Journal of Ovarian Research
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2020
·Vol. 13
·期 1
·57-57
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IF 2.989
Gengxiang Wu,Xue Hu,Jinli Ding,Jing Yang
Background Previous studies have shown that chronic inflammation and oxidative stress may play an important role in the pathophysiology of polycystic ovary syndrome (PCOS), and glutamine (Gln) have showed the anti-inflammatory and antioxidant properties. So the aim of this study is to investigate the effect of glutamine supplementation on PCOS rats. Methods Female Sprague-Dawley rats were randomly assigned into four groups (n = 10 /group), control group, PCOS group, PCOS+ 0.5 g/kg Gln group and PCOS+ 1.0 g/kg Gln group. All the PCOS rats were administrated with 6 mg/100 g dehydroepiandrosterone (DHEA) for 20 consecutive days, all the PCOS+Gln groups were intraperitoneal injected glutamine twice in the next morning after the last DHEA injection. All the samples were collected 12 h after the last administration. Ovarian histological examinations were analyzed and the concentration of serum hormone, inflammatory and oxidative stress factors were measured. Results There was no obvious ovarian histological change among the PCOS group and PCOS+Gln groups. All the detected inflammation factors [C-reactive protein, interleukin (IL)-6, IL-18, tumor necrosis factor] showed significantly higher in all the PCOS groups compared to the control group (P < 0.01), and were significantly decreased with the supplementation of 0.5 g/kg glutamine (P < 0.01). Concentrations of superoxide dismutase were significantly lower in all the PCOS groups (P < 0.01) compared to the control group, and increased significantly with the supplementation of 0.5 g/kg glutamine (P < 0.01). Serum concentrations of malondialdehyde, nitric oxide synthase and nitric oxide were significantly higher in PCOS group (P < 0.01) compared with the control group, and significantly decreased to the comparative levels of control group with supplementation of 0.5 g/kg glutamine (P < 0.01). Conclusion There is low-grade inflammation and oxidative stress in DHEA-induced PCOS rats. The supplementation of 0.5 g/kg glutamine could effectively ameliorate the inflammation and oxidative stress conditions of PCOS.
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International Journal of Oral Science
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2020
·Vol. 12
·期 1
·1-10
·
IF 3.047
Zhang Ruilin,Li Junhui,Li Gongchen,Jin Fujun,Wang Zuolin,Yue Rui,Wang Yibin,Wang Xiaogang,Sun Yao
Activation of osteoclasts during orthodontic tooth treatment is a prerequisite for alveolar bone resorption and tooth movement. However, the key regulatory molecules involved in osteoclastogenesis during this process remain unclear. Long noncoding RNAs (lncRNAs) are a newly identified class of functional RNAs that regulate cellular processes, such as gene expression and translation regulation. Recently, lncRNAs have been reported to be involved in osteogenesis and bone formation. However, as the most abundant noncoding RNAs in vivo, the potential regulatory role of lncRNAs in osteoclast formation and bone resorption urgently needs to be clarified. We recently found that the lncRNA Nron (long noncoding RNA repressor of the nuclear factor of activated T cells) is highly expressed in osteoclast precursors. Nron is downregulated during osteoclastogenesis and bone ageing. To further determine whether Nron regulates osteoclast activity during orthodontic treatment, osteoclastic Nron transgenic (Nron cTG) and osteoclastic knockout (Nron CKO) mouse models were generated. When Nron was overexpressed, the orthodontic tooth movement rate was reduced. In addition, the number of osteoclasts decreased, and the activity of osteoclasts was inhibited. Mechanistically, Nron controlled the maturation of osteoclasts by regulating NFATc1 nuclear translocation. In contrast, by deleting Nron specifically in osteoclasts, tooth movement speed increased in Nron CKO mic e . These results indicate that lncRNAs could be potential targets to regulate osteoclastogenesis and orthodontic tooth movement speed in the clinic in the future.
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JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
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2020
·Vol. 35
·期 2
·441-448
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IF 0.64
Xiong Yan,Zhang Yucheng,Liu Wei,Liu Yang,Tan Junjun
A citrate-assisted hydrothermal method was utilized for the preparation of Sr-substituted hydroxyapatite (HA) nanoparticles. The influences of Sr-substituting degree on the phase identifications, microstructures and colloidal stability of the resultant products were studied. The experimental results show that the crystalline structures and morphologies of final resultants are significantly changed by controlling the Sr-substituting degree. As the Sr-substituting degree increases, the colloidal stability of samples first increases and then decreases rapidly; the morphology of the product first changes from nanorods to short nanorods rod and then becomes nanowires. Uniform HA hexagonal nanorods with high aspect ratio (>4.0) and excellent aqueous colloidal stability were prepared by 6 h hydrothermal reaction at 180 °C without Sr substitution. The dispersion underwent the phase transition from isotropic to liquid-crystalline state upon the increasing concentration of 25wt% and the complete liquid-crystalline phase was achieved when at the concentration above 31wt%. These novel findings provide new insights into the role of Sr substitution on both the citrate-assisted hydroxyapatite crystallization and tailoring of colloidal stability. Moreover, HA liquid crystal behavior was successfully observed, which lays a foundation for the fabrication of macroscopically assembled hydroxyapatite-based biomimetic materials for biomedical applications.
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SN Applied Sciences
·
2020
·Vol. 2
·期 5
·1-10
·
IF 0
Putra Ageng Trisna Surya Pradana
A spinel structure of zinc aluminate (ZnAl 2 O 4 ) particles provides a prospective material for photocatalytic applications. In this work, zinc aluminate spinel was prepared by an anion-exchange method derived from layered double hydroxides (LDHs) followed by thermal treatment. The mechanism, photoactivity, and effects of both anion substitute and temperature have been investigated. The chemical composition, morphologies, phase structures, porous structures and photocatalytic properties of samples were analyzed using thermogravimetric analysis, scanning electron microscopy, energy-dispersive X-ray spectroscopy, powder X-ray diffraction, gas sorption analysis, and ultraviolet–visible spectroscopy in detail. The results of mesoporous α -ZnAl 2 O 4 indicate that average crystallite size, total pore volume, and BET surface area obtain 9.3 nm, 0.337 cm 3 /g, and 206.13 m 2 /g, respectively. Moreover, zinc aluminate spinel shows well phase after heating at 700 °C and LDHs structures were completely collapsed. The photocatalytic performances of α -ZnAl 2 O 4 have been applied in p -nitrophenol reduction under visible light irradiation and required time at least 9 min. Finally, the new improved method constructs an excellent material for pretreatment of liquid pollutants containing high-level concentration at rapid treatment time.
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APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
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2020
·Vol. 126
·期 3
·1-10
·
IF 1.81
Ji Changyan,Li Lingzhi,Huang Zhi,Wen Jin,Huang Ting-Hong,Tian Xiuying,Wu Tengyan,He Hengping,Zhang Lei,Peng Yangxi
Eu 3+ -doped germanate based red emitting phosphors SrGe 4 O 9 : x Eu 3+ (0 ≤ x ≤ 0.5 mol%) were prepared by high-temperature solid-state procedure. Moreover, the Density Functional Theory (DFT) calculation, X-ray diffraction (XRD) Rietveld refinement, scanning electron microscopy (SEM), and photoluminescence (PL) measurement were discussed in detail to fully investigate the crystal structure and PL properties of SrGe 4 O 9 : x Eu 3+ . Furthermore, the Judd–Ofelt ( J – O ) analysis demonstrated that the Eu 3+ ions in the SrGe 4 O 9 host possessed lower sites symmetry. In addition, the phosphor SrGe 4 O 9 : 0.35%Eu 3+ displayed superior thermal stability with PL intensity at 423 K is around 90% of its initial value at 298 K. As a result, the white light emitting diodes (WLED) device based on SrGe 4 O 9 : 0.35%Eu 3+ achieved an expected result of a correlated color temperature (CCT) of 4573 K and a color rendering index (CRI) of 80.8 under a voltage of 3 V and a driven current of 20 mA.
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JOURNAL OF SOLUTION CHEMISTRY
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2020
·Vol. 49
·期 2
·145-165
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IF 1.273
Yang Xuzhao,Wang Jun,Fang Yun
Asymmetrical ammonium-based gemini ionic liquids, 1-trimethylammonium-3-(1-methylpiperidinium)propane dibis[(trifluoromethyl)sulfonyl]imide ([N 111 C 3 MPip][NTf 2 ] 2 ) and 1-trimethylammonium-3-(4-methylmorpholinium)propane dibis[(trifluoromethyl)sulfonyl]imide ([N 111 C 3 MMor][NTf 2 ] 2 ), were synthesized and structurally characterized by 1 H NMR, 13 C NMR, and MS. The melting temperatures and associated enthalpies and entropies of fusion of these gemini ionic liquids have been determined through differential scanning calorimetry (DSC). Thermal stabilities of [N 111 C 3 MPip][NTf 2 ] 2 and [N 111 C 3 MMor][NTf 2 ] 2 have been investigated by thermogravimetric analysis technology under pure nitrogen atmosphere. The solubility data of [N 111 C 3 MPip][NTf 2 ] 2 and [N 111 C 3 MMor][NTf 2 ] 2 in water, ethanol, benzyl alcohol, 2-phenylethanol and n -heptane were determined by a synthetic method using a laser monitoring observation technique in the temperature range 298.15–333.15 K under atmospheric pressure. The solubility in all pure solvents increased with the increasing temperature and the greatest solubilities of both gemini ionic liquids were observed in benzyl alcohol. The modified Apelblat, Buchowski–Ksiazaczak λh and NRTL models were employed to correlate the experimental solubility data. The calculated results show good agreement with the experimental data and modified Apelblat and λh equations are more accurate than the NRTL model. The standard state enthalpy, entropy, and Gibbs energy of dissolution of the GILs in the studied solvents were evaluated through the van′t Hoff equation using the experimental solubility data. The excess enthalpies of the solutions were also determined by the λh model. The dissolution behavior can serve for the synthesis and purification process of GILs.
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NATURE MATERIALS
·
2020
·Vol. 19
·期 5
·552-558
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IF 38.663
Bi Sheng,Banda Harish,Chen Ming,Niu Liang,Chen Mingyu,Wu Taizheng,Wang Jiasheng,Wang Runxi,Feng Jiamao,Chen Tianyang,Dincă Mircea,Kornyshev Alexei A.,Feng Guang
We performed constant-potential molecular dynamics simulations to analyse the double-layer structure and capacitive performance of supercapacitors composed of conductive metal–organic framework (MOF) electrodes and ionic liquids. The molecular modelling clarifies how ions transport and reside inside polarized porous MOFs, and then predicts the corresponding potential-dependent capacitance in characteristic shapes. The transmission line model was adopted to characterize the charging dynamics, which further allowed evaluation of the capacitive performance of this class of supercapacitors at the macroscale from the simulation-obtained data at the nanoscale. These ‘computational microscopy’ results were supported by macroscopic electrochemical measurements. Such a combined nanoscale-to-macroscale investigation demonstrates the potential of MOF supercapacitors for achieving unprecedentedly high volumetric energy and power densities. It gives molecular insights into preferred structures of MOFs for accomplishing consistent performance with optimal energy–power balance, providing a blueprint for future characterization and design of these new supercapacitor systems.
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CATALYSIS SURVEYS FROM ASIA
·
2020
·Vol. 24
·期 2
·115-122
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IF 2.194
Gao Meixiang,Jiang Haoxi,Zhang Minhua
This paper has systematically investigated the structures and properties of the ZrO 2 , Nano-SiO 2 and their composition. The catalysts were prepared by impregnation, characterized by N 2 adsorption–desorption, TEM, XRD, Raman, temperature-programmed desorption of NH 3 and CO 2 , FTIR spectroscopy of adsorbed pyridine and CO 2 , and UV–vis spectra. Compared with dry-mixed samples, these catalysts have larger average pore diameter, enabling ZrO 2 to be dispersed more uniformly on the surface of Nano-SiO 2 . With the Zr–O–Si bonds, ZrO 2 could interact intensely with Nano-SiO 2 . The catalyst prepared shows the best performance, with the selectivity of 93.18% and conversion of 58.52%. The preparation methods have a significant influence on the interaction between ZrO 2 and Nano-SiO 2, which then affects the acid–basic properties. This paper finds that weak acid–basic sites with moderate-intensity are more suitable for ethanol conversion to BD, with the amount of acid and basic sites as close as possible.
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Science China-Technological Sciences
·
2020
·Vol. 63
·期 8
·1470-1477
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IF 2.302
Gong LiuTing,Xu Miao,Ma RenPing,Han YingPing,Xu HongBo,Shi Gang
Transition metal oxide is a promising candidate for future supercapacitors due to its pronounced electrical properties and low cost. Unfortunately, the poor cycle stability and low capacitance due to the small lattice spacing and strong volume expansion in dense transition metal oxide impede its practical applications seriously. Herein, a nanoporous electrode of metal oxide has been prepared via the solvothermal and subsequent calcination process of MOF-74 (MOF=metal-organic framework), which shows outstanding cycle reversibility, excellent capacitance. Because of large surface areas with a nanoporous structure which is beneficial to the ion transport and relief to volume expansion. Three samples with different divalent metals (MOF-74-Ni, MOF-74-NiCo 2 and MOF-74-Co) were prepared by hydrothermal method. After a facile annealing process, the NiO, NiCo 2 O 4 and Co 3 O 4 with the large surface area and porous structure were easily obtained and further the electrochemical properties were investigated. As a result, the NiCo 2 O 4 electrode exhibits obviously high specific capacity (684 F/g) and excellent cycling stability (86% retention after 3000 cycles) compared with the monometallic oxides.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2020
·Vol. 31
·期 16
·13503-13510
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IF 2.22
Guo Xiaogang,Wang Jing,Liang Taotao,Yuan Binfang,Sun Qi
It is still a bottleneck to design anti-wetting homogeneous metal films or coatings with great stability via by a high-efficiency and low-cost technique with applications in fields of battery, sensors, and electronics, etc. This paper proposed an environment-friendly ultra-low-voltage electrophoretic deposition (EPD) with facile modification post-processing method to fabricate a novel extremely water-repellent functional nano-Al films with evenly loose net-like structures and high purity. The optimized stable suspension consists of water–ethanol with trace nitric acid and polyethyleneimine. Product with an ultra-high contact angle of ~ 171° and extreme low sliding angle of < 1° showed extremely anti-wetting properties, and outstanding water-repellent stability or long lifespan (> 3 years) with great potential applications. These results provide a novel approach with low-cost and less energy consumption for preparing other functional ant-wetting metal coatings with wide potential applications.
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Nano-Micro Letters
·
2020
·Vol. 12
·期 1
·1-19
·
IF 12.264
Peng Xin,Chen Kun,Liu Wanhua,Cao Xiongfeng,Wang Mengru,Tao Jun,Tian Ying,Bao Lei,Lu Guangming,Teng Zhaogang
Soft mesoporous organosilica nanoplatforms modified with hyaluronic acid and cyanine 5.5 are constructed.
Therapeutic efficacy of the soft nanoplatforms on tumor is higher both in vitro and in vivo after loading photosensitizer chlorin e6 compared to that of stiff counterparts.
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 6
·1-8
·
IF 6.232
Wang Xiuli,Cheng Zhili,Zhou Yun,Tammina Sai Kumar,Yang Yaling
A fluorescence method is described for the determination of hydroquinone based on the double carbon dot system as peroxide mimic enzymes and fluorescent probes. Deep eutectic solvent (DES)–based fluorescent carbon dots (N/Cl-CDs) and copper-doped carbon dots (N/Cu-CDs) were prepared by the hydrothermal method. Both carbon dots were characterized with transmission electron microscopy (TEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), ultraviolet-visible (UV-Vis) spectroscopy, X-ray photoelectron spectrometry (XPS), Fourier transform infrared (FT-IR) spectroscopy, and fluorescence spectroscopy. N/Cl-CDs displayed intrinsic peroxidase-like activity and were able to catalyze the oxidation of hydroquinone (H 2 Q) to p-benzoquinone (BQ) along with an intermediate. The intermediate (BQ) did quench the N/Cu-CD photoluminescence (PL) at 450 nm using an excitation wavelength of 347 nm. Based on the results, a fluorescent platform is proposed for the determination of hydroquinone with a promising determination limit of 0.04 μM (linear range, 1.0–75 μM). The recoveries of spiked water samples were in the range 89.5–105.1%, with relative standard deviations (RSDs) of 1.5–2.9%. This method was applied to determination of H 2 Q in environmental water samples.
A fluorescence method was established for the determination of hydroquinone based on the double carbon dot system as peroxide-mimic enzymes and fluorescent probes. Chlorine-doped carbon dots (N/Cl-CDs) derived from deep eutectic solvent (DES) displayed intrinsic peroxidase-like activity, and were able to catalyze the oxidation of hydroquinone (H2Q) to p-benzoquinone (BQ) along with an intermediate. The intermediate (BQ) did quench the N/Cu-CD photoluminescence (PL). This method was applied to H2Q in environmental water samples.
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