POLYMER JOURNAL
·
2019
·Vol. 51
·期 11
·1211-1222
·
IF 2.639
Liu Guanghua,Lin Guanquan,Tan Mingyi,Zhou Hongjun,Chen Huayao,Xu Hua,Zhou Xinhua
To improve the utilization of pesticides and reduce the amount of pesticides used, sustained-release nanoparticles were prepared. Soybean protein isolate (SPI) and carboxymethyl cellulose (CMC) were modified to obtain hydrazine-modified SPI and aldehyde-modified CMC, respectively, and SPI-CMC was prepared by the condensation of hydrazine and aldehyde groups, forming a hydrazone bond. SPI-CMC was heated and loaded with avermectin (AVM) to obtain AVM/SPI-CMC. The encapsulation efficiency property, anti-ultraviolet property, sustained-release characteristics, pH responsiveness, and toxicological profiles were studied. The particles in the formulation were spherical-like, with sizes ranging between 150 and 250 nm. The encapsulation efficiency increased with the addition of SPI, which reached 44.49% when SPI was added in a mass ratio of m SPI-HYD : m CMC-ALD = 2:1. The percentage of remaining AVM in AVM/SPI-CMC was 31.47% higher than that in the AVM solution after UV irradiation for 43 h. Moreover, the nanoparticles were responsive to pH. SPI-CMC had no significant effect on the insecticidal toxicity of AVM. Environmental friendly SPI-CMC could protect and release pesticides continuously, which could improve the efficiency of pesticides.
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JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
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2019
·Vol. 34
·期 3
·604-613
·
IF 0.605
Ma Baoguo,Mei Junpeng,Tan Hongbo,Li Hainan,Liu Xiaohai,Jiang Wenbin,Zhang Ting
The influences of nano silica (NS) on the hydration and microstructure development of steam cured cement high volume fly ash (40 wt%, CHVFA) system were investigated. The compressive strength of mortars was tested with different NS dosage from 0 to 4%. Results show that the compressive strength is dramatically improved with the increase of NS content up to 3%, and decreases with further increase of NS content ( e g , at 4%). Then X-ray diffraction (XRD), differential scanning calorimetry-thermogravimetry (DSCTG), scanning electron microscope (SEM), energy disperse spectroscopy (EDS), mercury intrusion porosimeter (MIP) and nuclear magnetic resonance (NMR) were used to analyze the mechanism. The results reveal that the addition of NS accelerates the hydration of cement and fly ash, decreases the porosity and the content of calcium hydroxide (CH) and increases the polymerization degree of C-S-H thus enhancing the compressive strength of mortars. The interfacial transition zone (ITZ) of CHVFA mortars is also significantly improved by the addition of NS, embodying in the decrease of Ca/Si ratio and CH enrichment of ITZ.
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MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 7
·1-9
·
IF 5.705
Wang Jiasheng,Hui Ni
A non-fouling electrochemical immunosensor is described for determination of the tumor biomarker carcinoembryonic antigen (CEA). It is based on the use of composite wires made by chemical grafting of hyaluronic acid onto polyaniline nanowires. The modified nanowires possess excellent antifouling property both in single protein solutions and in dilute serum samples. The current of immunoelectrode exhibits a linear response in the 0.01 pg mL −1 to 10,000 pg mL −1 CEA concentration range and 0.0075 pg mL −1 detection limit. This work demonstrates that coating an electrode with hyaluronic acid can largely reduce unspecific adsorption of proteins on the electrode surface.
Schematic of a nonfouling electrochemical immunosensor for the carcinoembryonic antigen. It is based on novel composite wires made through the chemical grafting of easily available hyaluronic acid (HA) onto polyaniline (PANI) nanowires. The HA/PANI demonstrated excellent antifouling property both in single protein solutions and human serum samples.
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高影响因子
Scientific Reports
·
2018
·Vol. 8
·期 1
·1-10
·
IF 4.122
Yang Aili,Zhu Yukuan,Huang C. P.
To overcome the limits of low adsorption capacity and the separation difficulty of solid from liquid phase for graphene oxide (GO), a novel nanocomposite graphene oxide-manganese oxide (GOMO) was facilely fabricated under ultrasonic radiation. The structures and micro-morphology of the products were characterized by fourier transform infrared (FT-IR) spectroscopy, raman shift spectroscopy, X-ray diffraction (XRD) pattern and scanning electron microscopy (SEM). The effect of solution pH, adsorbent dose, contact time, initial uranium concentration, ionic strength and temperature on uranium removal efficiency was studied by batch adsorption experiments. The product GOMO was used to examine the feasibility of the removal of high salt content in uranium-containing wastewater. The adsorption results were fitted using the Langmuir and Freundlich isotherm models. The kinetic parameters in the adsorption process were measured and fitted. Five adsorption/desorption cycles were performed using 3 M HNO 3 as the regenerant in order to evaluate the reuse of GOMO.
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高影响因子
NEUROCHEMICAL RESEARCH
·
2018
·Vol. 43
·期 7
·1439-1453
·
IF 2.772
Jia Jingjing,Zhang Ting,Chi Jieshan,Liu Xiaoma,Sun Jingjing,Xie Qizhi,Peng Sijia,Li Changyan,Yi Li
CeO 2 nanoparticles (nanoceria) have been used in many studies as a powerful free radical scavenger, and LXW7, a small-molecule peptide, can specifically target the integrin αvβ3, whose neuroprotective effects have also been demonstrated. The objective of this study is to observe the neuroprotective effect and potential mechanism of CeO 2 @PAA-LXW7, a new compound that couples CeO 2 @PAA (nanoceria modified with the functional group of polyacrylic acid) with LXW7 via a series of chemical reactions, in H 2 O 2 -induced NGF-differentiated PC12 cells. We examined the effects of LXW7, CeO 2 @PAA, and CeO 2 @PAA-LXW7 on the viability of primary hippocampal neurons and found that there was no significant difference under control conditions, but increased cellular viability was observed in the case of H 2 O 2 -induced injury. We used H 2 O 2 -induced NGF-differentiated PC12 cells as the classical injury model to investigate the neuroprotective effect of CeO 2 @PAA-LXW7. In this study, LXW7, CeO 2 @PAA, and CeO 2 @PAA-LXW7 inhibit H 2 O 2 -induced oxidative stress by reducing the production of reactive oxygen species (ROS) and regulating Bax/Bcl-2, cleaved caspase-3 and mitochondrial cytochrome C (cyto C) in the apoptotic signaling pathways. We found that the levels of phosphorylation of focal adhesion kinase (FAK) and of signal transducer and activator of transcription 3 (STAT3) increased significantly in H 2 O 2 -induced NGF-differentiated PC12 cells, whereas LXW7, CeO 2 @PAA, and CeO 2 @PAA-LXW7 suppressed the increase to different degrees. Among the abovementioned changes, the inhibitory effect of CeO 2 @PAA-LXW7 on H 2 O 2 -induced changes, including the increases in the levels of p-FAK and p-STAT3, is more obvious than that of LXW7 or CeO 2 @PAA alone. In summary, these results suggest that integrin signaling participates in the regulation of apoptosis via the regulation of ROS and of the apoptosis pathway in H 2 O 2 -induced NGF-differentiated PC12 cells. LXW7, CeO 2 @PAA, and CeO 2 @PAA-LXW7 can play neuroprotective roles by counteracting the oxidative stress and apoptosis induced by H 2 O 2 in NGF-differentiated PC12 cells. CeO 2 @PAA-LXW7 exerting a more powerful synergistic effect via the conjunction of LXW7 and CeO 2 @PAA.
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高影响因子
JOURNAL OF POLYMER RESEARCH
·
2018
·Vol. 25
·期 7
·1-12
·
IF 1.434
Hu Yan,Zhang Shangwen,Han Dandan,Ding Zongxian,Zeng Suying,Xiao Xincai
We prepared a hydroxypropyl methyl cellulose-sodium alginate (HPMC-SA) composite hydrogel with a membrane covering the semi-interpenetrating network based on a semi-synthetic polymer hydroxypropyl methyl cellulose (HPMC) and a natural polymer sodium alginate (SA) by Ca 2+ crosslinking and polyelectrolyte complexation with chitosan (CS) covering the hydrogel surface. The physiochemical properties of HPMC-SA hydrogels were evaluated by scanning electron microscopy, infrared spectrum, X-ray diffraction, and thermogravimetric analysis. The swelling ratio of the HPMC-SA composite hydrogel in simulated gastrointestinal fluid was measured. The drug release behavior of the HPMC-SA composite hydrogel for macro-molecular and small-molecule drugs was evaluated by using bovine serum albumin, metformin hydrochloride, and indomethacin as model drugs. The results showed that the HPMC-SA hydrogel had good water absorption and degradability, an increased swelling ratio of 55, and a prolonged time for maximum swelling degree of 50 h. Moreover, the hydrogel exhibited higher drug-loading capacity and improvements in the sustained release of bio-macromolecules, demonstrating its potential as a drug carrier for biomedical applications.
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RESEARCH ON CHEMICAL INTERMEDIATES
·
2018
·Vol. 44
·期 9
·5439-5453
·
IF 1.674
Huang Feng,Li Wenzhi,Zhang Tingwei,Li Dawei,Liu Qiyu,Zhu Xifeng,Ma Longlong
A carbonaceous solid acid catalyst with high strong-acid density was synthesized by facile functionalization of a biomass-derived mesoporous carbon with benzenesulfonic acid. The catalyst was characterized by using Fourier transform infrared spectroscopy, elemental analysis, X-ray photoelectron spectroscopy, transmission electron microscopy, and N 2 adsorption–desorption. The carbonaceous solid catalyst containing Brønsted acid sites was used for the production of 5-hydroxymethylfurfural (HMF) from hexoses such as fructose, glucose, and cellulose in γ-valerolactone (GVL)-H 2 O mixture. By reaction at 130 °C for 20 min using fructose as a feedstock, an HMF yield 78.1% was achieved. The catalytic performance of the catalyst in conversion of fructose into HMF hardly changed over seven cycles, demonstrating that the catalyst had excellent recyclability. The yields of HMF derived from glucose and cellulose reached 33.2 and 22.5%, respectively, whereas those of total furans were 42.1 and 33.7%, respectively. The proposed reaction system was promising in transforming biomass-based carbohydrates into fine chemicals, given the use of green functionalization methods, the utilization of sustainable biomass-derived carbon precursor and solvents, catalyst with high acid density, and the availability of high HMF yield.
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高影响因子
INTERNATIONAL JOURNAL OF THERMOPHYSICS
·
2018
·Vol. 39
·期 5
·1-11
·
IF 0.829
Fan Desong,Sun Si,Guo Li
A novel thermal control coating was presented based on the thermochromism of manganite. The pigment of K-doped manganite nanoparticles was dispersed into polymer matrix to prepare the coating with curing below 200 \(^{\circ }\) C. The nanoparticles size mainly distributes around 100–200 nm, and it shows a comparable stoichiometric ratio. The phase transition of the nanoparticles was observed from ferromagnetic metallic to paramagnetic insulator state. With increasing K doping level, the phase transition temperature increases, achieving controllable adjustment. Coating surface with and without pore defect was obtained by different polymer matrix. A sharp emittance variation was observed with increasing temperature in K-doped coating. The variation magnitude of emittance is up to 0.46, which is attractive to space thermal control. It is suggested that the pigment content of 50 wt% is sufficient to realize a large emittance variation.
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高影响因子
CELLULOSE
·
2018
·Vol. 25
·期 5
·2987-2996
·
IF 3.809
Li Zhaoqian,Qiu Jia,Shi Yu,Pei Chonghua
Wettability-switchable bacterial cellulose/polyhemiaminal nanofiber aerogels were successfully prepared by a facile in situ polymerization of paraformaldehyde and 4,4′-diaminodiphenyl ether. The resultant aerogels displayed an interconnected porous structure, superior porosity, low density as well as hydrophobic–oleophilic properties. The aerogels could not only quickly and efficiently absorb the variety of oils or organic solvents from water, but also completely release the adsorbates in acid aqueous solutions by the aid of wettability switch (from hydrophobicity–oleophilicity to underwater superoleophobicity). Furthermore, the aerogels can continuously collect oils both on the water surface and in water-in-oil emulsions by a peristaltic pump.
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高影响因子
Journal of Earth Science
·
2019
·Vol. 30
·期 4
·861-869
·
IF 1.784
Zhang Caixiang,Liao Xiaoping,Lü You,Nan Chao
The ligand-stabilized soluble Mn(III) recognized as active intermediate can potentially mediate the attenuation of contaminants. In this study, the abiotic degradation behaviors of methyl parathion in the ligand stabilized Mn(III)-sulfite system were investigated. The results showed that the yield of soluble Mn(III) produced from the redox reaction of MnO 2 and oxalic acid was dependent linearly on the dosage of MnO 2 and caused the decomposition of methyl parathion up to 50.1% in Mn(III)-sulfite system after 30 minutes. The fitted pseudo-first-order reaction constants of methyl parathion degradation increased with the increasing of the amount of produced Mn(III) but was not effected linearly by the addition of sulfite. Other ligands, including pyrophosphate and oxalic acid, acted as effective complexing agents to stabilize soluble Mn(III), and exhibited competitive effect on methyl parathion degradation with sulfite. The formation of Mn(III)-sulfite complexes is the critical step in the system to produce abundant reactive oxygen species identified as SO 3 • - to facilitate methyl parathion degradation. The hydrolysis and oxidation of methyl parathion were acknowledged as two primary transformation mechanisms in Mn(III)-sulfite system. These findings indicate that naturally ligands-stabilized soluble Mn(III) can be generated and could oxidatively decompose organophosphate pesticides such as methyl parathion.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 6
·6209-6215
·
IF 2.914
Shi Hui,Bai Cuihua,Luo Donglin,Wang Wei,Zhou Changmin,Meharg Andrew A.,Yao Lixian
The environmental and human health risk posed by veterinary antibiotics is of global concern. Antibiotic uptake by herbal plants has been studied, but little is known about perennial woody fruit crops. Litchi ( Litchi chinensis Sonn.), a longevial fruit tree, is routinely fertilized with animal manure and, therefore, may be at risk of antibiotic uptake into its fruits. This study investigated the degradation of chlortetracycline and doxycycline present in manure used to amend orchard soil, and their subsequent assimilation by litchi plant, as affected by manure application rate. The results show that half-lives of chlortetracycline and doxycycline in soil were decreased by increased manure rate, with an average of 27 and 59 days, respectively. Chlortetracycline was readily transported to litchi shoots and increased with the growth of litchi plants. Doxycycline predominantly remained in the roots, and underwent growth dilution in the plants. The two tetracyclines could not be detected in fruits from litchi trees when applied with manures, at various rates, over 2 years. For litchi, chlortetracycline may pose human health risk through manure application, but doxycycline is unlikely to do so. Long-term field experiments are required to monitor antibiotic accumulation in fruits of perennial fruit trees fertilized with animal manure.
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BIOMEDICAL MICRODEVICES
·
2019
·Vol. 21
·期 1
·1-13
·
IF 2.327
Shen Yiren,Du Kun,Zou Lili,Zhou Xiaoming,Lv Rong,Gao Dayong,Qiu Bensheng,Ding Weiping
Freeze-drying is a promising approach for the long-term storage of erythrocytes at room temperature. Studies have shown that trehalose loaded into erythrocytes plays an important role in protecting erythrocytes against freeze-drying damage. Due to the impermeability of the erythrocyte membrane to trehalose, many methods have been developed to load trehalose into erythrocytes. However, these methods usually require multistep manual manipulation and long processing time; the adopted protocols are also diverse and not standardized. Thus, we develop an osmotically-based trehalose-loading microdevice (TLM) to rapidly, continuously, and automatically produce erythrocytes with loaded trehalose. In the TLM, trehalose is loaded through the erythrocyte membrane pores induced by hypotonic shock; then, the trehalose-loaded erythrocytes are rinsed to remove hemoglobin molecules and cell fragments, and the extracellular solution is restored to the isotonic state by integrating a rinsing-recovering design. First, the mixing function and the rinsing-recovering function were confirmed using a fluorescent solution. Then, the performance of the TLM was evaluated under various operating conditions with respect to the loading efficiency of trehalose, the hemolysis rate of erythrocytes ( ϕ ), the recovery rate of hemoglobin in erythrocytes ( φ ), and the separation efficiency of the TLM. Finally, the preliminary study of the freeze-drying of erythrocytes with loaded trehalose was accomplished using the TLM. The results showed that under the designated operating conditions, the loading efficiency for human erythrocytes reached ~21 mM in ~2 min with a ϕ value of ~17% and a φ value of ~74%. This study provides insights into the design of the on-chip loading of trehalose into erythrocytes and promotes the automation of life science studies on biochips.
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