizing the overall catalytic performance. A comprehensive investigation was conducted on the factors influencing the catalytic transfer hydrogenolysis of lignin derivatives, focusing on the reaction temperature, solvent, hydrogen source, pressure, and duration. Under optimal conditions (180 °C, 1.0 MPa N2, and <2.5 h), various lignin-derived aryl ethers achieved complete conversion with 100% monomer selectivity. This study demonstrated the excellent reusability of the Ni–W catalyst for four cycles. More significantly, the mechanisms underlying active hydrogen transfer, transfer hydrogenolysis, and bimetallic interactions were elucidated. The integration of Ni and W species significantly enhanced the synergy among active metal sites, oxygen defects, and acid sites. This synergistic mechanism enabled H• and H+ to function as the primary active hydrogen species. Furthermore, the in situ generation and targeted migration of H• radicals and H+ ions facilitated the preferential cleavage of C–O bonds over the hydrogenation of aromatic units within lignin, leading to the formation of high-value aromatic monomers.
研究领域:
催化化学
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可再生资源转化
·
绿色化学
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产品关联
DOI
高影响因子
ACS Applied Bio Materials
·
2018
·
IF 0
Xingzhong Zhang,Yixiang Wang,Xiaogang Luo,Ang Lu,Yan Li,Bin Li,Shilin Liu
The increased quantities of fat in plants could allow the cells to inhibit the growth of ice and thus prevent the damages of their tissue structure in winter. In view of the structural buildup of freezing tolerance mechanism, here we presented a facile way of employing O/W Pickering emulsion as a template to produce the freestanding organo-hydrogels with increased mechanical stability and energy storage capacity. The oil droplets stabilized by cellulose nanofibrils were dispersed in the alginate polymer network that cross-linked with Ca2+, which resulted in homogeneous and closely packed microstructures. The prepared organo-hydrogels could maintain original gel structure under frozen conditions and had extraordinary mechanical performance. It could endure compressive stress up to 35 KPa (at 50% strain) and the elastic modulus was around 72 KPa, while the solid content of polysaccharides was only about 0.75%. By using our comprehensive strategy, organo-hydrogels with higher volumes of oil phase exhibited an enhanced cold storage capacity. For alginate hydrogel, it took 8 min when the temperature rose from 0 to 5 °C, while for the organo-hydrogel with oil volume of 30%, it took about 24 min. After 34 min, the inner temperature of alginate hydrogel was close to 25 °C, and about 70 min were needed for the temperature of organo-hydrogel to reach 25 °C. This kind of gel materials with complementary heteronetworks not only will have potential applications in cold chain logistics, but also can be applied in other fields with unusual functions.
研究领域:
材料科学
·
化学工程
·
生物技术
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产品关联
DOI
PubMed
MATERIALS CHARACTERIZATION
·
2025
·
IF 5.5
Dang Xu,Pengqi Chen,Kaichao Fu,Changcheng Sang,Ruizhi Chen,Tao Hong,Jigui Cheng,Kai Xu
The inherent metallurgical incompatibility between dissimilar metals such as tungsten (W) and copper (Cu) engenders weak chemical bonding, substantially constraining the attainment of high strength. This constitutes a critical limitation for nuclear fusion applications demanding robust interfacial integrity. To address these limitations, this study introduces a dual interface reinforcement strategy employing a CrCoNi medium entropy alloy (MEA) interlayer and achieving diffusion bonding of oxide diffusion-strengthened tungsten (ODS-W) and Cu through spark plasma sintering (SPS) technology. At the optimized bonding temperature of 1000 °C, the joint achieves a maximum tensile strength of 256.7 ± 8.2 MPa, corresponding to a 171 % enhancement over direct bonding (DB) joint (94.6 ± 5.1 MPa), accompanied by a fracture mode transition from brittle to ductile failure. Multi-scaled microstructure and interface element diffusion behavior analyses reveal that reactive diffusion at the W/MEA interface facilitates the formation of a solution-strengthened matrix associated with an amorphous diffusion layer. Whereas mutual diffusion at the Cu/MEA interface induces multiple phase structures, resulting concurrently in solid solution strengthening and precipitation strengthening, thereby reinforcing the interface bonding. This dual interface reinforcement methodology establishes an effective design strategy for enhancing mechanical properties in immiscible metal systems.
研究领域:
材料科学
·
冶金学
·
核工程
·
机械工程
·
连接技术
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产品关联
DOI
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Xianmin Gong,Yi He,Liping Yan,Huilian Zhou,Yiling He,Kaijun Wei,Quangang Chen,Shijun Xu
In this study, vanadium carbide (VC) was used as the raw material to synthesize PDA-functionalized VC (P-VC). VC and P-VC were added as nanoreinforced materials to the Ni–W–B coating. The effects of the two nanomaterials on the morphology, wear resistance, and corrosion resistance of the Ni–W–B coatings were investigated and compared. The experimental results show that the surface of the Ni–W–B/P-VC coating is denser and more uniform than that of the Ni–W–B and Ni–W–B/VC coatings, and there are no obvious defects on the surface. According to the hardness test, the Ni–W–B/P-VC coating reaches the highest microhardness of 887.1 HV. According to the friction and wear tests, the Ni–W–B/P-VC coating has the shallowest scratches, the lowest average friction coefficient (COF = 0.274), and the lowest wear rate (9.578 × 10–8 mm2/N). The corrosion resistance is the best, the corrosion rate is 0.0456 mm/y, and the impedance value Rt reaches 14,501 Ω·cm2.
研究领域:
材料科学
·
表面工程
·
涂层技术
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2022
·
IF 10.319
Zhi Zhao,Fawei Tang,Chao Hou,Xintao Huang,Xiaoyan Song
Characterizing immiscible metallic composites with electron microscopy and X-ray spectroscopy is the classic way of obtaining their structural and physical details. Nevertheless, such a combination lacks ability to tell the interfacial interactions at grain boundaries. Here we demonstrate a novel strategy to uncover the mystery of interfacial interactions in such systems by spectroscopic microscopy. The morphological and spectral data of samples were simultaneously recorded and analyzed, which reveals critical information regarding interfacial electronic modes. Taking W-Cu as a model, we experimentally quantified its connectivity and unambiguously identified conditional bonding between W and Cu. Further, we chemically reconstructed the specific W-Cu boundary that possessed the strongest interactions and investigated its atomic structure. The mechanism of W-Cu bonding was proposed and verified by first-principle calculations. The above methodology holds great promise to serve as a universal approach in achieving in-depth understanding of immiscible composites.
研究领域:
材料科学
·
冶金学
·
显微镜技术
·
光谱学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Lirui Ren,Bin Huang,Wensheng Fang,Daqi Zhang,Hongyan Cheng,Zhaoxin Song,Dongdong Yan,Yuan Li,Qiuxia Wang,Zhiqiang Zhou,Aocheng Cao
Dimethyl disulfide (DMDS), a promising alternative fumigant, has been highly desirable for excellent management of soil pests and diseases. However, high volatility and moderate toxicity of this sulfide limit its application. To address these issues, a novel controlled release formulation of DMDS was proposed employing multiple emulsions and polyurea microcapsules (DMDS@MEs-MCs). The successful combination of the two technologies was revealed by confocal laser scanning microscopy, scanning electron microscopy, thermogravimetric analysis, and Fourier transform infrared. According to the multiple encapsulation structure, the encapsulation efficiency decreased by only 3.13% after thermal storage, compared with a 15.21% decrease of microcapsules made with only a monolayer film. DMDS@MEs-MCs could effectively control the release of active ingredient, which increased applicator and environmental safety during application. Moreover, it could be facilely used by spraying and drip irrigation instead of a special fumigation device. The innovative formulation exhibited better control efficacy on soil pathogens (Fusarium spp. and Phytophthora spp.) and root-knot nematodes (Meloidogyne spp.) than DMDS technical concentration (DMDS TC). In addition, it did not inhibit seed germination after 10 days when the plastic film was removed from the fumigated soil. This method appears to be of broad interest for the development of safe and handy fumigant application.
研究领域:
农业科学
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化学工程
·
植物病理学
·
环境科学
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DOI
PubMed
高影响因子
CATALYSIS LETTERS
·
2026
·Vol. 156
·期 3
·65
·
IF 2.5
Hu Yanan,Yang Dawei,Li Qiaoling,Yu Chengcheng
The insufficient catalytic efficiency of non-noble metal materials in the alkaline hydrogen evolution reaction (HER) remains a critical challenge limiting their practical application. Herein, a W-modified NiSe 2 -based catalyst (Ni-W-Se/NF) was in situ fabricated on nickel foam through a simple potentiostatic electrodeposition strategy. The incorporation of W effectively modulates the microstructure of NiSe 2 -based catalysts, resulting in a significantly enlarged electrochemical active surface area for Ni-W-Se/NF. Benefiting from the synergistic effects of W-induced electronic modulation and morphology optimization, the Ni–W–Se/NF electrode exhibits enhanced HER performance in 1 M KOH, delivering a low overpotential of 64 mV at − 10 mA cm −2 . Moreover, the catalyst demonstrates good electrochemical durability, maintaining stable activity during continuous operation for 50 h. Overall, these findings highlight the potential of this catalyst as an economically viable cathode for alkaline water electrolysis. Graphical
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DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Dong Yan,Xuetao Cheng,Xiaoxiao Dong,Han Wang,Xingchen Chang,Chenghui Xia,Yongcheng Jin,Chun-Chao Hou
Electrolysis of seawater driven by renewable energy holds great promise for sustainable hydrogen production. However, both catalyst corrosion caused by competitive Cl − adsorption and sluggish reaction kinetics are major challenges in seawater electrolysis. Here, inspired by the concept of hard and soft acids and bases (HSAB), a unique interfacial W-O-Co electron bridge is constructed on the catalyst surface to achieve the electronic coupling of hard-acid W site and borderline-acid Co site via the oxygen bridge, which demonstrates exceptional performance for both the hydrogen evolution reaction (HER) and the oxygen evolution reaction (OER) in alkaline water and seawater, as well as high anti-corrosion stability. Remarkably, WO 3 /CoP electrode requires low overpotentials of merely 154 mV (alkaline freshwater) and 189 mV (alkaline seawater) for HER, and 334 mV (alkaline freshwater) and 343 mV (alkaline seawater) for OER to achieve 100 mA cm −2 , respectively. When deployed our bifunctional catalyst as both anode and cathode in an alkaline anion-exchange membrane seawater electrolyzer, the system achieves 1 A cm −2 at a low cell voltage of 1.80 V and maintains stable electrolysis for over 250 h at 100 mA cm −2 . Theoretical and experimental investigations reveal that the hard-acid W site of the electronic W-O-Co bonded bridge prefers adsorption of hard-base OH - rather than soft-base Cl - , thereby mitigating Cl - interference and suppressing chloride corrosion. Simultaneously such interfacial W-O-Co bridging significantly accelerates charge transfer from Co site to W site, thereby regulating the electronic structures of catalysts and optimizing the sorption behaviors of reaction intermediates. This work provides a feasible anti-corrosion engineering strategy to design efficient and robust electrocatalysts for practical seawater electrolysis.
研究领域:
电化学
·
材料科学
·
氢能
·
催化
·
可再生能源
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产品关联
DOI
高影响因子
Acta Biomaterialia
·
2024
·
IF 9.4
Qingrong Li,Cong Zhang,Mengmei Zhu,Jie shan,Haisheng Qian,Yan Ma,Xianwen Wang
Inflammatory bowel disease (IBD) may arise due to disruption of mucosal barriers as a result of dysregulation of the intestinal flora and excessive oxidative stress. The creation of nanomaterials with only microbiota-regulating effects often leads to inadequate therapeutic outcomes caused by the disruption of a healthy microbial balance and the emergence of tissue harm caused by excessive oxidative stress. This report describes the multifunctional activity of ultrasmall W-GA nanodots, which can precisely regulate the intestinal microbiome by inhibiting the abnormal expansion of Enterobacteriaceae during colitis and alleviating the damage caused by oxidative stress to the reconstructive microflora, ultimately restoring intestinal barrier function. W-GA nanodots have been synthesized through a simple coordination reaction and can be dispersed in various solvents in vitro , demonstrating favorable safety profiles in cells, significant clearance of reactive oxygen and nitrogen species (RONS), and increased cell survival in models of oxidative stress induced by hydrogen peroxide (H 2 O 2 ). Through oral or intravenous administration, the W-GA nanodots were shown to be highly safe when tested in vivo , and they effectively reduced colon damage in mice with DSS-induced colitis by restoring the integrity of the intestinal barrier. W-GA nanodots have enabled the integration of microflora reprogramming and RONS clearance, creating a potent therapeutic strategy for treating gut inflammation. Consequently, the development of W-GA nanodots represents a promising strategy for enhancing the formation and preservation of the intestinal barrier to treat IBDs by suppressing the growth of Enterobacteriaceae , a type of facultative anaerobic bacterium, and facilitating the effective removal of RONS. Ultimately, this leads to the restoration of the intestinal barrier's functionality. Statement of Significance An increasing number of nanoparticles are under development for treating inflammatory bowel disease. Although they can alleviate inflammation symptoms by regulating reactive oxygen and nitrogen species (RONS) and microbiota, their understanding of the mechanism behind microbiota regulation is limited. This study synthesized W-GA nanodots using a straightforward one-pot synthesis method. Simple synthesis holds significant promise for clinical applications, as it encompasses multiple nanoenzyme functions and also exhibits Enterobacteriaceae inhibitory properties.Thus, it contributes to ameliorating the current medical landscape of inflammatory bowel disease.
研究领域:
纳米技术
·
胃肠病学
·
药学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2020
·Vol. 27
·期 13
·7591-7605
·
IF 4.21
Wang Haiyong,Hu Xiaohong,Liu Siwei,Cai Chiliu,Zhu Changhui,Xin Haosheng,Xiu Zhongxun,Wang Chenguang,Liu Qiying,Zhang Qi,Zhang Xinghua,Ma Longlong
The bi-functional Ni–W@C catalysts were prepared by one-pot reduction–carbonization method and used in hydrogenolysis of cellulose as well as raw lignocellulosic biomass to chemicals. The catalytic performance for cellulose conversion showed that it was more favorable for ethylene glycol (EG) production, obtaining the highest EG yield 60.1% over the Ni–W@C 700 catalyst. The Ni–W@C bimetallic catalysts are systematically characterized with BET, XRD, Raman, XPS, TEM techniques and experiments to probe the active catalytic sites of the catalysts. The effects of calcination temperature of Ni–W catalysts, reaction time, temperature and H 2 pressure on cellulose hydrogenolysis were investigated in detail. The Ni particles could lead to produce more W 5+ active sites, which promotes the glucose retro-aldol condensation to break the target C–C bonds. Metallic Ni catalyzed C=O hydrogenation and C–C hydrogenolysis, which could also avoid the coke formation. The EG selectivity was dependent on the synergy of WO x and Ni metal sites. In addition, this synergistic effect between the metal and WO x could promote lignin component degradation in direct conversion of untreated raw lignocellulosic biomass, obtaining the propyl monophenolics including guaiacylpropane, syringylpropane and p-n-propylphenol with a total yield of 17.3 wt% besides EG.
研究领域:
化学工程
·
催化
·
生物化工
·
材料科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）